登録情報 データベース : PDB / ID : 2a90 構造の表示 ダウンロードとリンクタイトル Crystal Structure of the tandem WWE domain of Drosophila Deltex 要素Deltex protein 詳細 キーワード METAL BINDING PROTEIN / WWE domain機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
Activated NOTCH1 Transmits Signal to the Nucleus / wing disc development / Notch receptor processing / Notch binding / positive regulation of Notch signaling pathway / negative regulation of Notch signaling pathway / Notch signaling pathway / RING-type E3 ubiquitin transferase / SH3 domain binding / endocytosis ... Activated NOTCH1 Transmits Signal to the Nucleus / wing disc development / Notch receptor processing / Notch binding / positive regulation of Notch signaling pathway / negative regulation of Notch signaling pathway / Notch signaling pathway / RING-type E3 ubiquitin transferase / SH3 domain binding / endocytosis / ubiquitin protein ligase activity / protein ubiquitination / zinc ion binding / nucleoplasm / cytosol / cytoplasm 類似検索 - 分子機能 Signal recognition particle alu RNA binding heterodimer, srp9/1 - #50 / Deltex, C-terminal / Deltex family / Deltex, C-terminal domain superfamily / Deltex C-terminal domain / WWE domain, subgroup / Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis. / Signal recognition particle alu RNA binding heterodimer, srp9/1 / WWE domain / WWE domain superfamily ... Signal recognition particle alu RNA binding heterodimer, srp9/1 - #50 / Deltex, C-terminal / Deltex family / Deltex, C-terminal domain superfamily / Deltex C-terminal domain / WWE domain, subgroup / Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis. / Signal recognition particle alu RNA binding heterodimer, srp9/1 / WWE domain / WWE domain superfamily / WWE domain / WWE domain profile. / Ring finger / Zinc finger RING-type profile. / Zinc finger, RING-type / Zinc finger, RING/FYVE/PHD-type / 2-Layer Sandwich / Alpha Beta 類似検索 - ドメイン・相同性生物種 Drosophila melanogaster (キイロショウジョウバエ)手法 X線回折 / シンクロトロン / 多波長異常分散 / 解像度 : 2.15 Å 詳細データ登録者 Zweifel, M.E. / Leahy, D.J. / Barrick, D. 引用ジャーナル : Structure / 年 : 2005タイトル : Structure and Notch Receptor Binding of the Tandem WWE Domain of Deltex.著者 : Zweifel, M.E. / Leahy, D.J. / Barrick, D. 履歴 登録 2005年7月10日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2005年11月22日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月30日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance
すべて表示 表示を減らす Remark 999 SEQUENCE The cysteines at residue positions 47, 155, 171 and 184 were converted to serines by site- ... SEQUENCE The cysteines at residue positions 47, 155, 171 and 184 were converted to serines by site-directed mutagenesis in the construct. These substitutions do not correspond to known mutations in the Deltex protein, but were made to improve the solubility and long-term stability of the polypeptide.