登録情報 データベース : PDB / ID : 2a36 構造の表示 ダウンロードとリンクタイトル Solution structure of the N-terminal SH3 domain of DRK 要素Protein E(sev)2B 詳細 キーワード SIGNALING PROTEIN / DROSOPHILA MELANOGASTER / SH3 FRAGMENT / DRK機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
sevenless binding / PI3K Cascade / Downstream signal transduction / Generation of second messenger molecules / PI-3K cascade:FGFR1 / PI-3K cascade:FGFR2 / PI-3K cascade:FGFR3 / PI-3K cascade:FGFR4 / RET signaling / Erythropoietin activates RAS ... sevenless binding / PI3K Cascade / Downstream signal transduction / Generation of second messenger molecules / PI-3K cascade:FGFR1 / PI-3K cascade:FGFR2 / PI-3K cascade:FGFR3 / PI-3K cascade:FGFR4 / RET signaling / Erythropoietin activates RAS / FLT3 Signaling / Signaling by CSF3 (G-CSF) / SOS-mediated signalling / Signaling by SCF-KIT / Regulation of KIT signaling / Signalling to RAS / DAP12 signaling / SHC-related events triggered by IGF1R / Role of LAT2/NTAL/LAB on calcium mobilization / FCERI mediated Ca+2 mobilization / SHC-mediated cascade:FGFR1 / FRS-mediated FGFR1 signaling / SHC-mediated cascade:FGFR2 / FRS-mediated FGFR2 signaling / SHC-mediated cascade:FGFR3 / FRS-mediated FGFR3 signaling / FRS-mediated FGFR4 signaling / SHC-mediated cascade:FGFR4 / Signal attenuation / Insulin receptor signalling cascade / FCERI mediated MAPK activation / PIP3 activates AKT signaling / GAB1 signalosome / PI3K events in ERBB2 signaling / NCAM signaling for neurite out-growth / PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling / Antigen activates B Cell Receptor (BCR) leading to generation of second messengers / SHC1 events in ERBB4 signaling / GRB2 events in EGFR signaling / SHC1 events in EGFR signaling / GRB2 events in ERBB2 signaling / EGFR Transactivation by Gastrin / torso signaling pathway / RAF/MAP kinase cascade / tracheal outgrowth, open tracheal system / R7 cell fate commitment / Spry regulation of FGF signaling / Negative regulation of FGFR1 signaling / Negative regulation of FGFR2 signaling / Negative regulation of FGFR3 signaling / Negative regulation of FGFR4 signaling / Regulation of signaling by CBL / sevenless signaling pathway / RHOU GTPase cycle / EGFR downregulation / Cargo recognition for clathrin-mediated endocytosis / RHO GTPases Activate WASPs and WAVEs / Regulation of actin dynamics for phagocytic cup formation / epithelial cell migration, open tracheal system / follicle cell of egg chamber development / Clathrin-mediated endocytosis / imaginal disc-derived wing morphogenesis / olfactory learning / short-term memory / COP9 signalosome / epidermal growth factor receptor binding / associative learning / regulation of MAPK cascade / positive regulation of cell size / fibroblast growth factor receptor signaling pathway / vascular endothelial growth factor receptor signaling pathway / positive regulation of TORC1 signaling / phosphotyrosine residue binding / sensory perception of sound / epidermal growth factor receptor signaling pathway / positive regulation of receptor-mediated endocytosis / signaling receptor complex adaptor activity / presynapse / insulin receptor signaling pathway / Ras protein signal transduction / positive regulation of ERK1 and ERK2 cascade / signal transduction / protein-containing complex / nucleoplasm / plasma membrane / cytoplasm 類似検索 - 分子機能 Grb2-like / SH3 Domains / SH3 domain / SH2 domain / Src homology 2 (SH2) domain profile. / Src homology 2 domains / SH3 type barrels. / SH2 domain / Src homology 3 domains / SH2 domain superfamily ... Grb2-like / SH3 Domains / SH3 domain / SH2 domain / Src homology 2 (SH2) domain profile. / Src homology 2 domains / SH3 type barrels. / SH2 domain / Src homology 3 domains / SH2 domain superfamily / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Roll / Mainly Beta 類似検索 - ドメイン・相同性生物種 Drosophila melanogaster (キイロショウジョウバエ)手法 溶液NMR / simulated annealing 詳細データ登録者 Forman-Kay, J.D. / Bezsonova, I. / Singer, A. / Choy, W.-Y. / Tollinger, M. 引用ジャーナル : Biochemistry / 年 : 2005タイトル : Structural Comparison of the Unstable drkN SH3 Domain and a Stable Mutant著者 : Bezsonova, I. / Singer, A. / Choy, W.-Y. / Tollinger, M. / Forman-Kay, J.D. 履歴 登録 2005年6月23日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2005年12月13日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月30日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2022年3月9日 Group : Database references / Derived calculationsカテゴリ : database_2 / pdbx_struct_assembly / pdbx_struct_oper_listItem : _database_2.pdbx_DOI / _database_2.pdbx_database_accession改定 1.4 2024年5月22日 Group : Data collection / カテゴリ : chem_comp_atom / chem_comp_bond
すべて表示 表示を減らす Remark 400 COMPOUND RESIDUE ANI PRESENT IN THE CONSTRAINT FILE DEFINES THE ALIGNMENT FRAME. INCLUDE THESE ... COMPOUND RESIDUE ANI PRESENT IN THE CONSTRAINT FILE DEFINES THE ALIGNMENT FRAME. INCLUDE THESE COORDINATES TO USE THE RESIDUAL DIPOLAR COUPLING AND/OR CARBONYL CHEMICAL SHIFT RESTRAINTS