登録情報 | データベース: PDB / ID: 1z3u |
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タイトル | Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in Tie2 Recognition |
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要素 | Angiopoietin-2 |
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キーワード | SIGNALING PROTEIN / Tie2 binding / angiogenesis / extracellular ligand |
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機能・相同性 | 機能・相同性情報
negative regulation of positive chemotaxis / Tie signaling pathway / glomerulus vasculature development / negative regulation of cell-substrate adhesion / germ cell development / negative regulation of blood vessel endothelial cell migration / maternal process involved in female pregnancy / animal organ regeneration / response to glucose / response to mechanical stimulus ...negative regulation of positive chemotaxis / Tie signaling pathway / glomerulus vasculature development / negative regulation of cell-substrate adhesion / germ cell development / negative regulation of blood vessel endothelial cell migration / maternal process involved in female pregnancy / animal organ regeneration / response to glucose / response to mechanical stimulus / Tie2 Signaling / negative regulation of angiogenesis / response to activity / cell projection / response to organic cyclic compound / receptor tyrosine kinase binding / cellular response to growth factor stimulus / positive regulation of angiogenesis / gene expression / angiogenesis / collagen-containing extracellular matrix / response to hypoxia / signaling receptor binding / signal transduction / extracellular space / extracellular region / metal ion binding類似検索 - 分子機能 Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 / Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 / Gamma Fibrinogen; Chain A, domain 1 / Gamma Fibrinogen, chain A, domain 1 / Fibrinogen, conserved site / Fibrinogen C-terminal domain signature. / Fibrinogen-related domains (FReDs) / Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 / Fibrinogen beta and gamma chains, C-terminal globular domain / Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain ...Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 / Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 / Gamma Fibrinogen; Chain A, domain 1 / Gamma Fibrinogen, chain A, domain 1 / Fibrinogen, conserved site / Fibrinogen C-terminal domain signature. / Fibrinogen-related domains (FReDs) / Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 / Fibrinogen beta and gamma chains, C-terminal globular domain / Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain / Fibrinogen-like, C-terminal / Fibrinogen C-terminal domain profile. / Few Secondary Structures / Irregular / Alpha-Beta Complex / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.25 Å |
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データ登録者 | Barton, W.A. / Tzvetkova, D. / Nikolov, D.B. |
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引用 | ジャーナル: Structure / 年: 2005 タイトル: Structure of the angiopoietin-2 receptor binding domain and identification of surfaces involved in Tie2 recognition. 著者: Barton, W.A. / Tzvetkova, D. / Nikolov, D.B. |
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履歴 | 登録 | 2005年3月14日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2005年7月12日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月30日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2021年10月20日 | Group: Database references / Derived calculations カテゴリ: database_2 / pdbx_struct_conn_angle ...database_2 / pdbx_struct_conn_angle / struct_conn / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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