- PDB-1yyp: Crystal structure of cytomegalovirus UL44 bound to C-terminal pep... -
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基本情報
登録情報
データベース: PDB / ID: 1yyp
タイトル
Crystal structure of cytomegalovirus UL44 bound to C-terminal peptide from CMV UL54
要素
DNA polymerase
DNA polymerase processivity factor
キーワード
REPLICATION/TRANSFERASE / PROCESSIVITY FOLD (SAME FOLD AS HSV UL42 / PCNA / AND HOMOTRIMERIC SLIDING CLAMPS) / REPLICATION-TRANSFERASE COMPLEX
機能・相同性
機能・相同性情報
bidirectional double-stranded viral DNA replication / DNA polymerase processivity factor activity / virion component / symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity / DNA replication / DNA-directed DNA polymerase / DNA-directed DNA polymerase activity / virus-mediated perturbation of host defense response / nucleotide binding / host cell nucleus / DNA binding 類似検索 - 分子機能
Herpesvirus polymerase accessory protein / Herpesvirus polymerase accessory protein / Box / Proliferating Cell Nuclear Antigen / Proliferating Cell Nuclear Antigen - #10 / DNA polymerase family B signature. / DNA-directed DNA polymerase, family B, conserved site / : / DNA polymerase family B / DNA polymerase family B, exonuclease domain ...Herpesvirus polymerase accessory protein / Herpesvirus polymerase accessory protein / Box / Proliferating Cell Nuclear Antigen / Proliferating Cell Nuclear Antigen - #10 / DNA polymerase family B signature. / DNA-directed DNA polymerase, family B, conserved site / : / DNA polymerase family B / DNA polymerase family B, exonuclease domain / DNA-directed DNA polymerase, family B, exonuclease domain / DNA-directed DNA polymerase, family B, multifunctional domain / DNA polymerase type-B family / DNA-directed DNA polymerase, family B / Ribonuclease H superfamily / Ribonuclease H-like superfamily / DNA/RNA polymerase superfamily / Alpha Beta 類似検索 - ドメイン・相同性
DNA polymerase catalytic subunit / DNA polymerase processivity factor 類似検索 - 構成要素
#1: ジャーナル: Mol.Cell / 年: 2004 タイトル: The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer
#2: ジャーナル: J.Virol. / 年: 2004 タイトル: Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit
#3: ジャーナル: J.Virol. / 年: 2004 タイトル: Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44
#4: ジャーナル: J.Virol. / 年: 1992 タイトル: Physical and functional interaction of human cytomegalovirus DNA polymerase and its accessory protein (ICP36) expressed in insect cells
履歴
登録
2005年2月25日
登録サイト: RCSB / 処理サイト: RCSB
改定 1.0
2005年12月27日
Provider: repository / タイプ: Initial release
改定 1.1
2008年4月30日
Group: Version format compliance
改定 1.2
2011年7月13日
Group: Advisory / Refinement description / Version format compliance
SEQUENCE AUTHOR STATES THAT THE SER 205 IS INDEED CORRECT AND IT MAY REPRESENT A DIFFERENT ISOLATE ...SEQUENCE AUTHOR STATES THAT THE SER 205 IS INDEED CORRECT AND IT MAY REPRESENT A DIFFERENT ISOLATE CYTOMEGALOVIRUS, REFERRING TO ERTL PF, POWELL KL. "PHYSICAL AND FUNCTIONAL INTERACTION OF HUMAN CYTOMEGALOVIRUS DNA POLYMERASE AND ITS ACCESSORY PROTEIN (ICP36) EXPRESSED IN INSECT CELLS." J VIROL. 1992 JUL;66(7):4126-33.