Entry | Database: PDB / ID: 1yxa |
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Title | Serpina3n, a murine orthologue of human antichymotrypsin |
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Components | serine (or cysteine) proteinase inhibitor, clade A, member 3N |
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Keywords | HYDROLASE INHIBITOR / Serpin / antichymotrypsin / protease inhibitor / reactive centre loop / plasma |
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Function / homology | Function and homology information
negative regulation of endopeptidase activity / response to cytokine / acute-phase response / response to bacterium / serine-type endopeptidase inhibitor activity / response to peptide hormone / extracellular space / extracellular regionSimilarity search - Function Antithrombin; Chain I, domain 2 / Antithrombin, subunit I, domain 2 / Alpha-1-antitrypsin; domain 1 / Alpha-1-antitrypsin, domain 1 / Serpin, conserved site / Serpins signature. / Serpin superfamily, domain 2 / Serpin family / Serpin domain / Serpin superfamily ...Antithrombin; Chain I, domain 2 / Antithrombin, subunit I, domain 2 / Alpha-1-antitrypsin; domain 1 / Alpha-1-antitrypsin, domain 1 / Serpin, conserved site / Serpins signature. / Serpin superfamily, domain 2 / Serpin family / Serpin domain / Serpin superfamily / Serpin superfamily, domain 1 / Serpin (serine protease inhibitor) / SERine Proteinase INhibitors / Roll / 2-Layer Sandwich / Mainly Beta / Alpha BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_mammal.gif) Mus musculus (house mouse) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 2.1 Å |
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Authors | Horvath, A.J. / Irving, J.A. / Law, R.H. / Rossjohn, J. / Bottomley, S.P. / Quinsey, N.S. / Pike, R.N. / Coughlin, P.B. / Whisstock, J.C. |
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Citation | Journal: J.Biol.Chem. / Year: 2005 Title: The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins. Authors: Horvath, A.J. / Irving, J.A. / Rossjohn, J. / Law, R.H. / Bottomley, S.P. / Quinsey, N.S. / Pike, R.N. / Coughlin, P.B. / Whisstock, J.C. |
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History | Deposition | Feb 20, 2005 | Deposition site: RCSB / Processing site: PDBJ |
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Revision 1.0 | Sep 6, 2005 | Provider: repository / Type: Initial release |
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Revision 1.1 | Apr 30, 2008 | Group: Version format compliance |
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Revision 1.2 | Jul 13, 2011 | Group: Advisory / Version format compliance |
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Revision 1.3 | Oct 11, 2017 | Group: Refinement description / Category: software |
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Revision 1.4 | Oct 25, 2023 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ref_seq_dif.details |
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Revision 1.5 | Nov 15, 2023 | Group: Data collection / Database references / Structure summary Category: audit_author / citation ...audit_author / citation / citation_author / struct_biol Item: _audit_author.identifier_ORCID / _citation.country ..._audit_author.identifier_ORCID / _citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _citation_author.name |
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