- PDB-1ygo: Solution Structure of the pelle Death Domain -
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基本情報
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データベース: PDB / ID: 1ygo
タイトル
Solution Structure of the pelle Death Domain
要素
Probable serine/threonine-protein kinase pelle
キーワード
TRANSFERASE / anti-parallel 6 helix bundle
機能・相同性
機能・相同性情報
determination of dorsal/ventral asymmetry / hemocyte proliferation / DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' / DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' / Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' / Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' / PLL kinase binds to TUB in the TL receptor 'signalling complex' / positive regulation of antifungal peptide production / TAK1-dependent IKK and NF-kappa-B activation / activated TAK1 mediates p38 MAPK activation ...determination of dorsal/ventral asymmetry / hemocyte proliferation / DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' / DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' / Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' / Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' / PLL kinase binds to TUB in the TL receptor 'signalling complex' / positive regulation of antifungal peptide production / TAK1-dependent IKK and NF-kappa-B activation / activated TAK1 mediates p38 MAPK activation / IRAK1 recruits IKK complex / IRAK2 mediated activation of TAK1 complex / TRAF6-mediated induction of TAK1 complex within TLR4 complex / IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation / IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation / JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 / Interleukin-1 signaling / zygotic specification of dorsal/ventral axis / positive regulation of hippo signaling / larval somatic muscle development / antifungal innate immune response / Toll signaling pathway / positive regulation of ubiquitin-dependent protein catabolic process / dorsal/ventral pattern formation / cytokine-mediated signaling pathway / positive regulation of protein catabolic process / cellular response to lipopolysaccharide / protein autophosphorylation / non-specific serine/threonine protein kinase / intracellular signal transduction / protein domain specific binding / protein phosphorylation / innate immune response / protein serine kinase activity / protein serine/threonine kinase activity / apoptotic process / ATP binding / nucleus / plasma membrane / cytoplasm / cytosol 類似検索 - 分子機能
Pelle, death domain / Death Domain, Fas / Death Domain, Fas / Death domain profile. / DEATH domain, found in proteins involved in cell death (apoptosis). / Death domain / Death domain / Death-like domain superfamily / Protein tyrosine and serine/threonine kinase / Serine-threonine/tyrosine-protein kinase, catalytic domain ...Pelle, death domain / Death Domain, Fas / Death Domain, Fas / Death domain profile. / DEATH domain, found in proteins involved in cell death (apoptosis). / Death domain / Death domain / Death-like domain superfamily / Protein tyrosine and serine/threonine kinase / Serine-threonine/tyrosine-protein kinase, catalytic domain / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性