登録情報 | データベース: PDB / ID: 1veu |
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タイトル | Crystal structure of the p14/MP1 complex at 2.15 A resolution |
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要素 | - Late endosomal/lysosomal Mp1 interacting protein
- Mitogen-activated protein kinase kinase 1 interacting protein 1
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キーワード | SIGNALING PROTEIN/PROTEIN BINDING / profilin / scaffold / adaptor / SIGNALING PROTEIN-PROTEIN BINDING COMPLEX |
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機能・相同性 | 機能・相同性情報
Energy dependent regulation of mTOR by LKB1-AMPK / MTOR signalling / Regulation of PTEN gene transcription / Macroautophagy / Amino acids regulate mTORC1 / regulation of cell-substrate junction organization / TP53 Regulates Metabolic Genes / mTORC1-mediated signalling / FNIP-folliculin RagC/D GAP / Ragulator complex ...Energy dependent regulation of mTOR by LKB1-AMPK / MTOR signalling / Regulation of PTEN gene transcription / Macroautophagy / Amino acids regulate mTORC1 / regulation of cell-substrate junction organization / TP53 Regulates Metabolic Genes / mTORC1-mediated signalling / FNIP-folliculin RagC/D GAP / Ragulator complex / MAP2K and MAPK activation / protein localization to cell junction / TORC1 signaling / fibroblast migration / kinase activator activity / positive regulation of TOR signaling / positive regulation of TORC1 signaling / Neutrophil degranulation / guanyl-nucleotide exchange factor activity / regulation of cell growth / cellular response to amino acid stimulus / protein localization / late endosome / late endosome membrane / positive regulation of MAPK cascade / molecular adaptor activity / lysosomal membrane類似検索 - 分子機能 Ragulator complex protein LAMTOR3 / Mitogen-activated protein kinase kinase 1 interacting / Mitogen-activated protein kinase kinase 1 interacting / Ragulator complex protein LAMTOR2-like / Dynein light chain 2a, cytoplasmic / Roadblock/LAMTOR2 domain / Roadblock/LC7 domain / Roadblock/LC7 domain / Beta-Lactamase / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 Ragulator complex protein LAMTOR3 / Ragulator complex protein LAMTOR2類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
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手法 | X線回折 / 分子置換 / 解像度: 2.15 Å |
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データ登録者 | Kurzbauer, R. / Teis, D. / Maurer-Stroh, S. / Eisenhaber, F. / Hekman, M. / Bourenkov, G.P. / Bartunik, H.D. / Huber, L.A. / Clausen, T. |
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引用 | ジャーナル: Proc.Natl.Acad.Sci.USA / 年: 2004 タイトル: Crystal structure of the p14/MP1 scaffolding complex: How a twin couple attaches mitogen- activated protein kinase signaling to late endosomes 著者: Kurzbauer, R. / Teis, D. / De Araujo, M.E. / Maurer-Stroh, S. / Eisenhaber, F. / Bourenkov, G.P. / Bartunik, H.D. / Hekman, M. / Rapp, U.R. / Huber, L.A. / Clausen, T. |
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履歴 | 登録 | 2004年4月5日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2004年8月3日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月27日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2023年10月25日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_conn / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag / _struct_ref_seq_dif.details |
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改定 1.4 | 2023年11月15日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond / Item: _chem_comp_atom.atom_id / _chem_comp_bond.atom_id_2 |
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