positive regulation of cellular component organization / : / Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / Resolution of Sister Chromatid Cohesion / COPI-independent Golgi-to-ER retrograde traffic / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / RHO GTPases Activate Formins / platelet-activating factor acetyltransferase activity / Loss of Nlp from mitotic centrosomes ...positive regulation of cellular component organization / : / Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / Resolution of Sister Chromatid Cohesion / COPI-independent Golgi-to-ER retrograde traffic / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / RHO GTPases Activate Formins / platelet-activating factor acetyltransferase activity / Loss of Nlp from mitotic centrosomes / Recruitment of mitotic centrosome proteins and complexes / Loss of proteins required for interphase microtubule organization from the centrosome / Recruitment of NuMA to mitotic centrosomes / Anchoring of the basal body to the plasma membrane / AURKA Activation by TPX2 / corpus callosum morphogenesis / establishment of planar polarity of embryonic epithelium / microtubule cytoskeleton organization involved in establishment of planar polarity / Regulation of PLK1 Activity at G2/M Transition / ameboidal-type cell migration / Separation of Sister Chromatids / interneuron migration / 1-alkyl-2-acetylglycerophosphocholine esterase complex / maintenance of centrosome location / microtubule sliding / COPI-independent Golgi-to-ER retrograde traffic / radial glia-guided pyramidal neuron migration / Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / cerebral cortex neuron differentiation / microtubule organizing center organization / central region of growth cone / acrosome assembly / positive regulation of embryonic development / reelin-mediated signaling pathway / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / Resolution of Sister Chromatid Cohesion / establishment of centrosome localization / positive regulation of cytokine-mediated signaling pathway / cortical microtubule organization / astral microtubule / nuclear membrane disassembly / RHO GTPases Activate Formins / layer formation in cerebral cortex / Separation of Sister Chromatids / auditory receptor cell development / Loss of Nlp from mitotic centrosomes / Recruitment of mitotic centrosome proteins and complexes / Loss of proteins required for interphase microtubule organization from the centrosome / Recruitment of NuMA to mitotic centrosomes / Anchoring of the basal body to the plasma membrane / AURKA Activation by TPX2 / vesicle transport along microtubule / positive regulation of dendritic spine morphogenesis / Regulation of PLK1 Activity at G2/M Transition / stem cell division / stereocilium / myeloid leukocyte migration / negative regulation of JNK cascade / microtubule plus-end binding / brain morphogenesis / motile cilium / retrograde axonal transport / nuclear migration / microtubule associated complex / osteoclast development / regulation of postsynapse organization / kinesin complex / dynein intermediate chain binding / dynein complex binding / cochlea development / regulation of GTPase activity / cell leading edge / transmission of nerve impulse / germ cell development / cytoplasmic microtubule / establishment of mitotic spindle orientation / microtubule-based process / neuromuscular process controlling balance / protein secretion / neuroblast proliferation / positive regulation of axon extension / lipid catabolic process / regulation of microtubule cytoskeleton organization / JNK cascade / axon cytoplasm / positive regulation of mitotic cell cycle / adult locomotory behavior / establishment of localization in cell / hippocampus development / phosphoprotein binding / neuron migration / Schaffer collateral - CA1 synapse / modulation of chemical synaptic transmission / brain development / cerebral cortex development / kinetochore / microtubule cytoskeleton organization / microtubule cytoskeleton / cell migration Similarity search - Function
Mass: 18.015 Da / Num. of mol.: 181 / Source method: isolated from a natural source / Formula: H2O
Sequence details
INITIAL 2 RESIDUES ARE CLONING ARTIFACTS.
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Experimental details
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Experiment
Experiment
Method: X-RAY DIFFRACTION / Number of used crystals: 1
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Sample preparation
Crystal
Density Matthews: 2.1 Å3/Da / Density % sol: 49.6 %
Crystal grow
Method: microbatch / pH: 4.5 Details: CRYSTALS WERE GROWN USING SITTING-DROP VAPOUR-DIFFUSION UNDER MINERAL OIL USING A 1:1 MIXTURE OF PROTEIN AND 1.7 M (NH4)2SO4 AND 0.1 M NA3-CITRATE, PH 4.5