登録情報 | データベース: PDB / ID: 1sr9 |
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タイトル | Crystal Structure of LeuA from Mycobacterium tuberculosis |
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要素 | 2-isopropylmalate synthase |
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キーワード | TRANSFERASE / TIM barrel |
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機能・相同性 | 機能・相同性情報
2-isopropylmalate synthase / 2-isopropylmalate synthase activity / acetyl-CoA C-acetyltransferase activity / L-leucine biosynthetic process / potassium ion binding / amino acid biosynthetic process / manganese ion binding / magnesium ion binding / zinc ion binding / extracellular region ...2-isopropylmalate synthase / 2-isopropylmalate synthase activity / acetyl-CoA C-acetyltransferase activity / L-leucine biosynthetic process / potassium ion binding / amino acid biosynthetic process / manganese ion binding / magnesium ion binding / zinc ion binding / extracellular region / plasma membrane / cytoplasm類似検索 - 分子機能 Arc Repressor Mutant - #20 / Alpha-isopropylmalate synthase LeuA, regulatory domain / Helix Hairpins - #1400 / 2-isopropylmalate synthase / LeuA, N-terminal catalytic TIM barrel domain / 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain / 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily / LeuA allosteric (dimerisation) domain / LeuA allosteric (dimerisation) domain / Alpha-isopropylmalate and homocitrate synthases signature 2. ...Arc Repressor Mutant - #20 / Alpha-isopropylmalate synthase LeuA, regulatory domain / Helix Hairpins - #1400 / 2-isopropylmalate synthase / LeuA, N-terminal catalytic TIM barrel domain / 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain / 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily / LeuA allosteric (dimerisation) domain / LeuA allosteric (dimerisation) domain / Alpha-isopropylmalate and homocitrate synthases signature 2. / Alpha-isopropylmalate and homocitrate synthases signature 1. / Alpha-isopropylmalate/homocitrate synthase, conserved site / Arc Repressor Mutant / Pyruvate carboxyltransferase / HMGL-like / Pyruvate carboxyltransferase domain. / Double Stranded RNA Binding Domain / Aldolase class I / Helix Hairpins / Aldolase-type TIM barrel / TIM Barrel / Alpha-Beta Barrel / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 3-METHYL-2-OXOBUTANOIC ACID / 2-isopropylmalate synthase / 2-isopropylmalate synthase類似検索 - 構成要素 |
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生物種 | ![](img/tx_bacteria.gif) Mycobacterium tuberculosis (結核菌) |
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手法 | X線回折 / 多波長異常分散 / 解像度: 2 Å |
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データ登録者 | Koon, N. / Squire, C.J. / Baker, E.N. |
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引用 | ジャーナル: Proc.Natl.Acad.Sci.USA / 年: 2004 タイトル: Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis 著者: Koon, N. / Squire, C.J. / Baker, E.N. |
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履歴 | 登録 | 2004年3月22日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2004年5月18日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月29日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2017年10月11日 | Group: Refinement description / カテゴリ: software |
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