The biological assembly is the macromolecular complex in the asymmetric unit and consists of two DNA binding domains (EcR and RXR), bound to an ecdysone response element (IR-1)
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Components
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DNA chain , 2 types, 2 molecules CD
#1: DNA chain
EcdsyoneResponseElement
Mass: 5501.567 Da / Num. of mol.: 1 / Source method: obtained synthetically
#2: DNA chain
EcdysoneResponseElement
Mass: 5492.553 Da / Num. of mol.: 1 / Source method: obtained synthetically
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Protein , 2 types, 2 molecules AB
#3: Protein
RetinoicacidreceptorRXR-alpha
Mass: 9375.969 Da / Num. of mol.: 1 / Fragment: Retinoid X Receptor DNA binding domain Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Gene: RXRA / Plasmid: pGEX-4T1 / Species (production host): Escherichia coli / Production host: Escherichia coli BL21(DE3) (bacteria) / Strain (production host): BL21DE3 / References: UniProt: P19793
#4: Protein
Ecdysonereceptor / Ecdysteroid receptor / 20-hydroxy-ecdysone receptor / 20E receptor
Mass: 12554.819 Da / Num. of mol.: 1 / Fragment: Ecdsyone Receptor DNA binding domain Source method: isolated from a genetically manipulated source Source: (gene. exp.) Drosophila melanogaster (fruit fly) / Gene: ECR / Plasmid: pGEX-2T / Species (production host): Escherichia coli / Production host: Escherichia coli BL21(DE3) (bacteria) / Strain (production host): BL21DE3 / References: UniProt: P34021
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