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Yorodumi- PDB-1pk2: SOLUTION STRUCTURE OF THE TISSUE-TYPE PLASMINOGEN ACTIVATOR KRING... -
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-Basic information
Entry | Database: PDB / ID: 1pk2 | |||||||||
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Title | SOLUTION STRUCTURE OF THE TISSUE-TYPE PLASMINOGEN ACTIVATOR KRINGLE 2 DOMAIN COMPLEXED TO 6-AMINOHEXANOIC ACID AN ANTIFIBRINOLYTIC DRUG | |||||||||
Components | TISSUE-TYPE PLASMINOGEN ACTIVATOR | |||||||||
Keywords | PLASMINOGEN ACTIVATOR | |||||||||
Function / homology | Function and homology information t-plasminogen activator / prevention of polyspermy / trans-synaptic signaling by BDNF, modulating synaptic transmission / Signaling by PDGF / negative regulation of plasminogen activation / Dissolution of Fibrin Clot / smooth muscle cell migration / plasminogen activation / platelet-derived growth factor receptor signaling pathway / negative regulation of fibrinolysis ...t-plasminogen activator / prevention of polyspermy / trans-synaptic signaling by BDNF, modulating synaptic transmission / Signaling by PDGF / negative regulation of plasminogen activation / Dissolution of Fibrin Clot / smooth muscle cell migration / plasminogen activation / platelet-derived growth factor receptor signaling pathway / negative regulation of fibrinolysis / serine protease inhibitor complex / fibrinolysis / secretory granule / negative regulation of proteolysis / phosphoprotein binding / Schaffer collateral - CA1 synapse / protein modification process / blood coagulation / apical part of cell / response to hypoxia / serine-type endopeptidase activity / signaling receptor binding / glutamatergic synapse / cell surface / proteolysis / extracellular space / extracellular exosome / extracellular region / cytoplasm Similarity search - Function | |||||||||
Biological species | Homo sapiens (human) | |||||||||
Method | SOLUTION NMR | |||||||||
Authors | Llinas, M. / Byeon, I.-J.L. | |||||||||
Citation | Journal: J.Mol.Biol. / Year: 1991 Title: Solution structure of the tissue-type plasminogen activator kringle 2 domain complexed to 6-aminohexanoic acid an antifibrinolytic drug. Authors: Byeon, I.J. / Llinas, M. #1: Journal: Eur.J.Biochem. / Year: 1991 Title: Kringle-2 Domain of the Tissue-Type Plasminogen Activator H-NMR Assignments and Secondary Structure Authors: Byeon, I.-J.L. / Kelley, R.F. / Llinas, M. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1pk2.cif.gz | 38.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1pk2.ent.gz | 25.8 KB | Display | PDB format |
PDBx/mmJSON format | 1pk2.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1pk2_validation.pdf.gz | 356.2 KB | Display | wwPDB validaton report |
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Full document | 1pk2_full_validation.pdf.gz | 362.2 KB | Display | |
Data in XML | 1pk2_validation.xml.gz | 4.7 KB | Display | |
Data in CIF | 1pk2_validation.cif.gz | 6.1 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/pk/1pk2 ftp://data.pdbj.org/pub/pdb/validation_reports/pk/1pk2 | HTTPS FTP |
-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 9869.960 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / References: UniProt: P00750, t-plasminogen activator |
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#2: Chemical | ChemComp-ACA / |
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Processing
NMR ensemble | Conformers submitted total number: 1 |
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