Entry Database : PDB / ID : 1p4q Structure visualization Downloads & linksTitle Solution structure of the CITED2 transactivation domain in complex with the p300 CH1 domain ComponentsCbp/p300-interacting transactivator 2 E1A-associated protein p300 DetailsKeywords TRANSCRIPTION/TRANSFERASE / helix / protein-protein complex / TRANSCRIPTION-TRANSFERASE COMPLEXFunction / homology Function and homology informationFunction Domain/homology Component
embryonic process involved in female pregnancy / cranial nerve morphogenesis / TFAP2 (AP-2) family regulates transcription of other transcription factors / left/right pattern formation / pulmonary artery morphogenesis / embryonic heart tube left/right pattern formation / regulation of animal organ formation / adrenal cortex formation / nodal signaling pathway / embryonic camera-type eye morphogenesis ... embryonic process involved in female pregnancy / cranial nerve morphogenesis / TFAP2 (AP-2) family regulates transcription of other transcription factors / left/right pattern formation / pulmonary artery morphogenesis / embryonic heart tube left/right pattern formation / regulation of animal organ formation / adrenal cortex formation / nodal signaling pathway / embryonic camera-type eye morphogenesis / sex determination / positive regulation of male gonad development / behavioral defense response / endocardial cushion development / protein propionyltransferase activity / peptidyl-lysine propionylation / histone lactyltransferase activity / peptidyl-lysine crotonylation / peptidyl-lysine butyrylation / histone butyryltransferase activity / histone H3K122 acetyltransferase activity / swimming / peptide butyryltransferase activity / histone H2B acetyltransferase activity / thigmotaxis / determination of left/right asymmetry in lateral mesoderm / positive regulation of peroxisome proliferator activated receptor signaling pathway / granulocyte differentiation / peptide 2-hydroxyisobutyryltransferase activity / histone crotonyltransferase activity / lens morphogenesis in camera-type eye / left/right axis specification / NOTCH2 intracellular domain regulates transcription / peptidyl-lysine acetylation / positive regulation of cell-cell adhesion / lysine N-acetyltransferase activity, acting on acetyl phosphate as donor / negative regulation of cardiac muscle cell proliferation / response to fluid shear stress / histone H4 acetyltransferase activity / trophectodermal cell differentiation / cellular response to L-leucine / internal peptidyl-lysine acetylation / histone H3 acetyltransferase activity / peripheral nervous system development / cardiac neural crest cell development involved in heart development / NFE2L2 regulating ER-stress associated genes / peptide N-acetyltransferase activity / acetylation-dependent protein binding / Activation of the TFAP2 (AP-2) family of transcription factors / NFE2L2 regulating inflammation associated genes / NGF-stimulated transcription / STAT3 nuclear events downstream of ALK signaling / Polo-like kinase mediated events / histone H3K18 acetyltransferase activity / LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production / N-terminal peptidyl-lysine acetylation / histone H3K27 acetyltransferase activity / NFE2L2 regulates pentose phosphate pathway genes / NFE2L2 regulating MDR associated enzymes / regulation of androgen receptor signaling pathway / positive regulation by host of viral transcription / regulation of mitochondrion organization / bone morphogenesis / determination of left/right symmetry / Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells / RUNX3 regulates NOTCH signaling / face morphogenesis / NOTCH4 Intracellular Domain Regulates Transcription / Regulation of FOXO transcriptional activity by acetylation / Regulation of gene expression by Hypoxia-inducible Factor / regulation of glycolytic process / Nuclear events mediated by NFE2L2 / Regulation of NFE2L2 gene expression / NOTCH3 Intracellular Domain Regulates Transcription / platelet formation / NFE2L2 regulating anti-oxidant/detoxification enzymes / TRAF6 mediated IRF7 activation / megakaryocyte development / nuclear androgen receptor binding / regulation of tubulin deacetylation / macrophage derived foam cell differentiation / FOXO-mediated transcription of cell death genes / NFE2L2 regulating tumorigenic genes / peptide-lysine-N-acetyltransferase activity / STAT family protein binding / histone acetyltransferase binding / internal protein amino acid acetylation / ventricular septum morphogenesis / acyltransferase activity / protein acetylation / fat cell differentiation / LBD domain binding / heart looping / Formation of paraxial mesoderm / RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known / outflow tract morphogenesis / positive regulation of transforming growth factor beta receptor signaling pathway / SMAD binding / skeletal muscle cell differentiation / PI5P Regulates TP53 Acetylation Similarity search - Function Helix Hairpins - #2200 / CITED / CITED / CREB-binding Protein; Chain A / TAZ domain / Nuclear receptor coactivator, CREB-bp-like, interlocking / Nuclear receptor coactivator, CREB-bp-like, interlocking domain superfamily / Creb binding / Zinc finger, TAZ-type / TAZ domain superfamily ... Helix Hairpins - #2200 / CITED / CITED / CREB-binding Protein; Chain A / TAZ domain / Nuclear receptor coactivator, CREB-bp-like, interlocking / Nuclear receptor coactivator, CREB-bp-like, interlocking domain superfamily / Creb binding / Zinc finger, TAZ-type / TAZ domain superfamily / TAZ zinc finger / Zinc finger TAZ-type profile. / TAZ zinc finger, present in p300 and CBP / Coactivator CBP, KIX domain / CREB-binding protein/p300, atypical RING domain / CBP/p300-type histone acetyltransferase domain / CBP/p300, atypical RING domain superfamily / KIX domain / CREB-binding protein/p300, atypical RING domain / KIX domain profile. / CBP/p300-type histone acetyltransferase (HAT) domain profile. / Histone acetyltransferase Rtt109/CBP / Coactivator CBP, KIX domain superfamily / Histone acetylation protein / Histone acetylation protein / Zinc finger ZZ-type signature. / Zinc-binding domain, present in Dystrophin, CREB-binding protein. / Zinc finger, ZZ type / Zinc finger, ZZ-type / Zinc finger, ZZ-type superfamily / Zinc finger ZZ-type profile. / Helix Hairpins / Nuclear receptor coactivator, interlocking / Helix non-globular / Special / Bromodomain, conserved site / Bromodomain signature. / Bromodomain / Bromodomain profile. / bromo domain / Bromodomain / Bromodomain-like superfamily / Zinc finger, RING/FYVE/PHD-type / Up-down Bundle / Mainly Alpha Similarity search - Domain/homologyBiological species Homo sapiens (human)Method SOLUTION NMR / simulated annealing DetailsAuthors Freedman, S.J. / Sun, Z.-Y.J. / Kung, A.L. / France, D.S. / Wagner, G. / Eck, M.J. Citation Show more 1 items Show lessHistory Deposition Apr 23, 2003 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Jul 1, 2003 Provider : repository / Type : Initial releaseRevision 1.1 Apr 29, 2008 Group : Version format complianceRevision 1.2 Jul 13, 2011 Group : Version format complianceRevision 1.3 Feb 1, 2017 Group : Structure summary
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