登録情報 データベース : PDB / ID : 1o86 構造の表示 ダウンロードとリンクタイトル Crystal Structure of Human Angiotensin Converting Enzyme in complex with lisinopril. 要素ANGIOTENSIN CONVERTING ENZYME 詳細 キーワード HYDROLASE/HYDROLASE INHIBITOR / METALLOPROTEASE / PEPTIDYL DIPEPTIDASE / TYPE-I MEMBRANE-ANCHORED PROTEIN / HYDROLASE-HYDROLASE INHIBITOR COMPLEX機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
mononuclear cell proliferation / cell proliferation in bone marrow / bradykinin receptor binding / regulation of angiotensin metabolic process / exopeptidase activity / substance P catabolic process / peptidyl-dipeptidase A / tripeptidyl-peptidase activity / regulation of renal output by angiotensin / negative regulation of calcium ion import ... mononuclear cell proliferation / cell proliferation in bone marrow / bradykinin receptor binding / regulation of angiotensin metabolic process / exopeptidase activity / substance P catabolic process / peptidyl-dipeptidase A / tripeptidyl-peptidase activity / regulation of renal output by angiotensin / negative regulation of calcium ion import / positive regulation of peptidyl-cysteine S-nitrosylation / response to laminar fluid shear stress / negative regulation of gap junction assembly / metallodipeptidase activity / positive regulation of systemic arterial blood pressure / cellular response to aldosterone / hormone catabolic process / bradykinin catabolic process / angiogenesis involved in coronary vascular morphogenesis / response to thyroid hormone / antigen processing and presentation of peptide antigen via MHC class I / negative regulation of glucose import / vasoconstriction / hormone metabolic process / neutrophil mediated immunity / regulation of smooth muscle cell migration / regulation of hematopoietic stem cell proliferation / mitogen-activated protein kinase binding / embryo development ending in birth or egg hatching / chloride ion binding / mitogen-activated protein kinase kinase binding / positive regulation of neurogenesis / arachidonic acid secretion / eating behavior / post-transcriptional regulation of gene expression / heterocyclic compound binding / lung alveolus development / heart contraction / peptide catabolic process / response to dexamethasone / regulation of heart rate by cardiac conduction / regulation of systemic arterial blood pressure by renin-angiotensin / regulation of vasoconstriction / hematopoietic stem cell differentiation / peptidyl-dipeptidase activity / blood vessel remodeling / amyloid-beta metabolic process / angiotensin maturation / animal organ regeneration / Metabolism of Angiotensinogen to Angiotensins / positive regulation of vasoconstriction / carboxypeptidase activity / sperm midpiece / blood vessel diameter maintenance / response to nutrient levels / basal plasma membrane / kidney development / angiotensin-activated signaling pathway / female pregnancy / cellular response to glucose stimulus / brush border membrane / regulation of synaptic plasticity / metalloendopeptidase activity / regulation of blood pressure / metallopeptidase activity / male gonad development / peptidase activity / actin binding / spermatogenesis / endopeptidase activity / response to lipopolysaccharide / lysosome / calmodulin binding / response to hypoxia / endosome / response to xenobiotic stimulus / positive regulation of apoptotic process / external side of plasma membrane / negative regulation of gene expression / proteolysis / extracellular space / zinc ion binding / extracellular exosome / extracellular region / plasma membrane 類似検索 - 分子機能 Peptidase family M2 domain profile. / Peptidase M2, peptidyl-dipeptidase A / Angiotensin-converting enzyme / Neutral zinc metallopeptidases, zinc-binding region signature. 類似検索 - ドメイン・相同性 Lisinopril / GLYCINE / Chem-LPR / Angiotensin-converting enzyme / Angiotensin-converting enzyme 類似検索 - 構成要素生物種 HOMO SAPIENS (ヒト)手法 X線回折 / シンクロトロン / 多波長異常分散 / 解像度 : 2 Å 詳細データ登録者 Natesh, R. / Schwager, S.L.U. / Sturrock, E.D. / Acharya, K.R. 引用ジャーナル : Nature / 年 : 2003タイトル : Crystal Structure of the Human Angiotensin-Converting Enzyme-Lisinopril Complex著者 : Natesh, R. / Schwager, S.L.U. / Sturrock, E.D. / Acharya, K.R. 履歴 登録 2002年11月25日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2003年2月7日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Atomic model / Database references ... Atomic model / Database references / Derived calculations / Non-polymer description / Structure summary / Version format compliance 改定 1.2 2013年3月6日 Group : Other
すべて表示 表示を減らす Remark 700 SHEET DETERMINATION METHOD: AUTHOR PROVIDED.