登録情報 データベース : PDB / ID : 1o7y 構造の表示 ダウンロードとリンクタイトル Crystal structure of IP-10 M-form 要素SMALL INDUCIBLE CYTOKINE B10 詳細 キーワード CHEMOKINE / INTERFERON INDUCTION / CHEMOTAXIS / INFLAMMATORY RESPONSE機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
regulation of T cell chemotaxis / negative regulation of myoblast fusion / CXCR3 chemokine receptor binding / regulation of endothelial tube morphogenesis / cellular response to interleukin-17 / CXCR chemokine receptor binding / response to auditory stimulus / cAMP-dependent protein kinase regulator activity / negative regulation of myoblast differentiation / T cell chemotaxis ... regulation of T cell chemotaxis / negative regulation of myoblast fusion / CXCR3 chemokine receptor binding / regulation of endothelial tube morphogenesis / cellular response to interleukin-17 / CXCR chemokine receptor binding / response to auditory stimulus / cAMP-dependent protein kinase regulator activity / negative regulation of myoblast differentiation / T cell chemotaxis / response to vitamin D / positive regulation of monocyte chemotaxis / chemokine-mediated signaling pathway / blood circulation / Chemokine receptors bind chemokines / endothelial cell activation / chemokine activity / muscle organ development / chemoattractant activity / Interleukin-10 signaling / positive regulation of T cell migration / antiviral innate immune response / neutrophil chemotaxis / negative regulation of angiogenesis / positive regulation of release of sequestered calcium ion into cytosol / response to gamma radiation / adenylate cyclase-activating G protein-coupled receptor signaling pathway / cellular response to virus / chemotaxis / antimicrobial humoral immune response mediated by antimicrobial peptide / cell-cell signaling / heparin binding / regulation of cell population proliferation / cellular response to heat / G alpha (i) signalling events / cellular response to lipopolysaccharide / regulation of apoptotic process / cell surface receptor signaling pathway / inflammatory response / G protein-coupled receptor signaling pathway / external side of plasma membrane / signaling receptor binding / positive regulation of cell population proliferation / signal transduction / positive regulation of transcription by RNA polymerase II / extracellular space / extracellular region 類似検索 - 分子機能 CXC chemokine / CXC chemokine, conserved site / Small cytokines (intercrine/chemokine) C-x-C subfamily signature. / CXC Chemokine domain / Chemokine beta/gamma/delta / Intercrine alpha family (small cytokine C-X-C) (chemokine CXC). / Chemokine interleukin-8-like domain / Chemokine interleukin-8-like superfamily / Small cytokines (intecrine/chemokine), interleukin-8 like / OB fold (Dihydrolipoamide Acetyltransferase, E2P) - #40 ... CXC chemokine / CXC chemokine, conserved site / Small cytokines (intercrine/chemokine) C-x-C subfamily signature. / CXC Chemokine domain / Chemokine beta/gamma/delta / Intercrine alpha family (small cytokine C-X-C) (chemokine CXC). / Chemokine interleukin-8-like domain / Chemokine interleukin-8-like superfamily / Small cytokines (intecrine/chemokine), interleukin-8 like / OB fold (Dihydrolipoamide Acetyltransferase, E2P) - #40 / OB fold (Dihydrolipoamide Acetyltransferase, E2P) / Beta Barrel / Mainly Beta 類似検索 - ドメイン・相同性生物種 HOMO SAPIENS (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 3 Å 詳細データ登録者 Swaminathan, G.J. / Holloway, D.E. / Papageorgiou, A.C. / Acharya, K.R. 引用ジャーナル : Structure / 年 : 2003タイトル : Crystal Structures of Oligomeric Forms of the Ip-10/Cxcl10 Chemokine著者 : Swaminathan, G.J. / Holloway, D.E. / Colvin, R.A. / Campanella, G.K. / Papageorgiou, A.C. / Luster, A.D. / Acharya, K.R. 履歴 登録 2002年11月20日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2003年5月8日 Provider : repository / タイプ : Initial release改定 1.1 2011年5月8日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2019年7月24日 Group : Data collection / カテゴリ : diffrn_source / Item : _diffrn_source.pdbx_synchrotron_site改定 1.4 2023年12月13日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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