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Yorodumi- PDB-1ntn: THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1ntn | ||||||
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Title | THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION | ||||||
Components | NEUROTOXIN I | ||||||
Keywords | POSTSYNAPTIC NEUROTOXIN | ||||||
Function / homology | Function and homology information acetylcholine receptor inhibitor activity / ion channel regulator activity / toxin activity / extracellular region Similarity search - Function | ||||||
Biological species | Naja oxiana (Central Asian cobra) | ||||||
Method | X-RAY DIFFRACTION / Resolution: 1.9 Å | ||||||
Authors | Mikhailov, A.M. / Nickitenko, A.V. / Vainshtein, B.K. / Betzel, C. / Wilson, K. | ||||||
Citation | Journal: Febs Lett. / Year: 1993 Title: Three-dimensional structure of neurotoxin-1 from Naja naja oxiana venom at 1.9 A resolution. Authors: Nickitenko, A.V. / Michailov, A.M. / Betzel, C. / Wilson, K.S. #1: Journal: FEBS Lett. / Year: 1993 Title: Three-Dimensional Structure of Neurotoxin-1 from Naja Naja Oxiana Venom at 1.9 Angstroms Resolution Authors: Nickitenko, A.V. / Mikhailov, A.M. / Betzel, C. / Wilson, K.S. #2: Journal: Bioorg.Khim. / Year: 1991 Title: Spatial Organization of Backbone of the Neurotoxin-I Molecule from the Naja Naja Oxiana Venom and its Crystal Packing (in Russian) Authors: Mikhailov, A.M. / Nickitenko, A.V. / Chetverina, E.V. / Trakhanov, S.D. / Vainshtein, B.K. #3: Journal: FEBS Lett. / Year: 1990 Title: Crystallization and Preliminary X-Ray Diffraction Study of Neurotoxin-I from Naja Naja Oxiana Venom Authors: Mikhailov, A.M. / Nickitenko, A.V. / Trakhanov, S.D. / Vainshtein, B.K. / Chetverina, E.V. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1ntn.cif.gz | 22.5 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1ntn.ent.gz | 16.7 KB | Display | PDB format |
PDBx/mmJSON format | 1ntn.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1ntn_validation.pdf.gz | 412.4 KB | Display | wwPDB validaton report |
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Full document | 1ntn_full_validation.pdf.gz | 418.1 KB | Display | |
Data in XML | 1ntn_validation.xml.gz | 6.8 KB | Display | |
Data in CIF | 1ntn_validation.cif.gz | 8.4 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/nt/1ntn ftp://data.pdbj.org/pub/pdb/validation_reports/nt/1ntn | HTTPS FTP |
-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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Unit cell |
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Atom site foot note | 1: CIS PROLINE - PRO 7 2: RESIDUES 69 - 71 ARE POORLY DEFINED IN THE ELECTRON-DENSITY MAP AND IN REFINEMENT AND MAY BE CORRECTED AT HIGHER RESOLUTION. |
-Components
#1: Protein | Mass: 7942.115 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Naja oxiana (Central Asian cobra) / References: UniProt: P01382 |
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#2: Water | ChemComp-HOH / |
-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION |
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-Sample preparation
Crystal | Density Matthews: 2.15 Å3/Da / Density % sol: 42.68 % | ||||||||||||||||||||||||||||||||||||
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Crystal grow | *PLUS pH: 4.7 / Method: unknown | ||||||||||||||||||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Radiation | Scattering type: x-ray |
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Radiation wavelength | Relative weight: 1 |
Reflection | *PLUS Highest resolution: 1.9 Å / Lowest resolution: 38 Å / Rmerge(I) obs: 0.044 |
-Processing
Software | Name: PROLSQ / Classification: refinement | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Refinement | Resolution: 1.9→38 Å / σ(F): 1 Details: RESIDUES 69 - 71 ARE POORLY DEFINED IN THE ELECTRON-DENSITY MAP AND IN REFINEMENT
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Refinement step | Cycle: LAST / Resolution: 1.9→38 Å
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Refine LS restraints |
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Refinement | *PLUS Lowest resolution: 6 Å / Num. reflection obs: 4766 / Rfactor obs: 0.193 / Rfactor Rwork: 0.193 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Solvent computation | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints | *PLUS
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