+
Open data
-
Basic information
Entry | Database: PDB / ID: 1nct | ||||||
---|---|---|---|---|---|---|---|
Title | TITIN MODULE M5, N-TERMINALLY EXTENDED, NMR | ||||||
![]() | TITIN | ||||||
![]() | MUSCLE PROTEIN / CELL ADHESION / GLYCOPROTEIN / TRANSMEMBRANE / BRAIN / IMMUNOGLOBULIN FOLD / ALTERNATIVE SPLICING | ||||||
Function / homology | ![]() sarcomerogenesis / structural molecule activity conferring elasticity / telethonin binding / skeletal muscle myosin thick filament assembly / cardiac myofibril assembly / muscle alpha-actinin binding / detection of muscle stretch / cardiac muscle tissue morphogenesis / regulation of catalytic activity / cardiac muscle hypertrophy ...sarcomerogenesis / structural molecule activity conferring elasticity / telethonin binding / skeletal muscle myosin thick filament assembly / cardiac myofibril assembly / muscle alpha-actinin binding / detection of muscle stretch / cardiac muscle tissue morphogenesis / regulation of catalytic activity / cardiac muscle hypertrophy / mitotic chromosome condensation / Striated Muscle Contraction / actinin binding / M band / I band / cardiac muscle cell development / regulation of protein kinase activity / structural constituent of muscle / sarcomere organization / skeletal muscle thin filament assembly / striated muscle thin filament / striated muscle contraction / cardiac muscle contraction / protein kinase A signaling / condensed nuclear chromosome / muscle contraction / positive regulation of protein secretion / Z disc / response to calcium ion / : / actin filament binding / Platelet degranulation / protein tyrosine kinase activity / protease binding / non-specific serine/threonine protein kinase / calmodulin binding / phosphorylation / protein serine kinase activity / protein serine/threonine kinase activity / calcium ion binding / positive regulation of gene expression / protein kinase binding / enzyme binding / extracellular exosome / extracellular region / ATP binding / identical protein binding / cytosol Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | SOLUTION NMR | ||||||
![]() | Pfuhl, M. / Pastore, A. | ||||||
![]() | ![]() Title: When a module is also a domain: the role of the N terminus in the stability and the dynamics of immunoglobulin domains from titin. Authors: Pfuhl, M. / Improta, S. / Politous, A.S. / Pastore, A. #1: ![]() Title: Immunoglobulin-Like Modules from Titin I-Band Extensible Components of Muscle Elasticity Authors: Improta, S. / Politou, A.S. / Pastore, A. #2: ![]() Title: Tertiary Structure of an Immunoglobulin-Like Domain from the Giant Muscle Protein Titin: A New Member of the I Set Authors: Pfuhl, M. / Pastore, A. #3: ![]() Title: Secondary Structure Determination by NMR Spectroscopy of an Immunoglobulin-Like Domain from the Giant Muscle Protein Titin Authors: Pfuhl, M. / Gautel, M. / Politou, A.S. / Joseph, C. / Pastore, A. #4: ![]() Title: Immunoglobulin-Type Domains of Titin are Stabilized by Amino-Terminal Extension Authors: Politou, A.S. / Gautel, M. / Joseph, C. / Pastore, A. | ||||||
History |
|
-
Structure visualization
Structure viewer | Molecule: ![]() ![]() |
---|
-
Downloads & links
-
Download
PDBx/mmCIF format | ![]() | 56.4 KB | Display | ![]() |
---|---|---|---|---|
PDB format | ![]() | 28.3 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 331.9 KB | Display | ![]() |
---|---|---|---|---|
Full document | ![]() | 340.8 KB | Display | |
Data in XML | ![]() | 4.6 KB | Display | |
Data in CIF | ![]() | 5.8 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
-
Links
-
Assembly
Deposited unit | ![]()
| |||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 |
| |||||||||
NMR ensembles |
|
-
Components
#1: Protein | Mass: 11882.170 Da / Num. of mol.: 1 / Fragment: N-TERMINALLY EXTENDED MODULE M5 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() |
---|
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
---|---|
NMR details | Text: 20 MM ACETATE BUFFER, NO OTHER SALTS |
-
Sample preparation
Sample conditions | pH: 4.8 / Temperature: 300 K |
---|---|
Crystal grow | *PLUS Method: other / Details: NMR |
-
Processing
Software |
| ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NMR software | Name: ![]() | ||||||||||||
NMR ensemble | Conformers submitted total number: 1 |