登録情報 | データベース: PDB / ID: 1nax |
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タイトル | Thyroid receptor beta1 in complex with a beta-selective ligand |
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要素 | Thyroid hormone receptor beta-1 |
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キーワード | MEMBRANE PROTEIN / Nuclear receptor / thyroid receptor / complex |
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機能・相同性 | 機能・相同性情報
retinal cone cell apoptotic process / negative regulation of female receptivity / female courtship behavior / retinal cone cell development / thyroid hormone receptor signaling pathway / positive regulation of thyroid hormone receptor signaling pathway / cellular response to thyroid hormone stimulus / regulation of heart contraction / type I pneumocyte differentiation / thyroid hormone binding ...retinal cone cell apoptotic process / negative regulation of female receptivity / female courtship behavior / retinal cone cell development / thyroid hormone receptor signaling pathway / positive regulation of thyroid hormone receptor signaling pathway / cellular response to thyroid hormone stimulus / regulation of heart contraction / type I pneumocyte differentiation / thyroid hormone binding / retinoic acid receptor signaling pathway / sensory perception of sound / SUMOylation of intracellular receptors / mRNA transcription by RNA polymerase II / chromatin DNA binding / transcription coactivator binding / Nuclear Receptor transcription pathway / RNA polymerase II transcription regulator complex / nuclear receptor activity / sequence-specific double-stranded DNA binding / cell differentiation / nuclear body / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / DNA-templated transcription / chromatin / enzyme binding / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / DNA binding / zinc ion binding / nucleoplasm / nucleus類似検索 - 分子機能 Thyroid hormone receptor / Retinoid X Receptor / Retinoid X Receptor / Nuclear hormone receptor / Nuclear hormones receptors DNA-binding region signature. / Zinc finger, nuclear hormone receptor-type / Zinc finger, C4 type (two domains) / Nuclear hormone receptors DNA-binding domain profile. / c4 zinc finger in nuclear hormone receptors / Nuclear hormone receptor, ligand-binding domain ...Thyroid hormone receptor / Retinoid X Receptor / Retinoid X Receptor / Nuclear hormone receptor / Nuclear hormones receptors DNA-binding region signature. / Zinc finger, nuclear hormone receptor-type / Zinc finger, C4 type (two domains) / Nuclear hormone receptors DNA-binding domain profile. / c4 zinc finger in nuclear hormone receptors / Nuclear hormone receptor, ligand-binding domain / Nuclear hormone receptor-like domain superfamily / Ligand-binding domain of nuclear hormone receptor / Nuclear receptor (NR) ligand-binding (LBD) domain profile. / Ligand binding domain of hormone receptors / Zinc finger, NHR/GATA-type / Orthogonal Bundle / Mainly Alpha類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / フーリエ合成 / 解像度: 2.7 Å |
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データ登録者 | Ye, L. / Li, Y.L. / Mellstrom, K. / Mellin, C. / Bladh, L.G. / Koehler, K. / Garg, N. / Garcia Collazo, A.M. / Litten, C. / Husman, B. ...Ye, L. / Li, Y.L. / Mellstrom, K. / Mellin, C. / Bladh, L.G. / Koehler, K. / Garg, N. / Garcia Collazo, A.M. / Litten, C. / Husman, B. / Persson, K. / Ljunggren, J. / Grover, G. / Sleph, P.G. / George, R. / Malm, J. |
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引用 | ジャーナル: J.Med.Chem. / 年: 2003 タイトル: Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1. 著者: Ye, L. / Li, Y.L. / Mellstrom, K. / Mellin, C. / Bladh, L.G. / Koehler, K. / Garg, N. / Garcia Collazo, A.M. / Litten, C. / Husman, B. / Persson, K. / Ljunggren, J. / Grover, G. / Sleph, P.G. ...著者: Ye, L. / Li, Y.L. / Mellstrom, K. / Mellin, C. / Bladh, L.G. / Koehler, K. / Garg, N. / Garcia Collazo, A.M. / Litten, C. / Husman, B. / Persson, K. / Ljunggren, J. / Grover, G. / Sleph, P.G. / George, R. / Malm, J. |
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履歴 | 登録 | 2002年11月29日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2003年6月17日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月28日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Derived calculations / Version format compliance |
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改定 1.3 | 2012年2月15日 | Group: Other |
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改定 1.4 | 2024年2月14日 | Group: Data collection / Database references / Derived calculations カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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