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Open data
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Basic information
Entry | Database: PDB / ID: 1lau | ||||||
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Title | URACIL-DNA GLYCOSYLASE | ||||||
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![]() | HYDROLASE/DNA / HYDROLASE / GLYCOSIDASE / DNA / HYDROLASE-DNA COMPLEX | ||||||
Function / homology | ![]() base-excision repair, AP site formation via deaminated base removal / uracil-DNA glycosylase / uracil DNA N-glycosylase activity / host cell nucleus Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() | ||||||
![]() | Pearl, L.H. / Savva, R. | ||||||
![]() | ![]() Title: The structural basis of specific base-excision repair by uracil-DNA glycosylase. Authors: Savva, R. / McAuley-Hecht, K. / Brown, T. / Pearl, L. #1: ![]() Title: Crystallization and Preliminary X-Ray Analysis of the Uracil-DNA Glycosylase DNA Repair Enzyme from Herpes Simplex Virus Type 1 Authors: Savva, R. / Pearl, L.H. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 62.8 KB | Display | ![]() |
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PDB format | ![]() | 45.7 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 371.5 KB | Display | ![]() |
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Full document | ![]() | 372 KB | Display | |
Data in XML | ![]() | 6.1 KB | Display | |
Data in CIF | ![]() | 9.9 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
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Links
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Assembly
Deposited unit | ![]()
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1 |
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Unit cell |
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Components
#1: DNA chain | Mass: 867.621 Da / Num. of mol.: 1 / Source method: obtained synthetically |
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#2: Protein | Mass: 27366.447 Da / Num. of mol.: 1 / Source method: isolated from a natural source Source: (natural) ![]() ![]() Genus: Simplexvirus / Strain: STRAIN 17 / References: UniProt: P10186 |
#3: Water | ChemComp-HOH / |
Compound details | THE URACIL-DNA GLYCOSYLASE MOLECULE IN THIS STUDY CONSISTS OF 244 AMINO ACIDS FROM THE METHIONINE ...THE URACIL-DNA GLYCOSYLAS |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.21 Å3/Da / Density % sol: 44.4 % | |||||||||||||||||||||||||
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Crystal grow | *PLUS pH: 6.8 / Method: unknown | |||||||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Detector | Type: MARRESEARCH / Detector: IMAGE PLATE |
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Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Relative weight: 1 |
Reflection | Num. obs: 20152 / % possible obs: 90.3 % / Redundancy: 2.1 % |
Reflection | *PLUS % possible obs: 90.3 % / Redundancy: 2.1 % |
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Processing
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Refinement | Resolution: 1.8→8 Å / σ(F): 0
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Refinement step | Cycle: LAST / Resolution: 1.8→8 Å
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Refine LS restraints |
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Software | *PLUS Name: ![]() | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement | *PLUS Highest resolution: 1.8 Å / Lowest resolution: 8 Å / σ(F): 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Solvent computation | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | *PLUS |