登録情報 | データベース: PDB / ID: 1j04 |
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タイトル | Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro |
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要素 | alanine--glyoxylate aminotransferase |
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キーワード | TRANSFERASE / Aminotransferase / Pyridoxal phosphate |
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機能・相同性 | 機能・相同性情報
oxalic acid secretion / serine-pyruvate transaminase / alanine-glyoxylate transaminase / glyoxylate metabolic process / L-alanine catabolic process / glycine biosynthetic process, by transamination of glyoxylate / L-serine-pyruvate transaminase activity / alanine-glyoxylate transaminase activity / Glyoxylate metabolism and glycine degradation / glyoxylate catabolic process ...oxalic acid secretion / serine-pyruvate transaminase / alanine-glyoxylate transaminase / glyoxylate metabolic process / L-alanine catabolic process / glycine biosynthetic process, by transamination of glyoxylate / L-serine-pyruvate transaminase activity / alanine-glyoxylate transaminase activity / Glyoxylate metabolism and glycine degradation / glyoxylate catabolic process / L-serine metabolic process / L-cysteine catabolic process / transaminase activity / amino acid binding / peroxisomal matrix / Notch signaling pathway / Peroxisomal protein import / pyridoxal phosphate binding / peroxisome / intracellular membrane-bounded organelle / protein homodimerization activity / identical protein binding / cytosol類似検索 - 分子機能 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase / Aminotransferase class-V, pyridoxal-phosphate binding site / Aminotransferases class-V pyridoxal-phosphate attachment site. / Aminotransferase class V domain / Aminotransferase class-V / Aspartate Aminotransferase, domain 1 / Aspartate Aminotransferase, domain 1 / Aspartate Aminotransferase; domain 2 / Type I PLP-dependent aspartate aminotransferase-like (Major domain) / Pyridoxal phosphate-dependent transferase, small domain ...Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase / Aminotransferase class-V, pyridoxal-phosphate binding site / Aminotransferases class-V pyridoxal-phosphate attachment site. / Aminotransferase class V domain / Aminotransferase class-V / Aspartate Aminotransferase, domain 1 / Aspartate Aminotransferase, domain 1 / Aspartate Aminotransferase; domain 2 / Type I PLP-dependent aspartate aminotransferase-like (Major domain) / Pyridoxal phosphate-dependent transferase, small domain / Pyridoxal phosphate-dependent transferase, major domain / Pyridoxal phosphate-dependent transferase / Alpha-Beta Complex / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 (AMINOOXY)ACETIC ACID / Alanine--glyoxylate aminotransferase類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.6 Å |
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データ登録者 | Zhang, X. / Djordjevic, S. / Bartlam, M. / Ye, S. / Rao, Z. / Danpure, C.J. |
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引用 | ジャーナル: Acta Crystallogr.,Sect.F / 年: 2010 タイトル: Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting. 著者: Djordjevic, S. / Zhang, X. / Bartlam, M. / Ye, S. / Rao, Z. / Danpure, C.J. |
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履歴 | 登録 | 2002年10月30日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2003年11月11日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月27日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Derived calculations / Version format compliance |
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改定 1.3 | 2018年7月25日 | Group: Data collection / Database references ...Data collection / Database references / Refinement description / Source and taxonomy / Structure summary カテゴリ: entity / entity_src_gen ...entity / entity_src_gen / entity_src_nat / software / struct_ref_seq_dif Item: _entity.src_method / _software.version |
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改定 1.4 | 2021年11月10日 | Group: Database references / Derived calculations カテゴリ: database_2 / struct_conn ...database_2 / struct_conn / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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改定 1.5 | 2023年10月25日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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改定 1.6 | 2023年11月15日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond / Item: _chem_comp_atom.atom_id / _chem_comp_bond.atom_id_2 |
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