+Open data
-Basic information
Entry | Database: PDB / ID: 1hdj | ||||||
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Title | HUMAN HSP40 (HDJ-1), NMR | ||||||
Components | HUMAN HSP40 | ||||||
Keywords | MOLECULAR CHAPERONE | ||||||
Function / homology | Function and homology information sperm head / negative regulation of inclusion body assembly / positive regulation of ATP-dependent activity / transcription regulator inhibitor activity / ATPase activator activity / chaperone cofactor-dependent protein refolding / HSF1-dependent transactivation / response to unfolded protein / Regulation of HSF1-mediated heat shock response / Attenuation phase ...sperm head / negative regulation of inclusion body assembly / positive regulation of ATP-dependent activity / transcription regulator inhibitor activity / ATPase activator activity / chaperone cofactor-dependent protein refolding / HSF1-dependent transactivation / response to unfolded protein / Regulation of HSF1-mediated heat shock response / Attenuation phase / regulation of cellular response to heat / forebrain development / protein folding chaperone / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / Hsp70 protein binding / MAPK6/MAPK4 signaling / transcription corepressor activity / unfolded protein binding / protein-folding chaperone binding / cellular response to heat / ATPase binding / dendritic spine / postsynaptic density / cadherin binding / neuronal cell body / glutamatergic synapse / nucleolus / negative regulation of transcription by RNA polymerase II / extracellular exosome / nucleoplasm / nucleus / cytosol / cytoplasm Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Qian, Y.Q. / Patel, D. / Hartl, F.-U. / Mccoll, D.J. | ||||||
Citation | Journal: J.Mol.Biol. / Year: 1996 Title: Nuclear magnetic resonance solution structure of the human Hsp40 (HDJ-1) J-domain. Authors: Qian, Y.Q. / Patel, D. / Hartl, F.U. / McColl, D.J. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1hdj.cif.gz | 474 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1hdj.ent.gz | 398.1 KB | Display | PDB format |
PDBx/mmJSON format | 1hdj.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/hd/1hdj ftp://data.pdbj.org/pub/pdb/validation_reports/hd/1hdj | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 8918.938 Da / Num. of mol.: 1 / Fragment: J-DOMAIN Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Production host: Escherichia coli (E. coli) / References: UniProt: P25685 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Sample conditions | pH: 5.8 / Temperature: 303 K |
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Crystal grow | *PLUS Method: other / Details: NMR |
-Processing
Software | Name: AMBER / Classification: refinement |
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NMR software | Name: DIANA / Developer: GUNTERT,BRAUN,WUTHRICH / Classification: refinement |
NMR ensemble | Conformers submitted total number: 20 |