- PDB-1fzq: CRYSTAL STRUCTURE OF MURINE ARL3-GDP -
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Basic information
Entry
Database: PDB / ID: 1fzq
Title
CRYSTAL STRUCTURE OF MURINE ARL3-GDP
Components
ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3
Keywords
SIGNALING PROTEIN / Protein-GDP complex without magnesium / ARF family / Ras Superfamily / G-domain
Function / homology
Function and homology information
Trafficking of myristoylated proteins to the cilium / photoreceptor cell development / protein localization to ciliary membrane / intraciliary transport / post-Golgi vesicle-mediated transport / ciliary transition zone / photoreceptor connecting cilium / Golgi to plasma membrane transport / smoothened signaling pathway / small GTPase-mediated signal transduction ...Trafficking of myristoylated proteins to the cilium / photoreceptor cell development / protein localization to ciliary membrane / intraciliary transport / post-Golgi vesicle-mediated transport / ciliary transition zone / photoreceptor connecting cilium / Golgi to plasma membrane transport / smoothened signaling pathway / small GTPase-mediated signal transduction / cytoplasmic microtubule / axoneme / mitotic cytokinesis / cilium assembly / ciliary basal body / kidney development / spindle microtubule / cilium / GDP binding / microtubule cytoskeleton / protein transport / midbody / microtubule binding / Golgi membrane / GTPase activity / centrosome / GTP binding / Golgi apparatus / magnesium ion binding / nucleoplasm / nucleus / cytoplasm Similarity search - Function
ADP-ribosylation factor-like protein 2/3 / small GTPase Arf family profile. / Sar1p-like members of the Ras-family of small GTPases / Small GTPase superfamily, ARF/SAR type / ADP-ribosylation factor family / ARF-like small GTPases; ARF, ADP-ribosylation factor / Rab subfamily of small GTPases / Small GTP-binding protein domain / P-loop containing nucleotide triphosphate hydrolases / P-loop containing nucleoside triphosphate hydrolase ...ADP-ribosylation factor-like protein 2/3 / small GTPase Arf family profile. / Sar1p-like members of the Ras-family of small GTPases / Small GTPase superfamily, ARF/SAR type / ADP-ribosylation factor family / ARF-like small GTPases; ARF, ADP-ribosylation factor / Rab subfamily of small GTPases / Small GTP-binding protein domain / P-loop containing nucleotide triphosphate hydrolases / P-loop containing nucleoside triphosphate hydrolase / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homology
The biological active unit is most probably a monomer. The electron density map showed a disulphide bridge between Cys 118 and a symmetry-related Cys 118 of a crystal neighbour. This is considered to be a crystallization artefact and was not included in the model.
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Components
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Protein , 1 types, 1 molecules A
#1: Protein
ADP-RIBOSYLATIONFACTOR-LIKEPROTEIN3 / ARF-LIKE PROTEIN 3 / ARL3
Mass: 20380.307 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Mus musculus (house mouse) / Plasmid: PET21D / Production host: Escherichia coli (E. coli) / References: UniProt: Q9WUL7
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