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Open data
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Basic information
Entry | Database: PDB / ID: 1feo | ||||||
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Title | Solution structure of omega-conotoxin MVIIA with C-terminal Gly | ||||||
![]() | OMEGA-CONOTOXIN MVIIA-GLY | ||||||
![]() | TOXIN / beta sheet / disulfide knot | ||||||
Function / homology | ![]() host cell presynaptic membrane / ion channel inhibitor activity / calcium channel regulator activity / toxin activity / extracellular region Similarity search - Function | ||||||
Method | SOLUTION NMR / simulated annealing in torsion angle space | ||||||
![]() | Goldenberg, D.P. / Koehn, R.E. / Gilbert, D.E. / Wagner, G. | ||||||
![]() | ![]() Title: Solution structure and backbone dynamics of an omega-conotoxin precursor Authors: Goldenberg, D.P. / Koehn, R.E. / Gilbert, D.E. / Wagner, G. #1: ![]() Title: Folding of omega-conotoxins. 2. Influence of precursor sequences and protein disulfide isomerase Authors: Price-Carter, M. / Gray, W.R. / Goldenberg, D.P. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 121.8 KB | Display | ![]() |
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PDB format | ![]() | 101.7 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 346.4 KB | Display | ![]() |
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Full document | ![]() | 458.6 KB | Display | |
Data in XML | ![]() | 10.6 KB | Display | |
Data in CIF | ![]() | 16.5 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: Protein/peptide | Mass: 2709.268 Da / Num. of mol.: 1 / Source method: obtained synthetically Details: Chemically synthesized sequence based on c-DNA from Conus magus. 15N-labeled sample was produced in Escherichia coli using a synthetic gene. References: UniProt: P05484 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||
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NMR experiment |
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Sample preparation
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Sample conditions | pH: 6.0 / Pressure: ambient / Temperature: 283 K | |||||||||
Crystal grow | *PLUS Method: other / Details: NMR |
-NMR measurement
NMR spectrometer |
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Processing
NMR software |
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Refinement | Method: simulated annealing in torsion angle space / Software ordinal: 1 Details: The structures are based on 249 non-reduncant NOE-derived distance restraints, 9 distance restraints from the three disulfide bonds, 16 distance restraints from hydrogen bonds, 19 dihedral angle restraints. | ||||||||||||||||||||
NMR representative | Selection criteria: closest to the average | ||||||||||||||||||||
NMR ensemble | Conformer selection criteria: target function / Conformers calculated total number: 50 / Conformers submitted total number: 20 |