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- PDB-1e8t: Structure of the multifunctional paramyxovirus hemagglutinin-neur... -
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Open data
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Basic information
Entry | Database: PDB / ID: 1e8t | |||||||||
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Title | Structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase | |||||||||
![]() | HEMAGGLUTININ-NEURAMINIDASE | |||||||||
![]() | HYDROLASE / SIALIDASE / NEURAMINIDASE / HEMAGGLUTININ | |||||||||
Function / homology | ![]() exo-alpha-(2->3)-sialidase activity / exo-alpha-(2->6)-sialidase activity / exo-alpha-(2->8)-sialidase activity / exo-alpha-sialidase / host cell surface receptor binding / symbiont entry into host cell / viral envelope / virion attachment to host cell / host cell plasma membrane / virion membrane / membrane Similarity search - Function | |||||||||
Biological species | ![]() | |||||||||
Method | ![]() ![]() ![]() | |||||||||
![]() | Crennell, S. / Takimoto, T. / Portner, A. / Taylor, G. | |||||||||
![]() | ![]() Title: Crystal Structure of the Multifunctional Paramyxovirus Hemagglutinin-Neuraminidase Authors: Crennell, S. / Takimoto, T. / Portner, A. / Taylor, G. #1: Journal: Virology / Year: 2000 Title: Crystallization of Newcastle Disease Virus Hemagglutinin-Neuraminidase Glycoprotein Authors: Takimoto, T. / Taylor, G.L. / Crennell, S.J. / Scroggs, R.A. / Portner, A. | |||||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 183.8 KB | Display | ![]() |
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PDB format | ![]() | 149.4 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 516.2 KB | Display | ![]() |
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Full document | ![]() | 534.7 KB | Display | |
Data in XML | ![]() | 20.6 KB | Display | |
Data in CIF | ![]() | 31.5 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
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Links
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Assembly
Deposited unit | ![]()
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1 |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS oper: (Code: given Matrix: (-0.9883, 0.1475, -0.0389), Vector: |
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Components
-Protein , 1 types, 2 molecules AB
#1: Protein | Mass: 49856.910 Da / Num. of mol.: 2 / Fragment: HEAD DOMAIN, RESIDUES 124-577 / Source method: isolated from a natural source / Source: (natural) ![]() |
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-Sugars , 2 types, 3 molecules ![](data/chem/img/NAG.gif)
#2: Polysaccharide | Source method: isolated from a genetically manipulated source #5: Sugar | ChemComp-NAG / | |
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-Non-polymers , 3 types, 215 molecules ![](data/chem/img/CA.gif)
![](data/chem/img/GOL.gif)
![](data/chem/img/HOH.gif)
![](data/chem/img/GOL.gif)
![](data/chem/img/HOH.gif)
#3: Chemical | ChemComp-CA / | ||
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#4: Chemical | #6: Water | ChemComp-HOH / | |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.78 Å3/Da / Density % sol: 55.69 % | ||||||||||||||||||||
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Crystal grow | pH: 4.6 / Details: pH 4.60 | ||||||||||||||||||||
Crystal grow | *PLUS Method: vapor diffusion, hanging drop | ||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() ![]() ![]() ![]() ![]() |
Detector | Detector: IMAGE PLATE |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 0.992 Å / Relative weight: 1 |
Reflection | Resolution: 2.5→30 Å / Num. obs: 38168 / % possible obs: 97 % / Redundancy: 11 % / Rmerge(I) obs: 0.031 / Rsym value: 0.031 |
Reflection | *PLUS Num. measured all: 420703 |
Reflection shell | *PLUS % possible obs: 96 % / Rmerge(I) obs: 0.073 |
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Processing
Software | Name: CNS / Classification: refinement | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Refinement | Method to determine structure: ![]()
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Refinement step | Cycle: LAST / Resolution: 2.5→6 Å
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Refine LS restraints |
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