登録情報 データベース : PDB / ID : 1cee 構造の表示 ダウンロードとリンクタイトル SOLUTION STRUCTURE OF CDC42 IN COMPLEX WITH THE GTPASE BINDING DOMAIN OF WASP 要素GTP-BINDING RHO-LIKE PROTEIN WISKOTT-ALDRICH SYNDROME PROTEIN WASP 詳細キーワード Structural protein Regulation / CDC42 ACTIN REGULATOR GTPASE AND THE GTPASE BINDING DOMAIN OF ITS EFFECTOR WASP機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
regulation of T cell antigen processing and presentation / Cdc42 protein signal transduction / GBD domain binding / Golgi transport complex / positive regulation of pinocytosis / regulation of actin polymerization or depolymerization / dendritic cell migration / endothelin receptor signaling pathway involved in heart process / GTPase regulator activity / cardiac neural crest cell migration involved in outflow tract morphogenesis ... regulation of T cell antigen processing and presentation / Cdc42 protein signal transduction / GBD domain binding / Golgi transport complex / positive regulation of pinocytosis / regulation of actin polymerization or depolymerization / dendritic cell migration / endothelin receptor signaling pathway involved in heart process / GTPase regulator activity / cardiac neural crest cell migration involved in outflow tract morphogenesis / storage vacuole / positive regulation of epithelial cell proliferation involved in lung morphogenesis / apolipoprotein A-I receptor binding / neuron fate determination / organelle transport along microtubule / regulation of attachment of spindle microtubules to kinetochore / positive regulation of pseudopodium assembly / Inactivation of CDC42 and RAC1 / actin filament-based movement / cardiac conduction system development / host-mediated perturbation of viral process / regulation of filopodium assembly / leading edge membrane / neuropilin signaling pathway / establishment of Golgi localization / negative regulation of cell motility / adherens junction organization / GTP-dependent protein binding / cell junction assembly / filopodium assembly / establishment of epithelial cell apical/basal polarity / dendritic spine morphogenesis / actin polymerization or depolymerization / thioesterase binding / regulation of lamellipodium assembly / regulation of stress fiber assembly / embryonic heart tube development / RHO GTPases activate KTN1 / DCC mediated attractive signaling / vesicle membrane / regulation of postsynapse organization / CD28 dependent Vav1 pathway / negative regulation of stress fiber assembly / Wnt signaling pathway, planar cell polarity pathway / endosomal transport / positive regulation of filopodium assembly / regulation of mitotic nuclear division / phagocytosis, engulfment / nuclear migration / RHOV GTPase cycle / small GTPase-mediated signal transduction / Myogenesis / heart contraction / positive regulation of cytokinesis / establishment of cell polarity / establishment or maintenance of cell polarity / RHOJ GTPase cycle / Golgi organization / RHOQ GTPase cycle / RHO GTPases activate PAKs / RHOU GTPase cycle / CDC42 GTPase cycle / Generation of second messenger molecules / macrophage differentiation / RHOG GTPase cycle / RHO GTPases Activate WASPs and WAVEs / epidermis development / RAC2 GTPase cycle / RAC3 GTPase cycle / spindle midzone / RHO GTPases activate IQGAPs / negative regulation of protein-containing complex assembly / positive regulation of double-strand break repair via homologous recombination / phospholipase binding / positive regulation of lamellipodium assembly / GPVI-mediated activation cascade / phagocytic vesicle / positive regulation of stress fiber assembly / actin filament polymerization / EPHB-mediated forward signaling / RAC1 GTPase cycle / substantia nigra development / positive regulation of substrate adhesion-dependent cell spreading / Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation / T cell activation / actin filament organization / small monomeric GTPase / integrin-mediated signaling pathway / filopodium / actin filament / regulation of actin cytoskeleton organization / FCGR3A-mediated phagocytosis / EGFR downregulation / RHO GTPases Activate Formins / defense response / MAPK6/MAPK4 signaling / Regulation of actin dynamics for phagocytic cup formation / SH3 domain binding / cellular response to type II interferon / small GTPase binding 類似検索 - 分子機能 SerineThreonine-protein kinase PAK-alpha; Chain A / CRIB domain / Actin nucleation-promoting factor WAS, C-terminal / WASP family, EVH1 domain / Cdc42 / Wiskott Aldrich syndrome homology region 2 / WH2 motif / WH1/EVH1 domain / WH1 domain / WH1 domain profile. ... SerineThreonine-protein kinase PAK-alpha; Chain A / CRIB domain / Actin nucleation-promoting factor WAS, C-terminal / WASP family, EVH1 domain / Cdc42 / Wiskott Aldrich syndrome homology region 2 / WH2 motif / WH1/EVH1 domain / WH1 domain / WH1 domain profile. / WASP homology region 1 / WH2 domain / WH2 domain profile. / CRIB domain superfamily / P21-Rho-binding domain / CRIB domain profile. / P21-Rho-binding domain / CRIB domain / Small GTPase Rho / Small GTPase Rho domain profile. / Rho (Ras homology) subfamily of Ras-like small GTPases / Ras subfamily of RAS small GTPases / Small GTPase / Ras family / Rab subfamily of small GTPases / Small GTP-binding protein domain / PH-like domain superfamily / P-loop containing nucleotide triphosphate hydrolases / Alpha-Beta Complex / Rossmann fold / P-loop containing nucleoside triphosphate hydrolase / 3-Layer(aba) Sandwich / Alpha Beta 類似検索 - ドメイン・相同性 PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER / Actin nucleation-promoting factor WAS / Cell division control protein 42 homolog 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 溶液NMR / SIMULATED ANNEALING , TORSION ANGLE DYNAMICS 詳細データ登録者 Abdul-Manan, N. / Aghazadeh, B. / Liu, G.A. / Majumdar, A. / Ouerfelli, O. / Rosen, M.K. 引用ジャーナル : Nature / 年 : 1999タイトル : Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein.著者 : Abdul-Manan, N. / Aghazadeh, B. / Liu, G.A. / Majumdar, A. / Ouerfelli, O. / Siminovitch, K.A. / Rosen, M.K. 履歴 登録 1999年3月8日 登録サイト : BNL / 処理サイト : RCSB改定 1.0 1999年6月30日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月26日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2022年2月16日 Group : Data collection / Database references / Derived calculationsカテゴリ : database_2 / pdbx_nmr_software ... database_2 / pdbx_nmr_software / pdbx_struct_assembly / pdbx_struct_oper_list / struct_conn / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id 改定 1.4 2023年12月27日 Group : Data collection / カテゴリ : chem_comp_atom / chem_comp_bond
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