+データを開く
-基本情報
登録情報 | データベース: PDB / ID: 1bo9 | ||||||
---|---|---|---|---|---|---|---|
タイトル | NMR SOLUTION STRUCTURE OF DOMAIN 1 OF HUMAN ANNEXIN I | ||||||
要素 | PROTEIN (ANNEXIN I) | ||||||
キーワード | METAL TRANSPORT / DOMAIN 1 | ||||||
機能・相同性 | 機能・相同性情報 regulation of interleukin-1 production / myoblast migration involved in skeletal muscle regeneration / regulation of leukocyte migration / granulocyte chemotaxis / positive regulation of T-helper 1 cell differentiation / phospholipase A2 inhibitor activity / regulation of hormone secretion / positive regulation of vesicle fusion / neutrophil clearance / negative regulation of T-helper 2 cell differentiation ...regulation of interleukin-1 production / myoblast migration involved in skeletal muscle regeneration / regulation of leukocyte migration / granulocyte chemotaxis / positive regulation of T-helper 1 cell differentiation / phospholipase A2 inhibitor activity / regulation of hormone secretion / positive regulation of vesicle fusion / neutrophil clearance / negative regulation of T-helper 2 cell differentiation / negative regulation of interleukin-8 production / positive regulation of neutrophil apoptotic process / neutrophil activation / cadherin binding involved in cell-cell adhesion / peptide cross-linking / cornified envelope / neutrophil homeostasis / calcium-dependent phospholipid binding / Formyl peptide receptors bind formyl peptides and many other ligands / motile cilium / cellular response to glucocorticoid stimulus / negative regulation of exocytosis / vesicle membrane / alpha-beta T cell differentiation / arachidonate secretion / positive regulation of cell migration involved in sprouting angiogenesis / positive regulation of wound healing / phosphatidylserine binding / monocyte chemotaxis / phagocytic cup / G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger / Smooth Muscle Contraction / lateral plasma membrane / cellular response to vascular endothelial growth factor stimulus / positive regulation of G1/S transition of mitotic cell cycle / phagocytosis / positive regulation of T cell proliferation / keratinocyte differentiation / positive regulation of interleukin-2 production / adherens junction / sarcolemma / phospholipid binding / calcium-dependent protein binding / regulation of cell shape / regulation of inflammatory response / early endosome membrane / G alpha (i) signalling events / actin cytoskeleton organization / basolateral plasma membrane / Interleukin-4 and Interleukin-13 signaling / G alpha (q) signalling events / collagen-containing extracellular matrix / vesicle / adaptive immune response / cell surface receptor signaling pathway / endosome / inflammatory response / apical plasma membrane / innate immune response / signaling receptor binding / focal adhesion / lipid binding / calcium ion binding / negative regulation of apoptotic process / cell surface / signal transduction / extracellular space / extracellular exosome / extracellular region / nucleoplasm / nucleus / plasma membrane / cytosol / cytoplasm 類似検索 - 分子機能 | ||||||
生物種 | Homo sapiens (ヒト) | ||||||
手法 | 溶液NMR / distance geometry | ||||||
データ登録者 | Gao, J. / Yan Li, H. | ||||||
引用 | ジャーナル: J.Biol.Chem. / 年: 1999 タイトル: NMR solution structure of domain 1 of human annexin I shows an autonomous folding unit. 著者: Gao, J. / Li, Y. / Yan, H. | ||||||
履歴 |
|
-構造の表示
構造ビューア | 分子: MolmilJmol/JSmol |
---|
-ダウンロードとリンク
-ダウンロード
PDBx/mmCIF形式 | 1bo9.cif.gz | 473.6 KB | 表示 | PDBx/mmCIF形式 |
---|---|---|---|---|
PDB形式 | pdb1bo9.ent.gz | 397 KB | 表示 | PDB形式 |
PDBx/mmJSON形式 | 1bo9.json.gz | ツリー表示 | PDBx/mmJSON形式 | |
その他 | その他のダウンロード |
-検証レポート
文書・要旨 | 1bo9_validation.pdf.gz | 342.9 KB | 表示 | wwPDB検証レポート |
---|---|---|---|---|
文書・詳細版 | 1bo9_full_validation.pdf.gz | 504 KB | 表示 | |
XML形式データ | 1bo9_validation.xml.gz | 30.3 KB | 表示 | |
CIF形式データ | 1bo9_validation.cif.gz | 48.1 KB | 表示 | |
アーカイブディレクトリ | https://data.pdbj.org/pub/pdb/validation_reports/bo/1bo9 ftp://data.pdbj.org/pub/pdb/validation_reports/bo/1bo9 | HTTPS FTP |
-関連構造データ
-リンク
-集合体
登録構造単位 |
| |||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 |
| |||||||||
NMR アンサンブル |
|
-要素
#1: タンパク質 | 分子量: 8023.305 Da / 分子数: 1 / 断片: DOMAIN 1 / 由来タイプ: 組換発現 / 由来: (組換発現) Homo sapiens (ヒト) / 生物種 (発現宿主): Escherichia coli / 発現宿主: Escherichia coli BL21(DE3) (大腸菌) / 株 (発現宿主): BL21(DE3) / 参照: UniProt: P04083 |
---|
-実験情報
-実験
実験 | 手法: 溶液NMR |
---|---|
NMR実験 | タイプ: NOESY |
NMR実験の詳細 | Text: THE STRUCTURE WAS DETERMINED USING TRIPLE-RESONANCE NMR SPECTROSCOPY ON 13C, 15N-LABELED PROTEIN. |
-試料調製
試料状態 | pH: 7 / 圧: 1 atm / 温度: 300 K |
---|---|
結晶化 | *PLUS 手法: other / 詳細: NMR |
-NMR測定
NMRスペクトロメーター | タイプ: Bruker DMX600 / 製造業者: Bruker / モデル: DMX600 / 磁場強度: 600 MHz |
---|
-解析
NMR software |
| ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
精密化 | 手法: distance geometry / ソフトェア番号: 1 / 詳細: DG/SA | ||||||||||||
NMRアンサンブル | コンフォーマー選択の基準: LEAST RESTRAINT VIOLATION 計算したコンフォーマーの数: 50 / 登録したコンフォーマーの数: 21 |