登録情報 データベース : PDB / ID : 1bet 構造の表示 ダウンロードとリンクタイトル NEW PROTEIN FOLD REVEALED BY A 2.3 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF NERVE GROWTH FACTOR 要素BETA-NERVE GROWTH FACTOR 詳細 キーワード GROWTH FACTOR機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
TRKA activation by NGF / NFG and proNGF binds to p75NTR / NADE modulates death signalling / NGF processing / Axonal growth stimulation / Frs2-mediated activation / negative regulation of type B pancreatic cell apoptotic process / positive regulation of neurotrophin TRK receptor signaling pathway / PI3K/AKT activation / ARMS-mediated activation ... TRKA activation by NGF / NFG and proNGF binds to p75NTR / NADE modulates death signalling / NGF processing / Axonal growth stimulation / Frs2-mediated activation / negative regulation of type B pancreatic cell apoptotic process / positive regulation of neurotrophin TRK receptor signaling pathway / PI3K/AKT activation / ARMS-mediated activation / nerve growth factor receptor binding / NRIF signals cell death from the nucleus / p75NTR recruits signalling complexes / Retrograde neurotrophin signalling / NF-kB is activated and signals survival / metalloendopeptidase inhibitor activity / positive regulation of neuron maturation / nerve growth factor signaling pathway / regulation of neurotransmitter secretion / nerve development / positive regulation of collateral sprouting / peripheral nervous system development / regulation of release of sequestered calcium ion into cytosol / axon extension / positive regulation of Ras protein signal transduction / regulation of neuron differentiation / positive regulation of DNA binding / transmembrane receptor protein tyrosine kinase activator activity / positive regulation of stem cell proliferation / positive regulation of axon extension / extrinsic apoptotic signaling pathway in absence of ligand / positive regulation of protein autophosphorylation / cell surface receptor protein tyrosine kinase signaling pathway / sensory perception of pain / positive regulation of neuron differentiation / adult locomotory behavior / neuron projection morphogenesis / positive regulation of protein ubiquitination / endosome lumen / growth factor activity / modulation of chemical synaptic transmission / memory / positive regulation of neuron projection development / circadian rhythm / neuron projection development / synaptic vesicle / positive regulation of peptidyl-serine phosphorylation / positive regulation of cell growth / neuron apoptotic process / negative regulation of neuron apoptotic process / positive regulation of ERK1 and ERK2 cascade / positive regulation of protein phosphorylation / endoplasmic reticulum lumen / axon / lipid binding / dendrite / positive regulation of cell population proliferation / positive regulation of gene expression / extracellular space / extracellular region 類似検索 - 分子機能 Nerve growth factor, beta subunit, mammalian / Nerve growth factor, beta subunit / Nerve growth factor family profile. / Nerve growth factor-related / Nerve growth factor conserved site / Nerve growth factor-like / Nerve growth factor family / Nerve growth factor family signature. / Nerve growth factor (NGF or beta-NGF) / Cystine Knot Cytokines, subunit B ... Nerve growth factor, beta subunit, mammalian / Nerve growth factor, beta subunit / Nerve growth factor family profile. / Nerve growth factor-related / Nerve growth factor conserved site / Nerve growth factor-like / Nerve growth factor family / Nerve growth factor family signature. / Nerve growth factor (NGF or beta-NGF) / Cystine Knot Cytokines, subunit B / Cystine-knot cytokines / Cystine-knot cytokine / Ribbon / Mainly Beta 類似検索 - ドメイン・相同性生物種 Mus musculus (ハツカネズミ)手法 X線回折 / 解像度 : 2.3 Å 詳細データ登録者 Mcdonald, N.Q. / Lapatto, R. / Murray-Rust, J. / Gunning, J. / Wlodawer, A. / Blundell, T.L. 引用ジャーナル : Nature / 年 : 1991タイトル : New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor.著者 : McDonald, N.Q. / Lapatto, R. / Murray-Rust, J. / Gunning, J. / Wlodawer, A. / Blundell, T.L. 履歴 登録 1993年4月8日 処理サイト : BNL改定 1.0 1994年5月31日 Provider : repository / タイプ : Initial release改定 1.1 2008年3月24日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Derived calculations / Version format compliance改定 1.3 2024年6月5日 Group : Data collection / Database references / Otherカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.process_site
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