[English] 日本語
Yorodumi
- EMDB-36109: Cryo-EM composite map of Euglena gracilis complex I, NADH state -

+
Open data


ID or keywords:

Loading...

-
Basic information

Entry
Database: EMDB / ID: EMD-36109
TitleCryo-EM composite map of Euglena gracilis complex I, NADH state
Map data
Sample
  • Complex: Euglena gracilis respiratory complex I, NADH state
    • Protein or peptide: x 58 types
  • Protein or peptide: x 1 types
  • Ligand: x 12 types
KeywordsElectron transport chain / respiratory complex / membrane protein / Euglena gracilis / ELECTRON TRANSPORT
Function / homologyNADH:ubiquinone reductase (H+-translocating) / NADH:ubiquinone oxidoreductase / NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit / Proton-conducting membrane transporter / NADH dehydrogenase (ubiquinone) activity / ATP synthesis coupled electron transport / respirasome / mitochondrial membrane / NADH-ubiquinone oxidoreductase chain 4
Function and homology information
Biological speciesEuglena gracilis (euglena)
Methodsingle particle reconstruction / cryo EM / Resolution: 3.03 Å
AuthorsWu MC / He ZX / Tian HT / Hu YQ / Han FZ / Zhou L
Funding support China, 1 items
OrganizationGrant numberCountry
Other governmentZJU100 Young Professor China
CitationJournal: Nat Commun / Year: 2024
Title: Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism.
Authors: Zhaoxiang He / Mengchen Wu / Hongtao Tian / Liangdong Wang / Yiqi Hu / Fangzhu Han / Jiancang Zhou / Yong Wang / Long Zhou /
Abstract: Euglena gracilis, a model organism of the eukaryotic supergroup Discoba harbouring also clinically important parasitic species, possesses diverse metabolic strategies and an atypical electron ...Euglena gracilis, a model organism of the eukaryotic supergroup Discoba harbouring also clinically important parasitic species, possesses diverse metabolic strategies and an atypical electron transport chain. While structures of the electron transport chain complexes and supercomplexes of most other eukaryotic clades have been reported, no similar structure is currently available for Discoba, limiting the understandings of its core metabolism and leaving a gap in the evolutionary tree of eukaryotic bioenergetics. Here, we report high-resolution cryo-EM structures of Euglena's respirasome I + III + IV and supercomplex III + IV. A previously unreported fatty acid synthesis domain locates on the tip of complex I's peripheral arm, providing a clear picture of its atypical subunit composition identified previously. Individual complexes are re-arranged in the respirasome to adapt to the non-uniform membrane curvature of the discoidal cristae. Furthermore, Euglena's conformationally rigid complex I is deactivated by restricting ubiquinone's access to its substrate tunnel. Our findings provide structural insights for therapeutic developments against euglenozoan parasite infections.
History
DepositionMay 3, 2023-
Header (metadata) releaseFeb 28, 2024-
Map releaseFeb 28, 2024-
UpdateMar 13, 2024-
Current statusMar 13, 2024Processing site: PDBc / Status: Released

-
Structure visualization

Supplemental images

emd_36109.png

Downloads & links

-
Map

FileDownload / File: emd_36109.map.gz / Format: CCP4 / Size: 421.9 MB / Type: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
Voxel sizeX=Y=Z: 0.93 Å
Density
Contour LevelBy AUTHOR: 5.0
Minimum - Maximum-19.552910000000001 - 41.632266999999999
Average (Standard dev.)0.0012940549 (±0.9925682)
SymmetrySpace group: 1
Details

EMDB XML:

Map geometry
Axis orderZYX
Origin000
Dimensions480480480
Spacing480480480
CellA=B=C: 446.4 Å
α=β=γ: 90.0 °

-
Supplemental data

-
Half map: #2

Fileemd_36109_half_map_1.map
Projections & Slices
AxesZYX

Projections

Slices (1/2)
Density Histograms

Histogram

Histogram (log scale)

-
Half map: #1

Fileemd_36109_half_map_2.map
Projections & Slices
AxesZYX

Projections

Slices (1/2)
Density Histograms

Histogram

Histogram (log scale)

-
Sample components

+
Entire : Euglena gracilis respiratory complex I, NADH state

EntireName: Euglena gracilis respiratory complex I, NADH state
Components
  • Complex: Euglena gracilis respiratory complex I, NADH state
    • Protein or peptide: NDUFS1A
    • Protein or peptide: NDUFS1B
    • Protein or peptide: ND2B
    • Protein or peptide: ND4L
    • Protein or peptide: NDUFA1NADH dehydrogenase (ubiquinone), alpha 1
    • Protein or peptide: NDUFA2
    • Protein or peptide: NDUFA3
    • Protein or peptide: NDUFA5
    • Protein or peptide: NDUFA6
    • Protein or peptide: NDUFA7
    • Protein or peptide: NDUFA8
    • Protein or peptide: NDUFA9
    • Protein or peptide: NDUFAB1-alpha
    • Protein or peptide: NDUFAB1-beta
    • Protein or peptide: NDUFA12
    • Protein or peptide: NDUFA13
    • Protein or peptide: NDUFA11
    • Protein or peptide: NDUFB2
    • Protein or peptide: NDUFB3
    • Protein or peptide: NDUFB4
    • Protein or peptide: NDUFB5
    • Protein or peptide: NDUFB6
    • Protein or peptide: NDUFB7
    • Protein or peptide: NDUFB8
    • Protein or peptide: NDUFB9
    • Protein or peptide: NDUFB10
    • Protein or peptide: NDUFB11
    • Protein or peptide: NDUFC2
    • Protein or peptide: NDUEG1
    • Protein or peptide: NDUEG2
    • Protein or peptide: NDUEG3
    • Protein or peptide: NDUEG4
    • Protein or peptide: NDUEG5
    • Protein or peptide: NDUEG6
    • Protein or peptide: NDUEG8
    • Protein or peptide: NDUEG10
    • Protein or peptide: NDUEG11
    • Protein or peptide: NDUEG12
    • Protein or peptide: NDUEG13
    • Protein or peptide: NDUFX
    • Protein or peptide: NDUCA1
    • Protein or peptide: NDUCA2
    • Protein or peptide: NDUCA3
    • Protein or peptide: ND1
    • Protein or peptide: ND2A
    • Protein or peptide: ND3
    • Protein or peptide: NADH-ubiquinone oxidoreductase chain 4
    • Protein or peptide: ND5
    • Protein or peptide: NDUFS2
    • Protein or peptide: NDUFS3
    • Protein or peptide: NDUFS4
    • Protein or peptide: NDUFS5
    • Protein or peptide: NDUFS6
    • Protein or peptide: NDUFS7
    • Protein or peptide: NDUFS8
    • Protein or peptide: NDUFV1
    • Protein or peptide: NDUFV2
    • Protein or peptide: NDUEG7
  • Protein or peptide: UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK
  • Ligand: FE2/S2 (INORGANIC) CLUSTER
  • Ligand: IRON/SULFUR CLUSTERIron–sulfur cluster
  • Ligand: POTASSIUM IONPotassium
  • Ligand: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • Ligand: CARDIOLIPIN
  • Ligand: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
  • Ligand: S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate
  • Ligand: 1,2-Distearoyl-sn-glycerophosphoethanolamine
  • Ligand: UBIQUINONE-10Coenzyme Q10
  • Ligand: ZINC ION
  • Ligand: FLAVIN MONONUCLEOTIDE
  • Ligand: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE

+
Supramolecule #1: Euglena gracilis respiratory complex I, NADH state

SupramoleculeName: Euglena gracilis respiratory complex I, NADH state / type: complex / ID: 1 / Parent: 0 / Macromolecule list: #1-#55, #57-#59
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 1.5 MDa

+
Macromolecule #1: NDUFS1A

MacromoleculeName: NDUFS1A / type: protein_or_peptide / ID: 1 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 43.888836 KDa
SequenceString: MRRVLARFGP HVPRSFHTTV SRLQEAVPAS ILNAPVGLQP SQTVTCWIDH ILCEFQYPAD ITVFELARRN GINIPHFCYN RNLPIAGNC RMCMCHRVSD KKYAIACNEI AEPNAKYITV DDNLKNIRQY ILEFILANHS LDCPICDQGG ECDLQDLAEL Y GYDTSRYD ...String:
MRRVLARFGP HVPRSFHTTV SRLQEAVPAS ILNAPVGLQP SQTVTCWIDH ILCEFQYPAD ITVFELARRN GINIPHFCYN RNLPIAGNC RMCMCHRVSD KKYAIACNEI AEPNAKYITV DDNLKNIRQY ILEFILANHS LDCPICDQGG ECDLQDLAEL Y GYDTSRYD YSDIKHEPDD MPINFLIKSD MNRCIHCTKC VRFLDNFSDD GKEGELGLMG RDPQTICVFR DDGNPQSYVA DI LSANVIE ICPVGALTGR ETNHETRPWE ITRLDAINIF DGTLSAINVE VKEGTELYRV NASKDPQNPD MLLNNEFITD RAR EAPQGN EFKRMTANYA ISLDNKKLLL HHALRLYAID PLFRSKALFL LADIMNEDRH LPETKQLGH

+
Macromolecule #2: NDUFS1B

MacromoleculeName: NDUFS1B / type: protein_or_peptide / ID: 2 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 59.671816 KDa
SequenceString: MASGSEVLRQ FLTIRKNSYK YAPAFQRLHA LVNGANSAAK LRARHQKRLG INVVLGEKSD LGLCQLADTL ADRLKLADLG VSARPAKSP AVYYGHLAAQ QHRYAVPSEL KYTESSYSSR NVYIWLWTDV QQEAPDLHTQ IFTGPTSNCN VYSFGHVHNA R AGVKPVGG ...String:
MASGSEVLRQ FLTIRKNSYK YAPAFQRLHA LVNGANSAAK LRARHQKRLG INVVLGEKSD LGLCQLADTL ADRLKLADLG VSARPAKSP AVYYGHLAAQ QHRYAVPSEL KYTESSYSSR NVYIWLWTDV QQEAPDLHTQ IFTGPTSNCN VYSFGHVHNA R AGVKPVGG MEEFVGWLEG RTNLFSRTPK LETRLSNVYV LYSDNFLEMF PTNYGDIFKK IEELLGDQTF VSFSYLSRHP VS YNAVQTY AFPPVTQLLK RNDQYRLNVL TNVQRQDYSE NESRGRFTAR LMCHSTLLRA DQPMNELVIA QKTPAEDNAA LAY IDKFGD YKSAINSIFI SEFSDKLQLM HPHQLLTYAF ALLAWPRALA RLLPLTSIPK ADEEKTFKAT HSQFLERLIR DFDN DPTRL SLIHALSLGR PALVEDLRLR LWPYTVVPGT AFNVVKAKAL LQRLNATPEY SPDGPYYEFQ TPAAPVPSAA PTPAP QRVA LKSDSIFAID CEFVRHSMPL RGHINEVNRK QHLSWCKLAP ESK

+
Macromolecule #3: ND2B

MacromoleculeName: ND2B / type: protein_or_peptide / ID: 3 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 15.756794 KDa
SequenceString: MNNNLQIENY TNKNKIVISP ISYIGNNHPY KMYTIINLCI SSSLLITNYT IAKTSIFLYL IYIFNNNIYF IIIMLFFVLY PIIFIVLIH PFIIISVNNH LINKANNKGI IINNFI(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) ...String:
MNNNLQIENY TNKNKIVISP ISYIGNNHPY KMYTIINLCI SSSLLITNYT IAKTSIFLYL IYIFNNNIYF IIIMLFFVLY PIIFIVLIH PFIIISVNNH LINKANNKGI IINNFI(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)

+
Macromolecule #4: ND4L

MacromoleculeName: ND4L / type: protein_or_peptide / ID: 4 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 19.673094 KDa
SequenceString:
MLKAIQPMSL RSRVVSRALS SGYKQFGGLT FKEVQNNEVK QNPTTFMQRP LAQIASNGLF VAWPGQFETV FDLLTSQIGP YCVIGLYLG ARGCFKPEMA WTDRLIHVEA STFLLYGVFF ITFASTPLLY WAWFFMLFSN SLKTLMFVHL SNPWYLVLDQ P MQVKFSLK RLK

+
Macromolecule #5: NDUFA1

MacromoleculeName: NDUFA1 / type: protein_or_peptide / ID: 5 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 15.659606 KDa
SequenceString:
MPGGGGWSNM VPIIILNGVV WAALGRASLA CSPPEFHKRT KNDTEFNKYL HLRFNKAVQN PESVAGQAVK AGCAPEFRPF DSPANPLVV VYGWKDEIQP RPNPGSLAQS FDDRGLSWYQ SHFSNRVVDD PKHNSLPFPG YY

+
Macromolecule #6: NDUFA2

MacromoleculeName: NDUFA2 / type: protein_or_peptide / ID: 6 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 21.331168 KDa
SequenceString: MAQVWRSRLS CHFRKLRVRY PAAKLPEAAA INWATYLDVP SPANLPAADL NKALEAMRRP NPALASSRGV REFVQRVVPE LEAENPFCP LIVDKFDPEV ASQFPSESTD PTLHAHFLDG TQVNVPLANK SAAEIEDILA DLVKLAGLLQ PQAPLEGDNL P VEDTIYAA ...String:
MAQVWRSRLS CHFRKLRVRY PAAKLPEAAA INWATYLDVP SPANLPAADL NKALEAMRRP NPALASSRGV REFVQRVVPE LEAENPFCP LIVDKFDPEV ASQFPSESTD PTLHAHFLDG TQVNVPLANK SAAEIEDILA DLVKLAGLLQ PQAPLEGDNL P VEDTIYAA ASRPRFPNYS RHAKQARLGD ESTEM

+
Macromolecule #7: NDUFA3

MacromoleculeName: NDUFA3 / type: protein_or_peptide / ID: 7 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 14.950273 KDa
SequenceString:
MDRYEFQKIR RQPPTLHWEA GNRFENIQRL RWENAALLKD PKLTWFRREM LMRPAFFHCT LFAGAVAVGY PFVAYFYEKV FPDRQDFRS TMTLLRAVGG LEEQEYYIME RAKAIERAKA RAAVQG

+
Macromolecule #8: NDUFA5

MacromoleculeName: NDUFA5 / type: protein_or_peptide / ID: 8 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 20.961854 KDa
SequenceString:
MLRAGLRCAS AAAVIGRRGY ATKVKDFTGL AGYPVEPKWR GKLLALYAET LEAVQGIPAD HPYRRSVENL TRHYARVVEE AEDYEVVET TVGLGQVEQL IRMATNELQL VRDFTVWRTW EIDERVLDKM DVDLRTSIGG HYTKRAYEVL DEVEDERRLL E KLQQEVDL EKARVAAKAA EGPKTL

+
Macromolecule #9: NDUFA6

MacromoleculeName: NDUFA6 / type: protein_or_peptide / ID: 9 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 48.78698 KDa
SequenceString: MPQMRVATKG VRPFSVRAAG GQYVLPDHGR YGQVVRPARL EEFELNPHQN PSRDRDWSVE IRGFYRDLLK SIPTMKQRFR LVIPNDVVR QNIRKRFEQG PKLTDPAALR HRALMVSADL EEYFREDFLD SQVQGKYNNM DPRTLLNQEI AAAASETQTA H RFFNEGTN ...String:
MPQMRVATKG VRPFSVRAAG GQYVLPDHGR YGQVVRPARL EEFELNPHQN PSRDRDWSVE IRGFYRDLLK SIPTMKQRFR LVIPNDVVR QNIRKRFEQG PKLTDPAALR HRALMVSADL EEYFREDFLD SQVQGKYNNM DPRTLLNQEI AAAASETQTA H RFFNEGTN VLLETGIGGE DVTENRVYIT REQAYRKGLA SLRGDAAVRH LLPAVDPANQ TTLQALAAEN DLQALVDLLG HL PAAKTAE AYVQRCEAFH KEAGLRHQKA SGGAVLAAWE KFKDEEVNST VLLHPAYKAL IADPSRNPLL RGAADWVRLV EAG GLSTTE PDSAADKLLK VAQHLYYSDQ LPEGFAQDLG VSYLADLKGV DRRLDLLLDE EIAYRQELLL KIYAHTVESI KATA SNPTD PAAVKKHLDA HDWSAFVVPT EGVKSSYEAL AL

+
Macromolecule #10: NDUFA7

MacromoleculeName: NDUFA7 / type: protein_or_peptide / ID: 10 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 16.358675 KDa
SequenceString:
MTTLKLNLKE RWLAMVHKRI QQWWQVGGDE RWVHTDPANY WWGAPAGLAS AREERQFFPS YYQRDLRRIK RKSFIMNRPM MKTNALALA DGQLPPRPHL NLADPSPFWW QSHPKDRGDR TMIYQSRSED AIEHYPR

+
Macromolecule #11: NDUFA8

MacromoleculeName: NDUFA8 / type: protein_or_peptide / ID: 11 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 25.916332 KDa
SequenceString: MTAPWNSSYT AKDWKKFPEI ESHAALQEKL DREVSSKDVV NVEKVVDDIL SHPHRKHFGT LNIPNEQTKK EHEGIFGMGI PENVLFSFG HWYRMSQPLE KAREEYLVCK HNAPKRAAPT ECLEEAKNMF NLYLHMSEIP FRTCPKQTAD YTYCVETQGH R KPGMDYGA ...String:
MTAPWNSSYT AKDWKKFPEI ESHAALQEKL DREVSSKDVV NVEKVVDDIL SHPHRKHFGT LNIPNEQTKK EHEGIFGMGI PENVLFSFG HWYRMSQPLE KAREEYLVCK HNAPKRAAPT ECLEEAKNMF NLYLHMSEIP FRTCPKQTAD YTYCVETQGH R KPGMDYGA RSFTSFVRYC LPEQEAFEEC LGKTYGCKFP PAPAHGQFYQ RSARFTNLPW DNIYA

+
Macromolecule #12: NDUFA9

MacromoleculeName: NDUFA9 / type: protein_or_peptide / ID: 12 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 54.983121 KDa
SequenceString: MARPPAEVTM LIKNAGDLLT KVKLENPPTR LLLDPKTIKL ATQDPTVKGK VKDLMLKGVK VEPSTAARVE HTFIPAPKQT ENQYSKPLL GYRLRELRTK VLSNEVYSTP RPRPLRGVVA TVFGGNGFLG NQVVAQLAQY GATVICPTRI NNEEHPVVMN T RDFRQIKS ...String:
MARPPAEVTM LIKNAGDLLT KVKLENPPTR LLLDPKTIKL ATQDPTVKGK VKDLMLKGVK VEPSTAARVE HTFIPAPKQT ENQYSKPLL GYRLRELRTK VLSNEVYSTP RPRPLRGVVA TVFGGNGFLG NQVVAQLAQY GATVICPTRI NNEEHPVVMN T RDFRQIKS LGDQGQVFPV VYNPTVFDEV AQCVERSQVV FNCIGGFYPA MNQSQSFGPE ALFANLPRNI ARACAMKGVQ RL VHTSHIN ADVSSPIPFF KYKALGEEAV LDEFPNGIII RPADIFGDRD NFTTLMVNLL KGSNWPIMST NTYLLEGNEY VEC QPVWVV DVARAMVRAA MREYTFGQTY QLPGPDRYKL IEVMRYIEAI TQLQPSHVRV YSPLEAQLRF DRPGGENHRS WIDL HLREN VVPKPGVKTW QDLEIDNSIL TKMENITGDW MSKAPYRDMP TGFDEELTDL SLPRVWGDYD KKLIAFPAVS AVAAV LYAL AILFP

+
Macromolecule #13: NDUFAB1-alpha

MacromoleculeName: NDUFAB1-alpha / type: protein_or_peptide / ID: 13 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 14.936051 KDa
SequenceString:
MLARFGRVLS VAYRTYPVGK SLVRATPFIE AQKRWGGGHG HGPVTPLDSA IHFLDREDVT KRVLKIVAAF DKVTKEVKAD SHFVNDLGL DSLDVVEVVM SLEQEFNVDM SNQDAEKIHT VKDAIDYFCA HPASM

+
Macromolecule #14: NDUFAB1-beta

MacromoleculeName: NDUFAB1-beta / type: protein_or_peptide / ID: 14 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 14.899051 KDa
SequenceString:
MLARFGRVLS VAYRTYPVGK SLVRATPFIE AQKRWGGGHG HGPVTPLDSA IHFLDREDVT KRVLKIVAAF DKVTKEVKAD SHFVNDLGL DSLDVVEVVM ALEWEFQVEM HSSEAEMIAS VADAIDYFCL HPAAH

+
Macromolecule #15: NDUFA12

MacromoleculeName: NDUFA12 / type: protein_or_peptide / ID: 15 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 33.338133 KDa
SequenceString: MIRTLLLRHS APAVITGRPQ WWTQAIAVPP TQAEMELFQP KEVVHTKPYK PHPWFKDFGQ GRRHIVGPPE RGEFWRFRKF YAVMREKTK ELGVRGALRF LVRKLRTQRE AWYEKGYEED ILVGEDEMGN KYWQSSYTTA VQSRWVEYGT GSTFTKDASV V APEWYQWL ...String:
MIRTLLLRHS APAVITGRPQ WWTQAIAVPP TQAEMELFQP KEVVHTKPYK PHPWFKDFGQ GRRHIVGPPE RGEFWRFRKF YAVMREKTK ELGVRGALRF LVRKLRTQRE AWYEKGYEED ILVGEDEMGN KYWQSSYTTA VQSRWVEYGT GSTFTKDASV V APEWYQWL HGAPDPEVQE LRPRHPAALT KGLTGDYWYR MKHSESQYAF GRKYWPRGNP HPKNTKYDDF LLRKRRLSKR RG FMEFDPF VLPAERLRKR AKWAPNPVSD RRHSAYSKNL PLGA

+
Macromolecule #16: NDUFA13

MacromoleculeName: NDUFA13 / type: protein_or_peptide / ID: 16 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 22.683824 KDa
SequenceString: MAEKAPEVHH PQDKLPEWFD PNSQQFTRNW RQAMPPKGGY PAVRHRYLSP GKGVSMRTAW AIIGSLTLFG LYQRRVDRAF ILDLGDDFH ARNCAAVPYM EAENQLKDLI SLHYEKEYRN FVAPGLKLDP SQFFNHPIPG AVGEYIRKTK PQRSTKNRVA W MNLELCTE ...String:
MAEKAPEVHH PQDKLPEWFD PNSQQFTRNW RQAMPPKGGY PAVRHRYLSP GKGVSMRTAW AIIGSLTLFG LYQRRVDRAF ILDLGDDFH ARNCAAVPYM EAENQLKDLI SLHYEKEYRN FVAPGLKLDP SQFFNHPIPG AVGEYIRKTK PQRSTKNRVA W MNLELCTE PISQLSGAPQ SGPDKYERML GFTVYEGPAF

+
Macromolecule #17: NDUFA11

MacromoleculeName: NDUFA11 / type: protein_or_peptide / ID: 17 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 32.617457 KDa
SequenceString: MFQPVWQPIL MVGSPDIILH SAERRALAWD HPNRFSALRN ALYQARLLEQ PRPENRIALL GQDLLEDTIY TTVGAYLFAG VSCIQRLGG HVPFTPSFTG QNIWTMPKWA SRLLHQVRMM RYFSAYWAVG MTYFTTYNIL TGFMGFPVNE YHNYQPQASV L SVIPTALI ...String:
MFQPVWQPIL MVGSPDIILH SAERRALAWD HPNRFSALRN ALYQARLLEQ PRPENRIALL GQDLLEDTIY TTVGAYLFAG VSCIQRLGG HVPFTPSFTG QNIWTMPKWA SRLLHQVRMM RYFSAYWAVG MTYFTTYNIL TGFMGFPVNE YHNYQPQASV L SVIPTALI YAALHPNRRP ERLWVGKATP FVGRFFLSGI VGAALAVFAA RRFAHATVSE LYHPSGSDSY FETLRNSAPS AD LVADMPY IPFYKEARCS PGLPVKSPYY DPEYVAKAKE EVKRKLDSLY

+
Macromolecule #18: NDUFB2

MacromoleculeName: NDUFB2 / type: protein_or_peptide / ID: 18 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 17.202416 KDa
SequenceString:
RSSDLVRRGA LIASLVRNRT IRPKPLQVRT GSGGHHSHSV DPNDPFDGVE NELFLPPQAY YYFSRILFVT TLIVWLKTYR DKAIDQFSF KKWVDSLPEM TIKEEEIYLD EWEDWEAPQH DVARLFPRYT KKFRKADDWN FGATVW

+
Macromolecule #19: NDUFB3

MacromoleculeName: NDUFB3 / type: protein_or_peptide / ID: 19 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 6.831087 KDa
SequenceString:
MVFWNHRRYQ FHPFINAWGK NMRHAFFPNL FWSR(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)

+
Macromolecule #20: NDUFB4

MacromoleculeName: NDUFB4 / type: protein_or_peptide / ID: 20 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 19.511402 KDa
SequenceString:
MAERTFRSLG RLPAPSAPLP HDKIAWPEKI RFLPEGSIMM PDGYSLDPNQ HFEDPYHWSV LRRAWEPKQD VFVGKDSHGN VVKQYNSPQ VRHLHPGFKL FYLYRKGAAR RFQVNAQNIA YAAIFAGTCL ALCEFGLRVQ NWAGGVNTLE KLQSTERKVK M NGKVIVAP DSF

+
Macromolecule #21: NDUFB5

MacromoleculeName: NDUFB5 / type: protein_or_peptide / ID: 21 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 15.815024 KDa
SequenceString:
FWQAEHKVYP PSKIHPGVHK GYIRTGVVHN LMRLLA(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)WAPVTALA SFATWR YRA EVAEWLDNLS NVDYPKWLAE REIAIRRVET EIFWRIEGHA QQRSQVASGQ GRAMLNKAAK ASYEESEASR LHGAGVS DL LK

+
Macromolecule #22: NDUFB6

MacromoleculeName: NDUFB6 / type: protein_or_peptide / ID: 22 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 10.926597 KDa
SequenceString:
DIDLGPHPYR PDFAGHAPNP KHWRRNTFFL SCGILLIYYQ CCKLEFYHGR FLEPPIRPFP LQGYFRNVYL DDPNYDDKKK LMKEDFAKL KA

+
Macromolecule #23: NDUFB7

MacromoleculeName: NDUFB7 / type: protein_or_peptide / ID: 23 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 12.247089 KDa
SequenceString:
EVFDNELVSY EGVDWEKIPN RFKRRRMPLS DEVMDEWKIP YRERDYCVHK LLELRKCVQK TFYRGECDHH RHEYHMCQHL ELRRRKAIK DLREELGR

+
Macromolecule #24: NDUFB8

MacromoleculeName: NDUFB8 / type: protein_or_peptide / ID: 24 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 20.488459 KDa
SequenceString:
MLATRLRRPA VGLARTTIRM QARTRFMQME YWEVPMEADH PEYRPVVHDQ FLPFVGAPGV HWNPTPYPVG YDLWWNSFEA LAMDIHDMG HQESIGESLE KYLLGAGLCF AIFNFLILFD CHFWFSEVNA GHPLYPKQFH YLLRGGDPTD EIWLAQQQRE K ELMEHGKA LVKGEAKA

+
Macromolecule #25: NDUFB9

MacromoleculeName: NDUFB9 / type: protein_or_peptide / ID: 25 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 18.347 KDa
SequenceString:
MKRSLLKLKD LKKVKVTQPQ SSIVLKPVPI GEPIIWSRVQ HLYWRALHVI EDFPWMGPSQ TSEQFDIMLS VKEEIQKNAN AAGALKDRL LEDFEAHIKR RDWMQRRVHY FANGGPGYQT FASERHTLEQ QGVWKAGTPI PFPKSDYNDD GPVEKGPYY

+
Macromolecule #26: NDUFB10

MacromoleculeName: NDUFB10 / type: protein_or_peptide / ID: 26 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 17.471033 KDa
SequenceString:
MGQHFGKLGW DADDVYKVTT FEKHNYTVEE PRTPAFKAPR RPFPICDRPP MPDQEGLYET HADLYEMKRW VMWEWSVYCK ELSLVREEL KWCVAREGSN AHRECHDLAR QYTDMTRKLK MEERFSWLNH FKKPLVKDVL FDLKQ

+
Macromolecule #27: NDUFB11

MacromoleculeName: NDUFB11 / type: protein_or_peptide / ID: 27 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 13.048724 KDa
SequenceString:
GGVSRPVRSK RETDFNSSDP WETPFGRIEH DDEDIPYTTT VYQPRRPTEW STDVIWHAVL LMFFVWFTTL QGILVPQNKE NDMAWEEAL RRRRLFREKQ V(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)

+
Macromolecule #28: NDUFC2

MacromoleculeName: NDUFC2 / type: protein_or_peptide / ID: 28 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 22.010127 KDa
SequenceString:
MDRSSVTPRQ VFLEPVELPF AKKDASLEIF TESQLKSLLE PADASLFKWK NLAKWKKEVR TLLPQEFQSW DPISNQETIV DLNPYLVGG IFGGFNAMAH NYLSCTVWWK VPWRFPMWMA AWAGVSAYLF EFRREVEYEN RKSRLLVNNY YNRVRTVIVE R EKRKNGPD HQFKDLPWMD REEQRSG

+
Macromolecule #29: NDUEG1

MacromoleculeName: NDUEG1 / type: protein_or_peptide / ID: 29 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 53.351969 KDa
SequenceString: MRRVGVYALR CARGHASSAL AAAPASETLT VGSLYSKKLR EYPHKVLWRR KTGFENSSWN QCRRSHEALA TNFSEIEVGD RALFITDCD SLMVNVALAI QKRGAQVCIV PAQGLTSNKL ETYIEQLRPK VIFLGKDKVS VPDPLGGDEA PQKMTLDLYS M IWKIFPIS ...String:
MRRVGVYALR CARGHASSAL AAAPASETLT VGSLYSKKLR EYPHKVLWRR KTGFENSSWN QCRRSHEALA TNFSEIEVGD RALFITDCD SLMVNVALAI QKRGAQVCIV PAQGLTSNKL ETYIEQLRPK VIFLGKDKVS VPDPLGGDEA PQKMTLDLYS M IWKIFPIS NVVEGLPLQS KRYPFVKSVV LCSQVDAINQ HDMITNIKYF ETPRDQDYYE SPLVHIAMHI APDFPALSVV DS AGKWTTH SHTTLLNAGR LFAAKYFGKA EHVLLLPGSE STPGGILTLY AALHAHAVLC YGEDQLVTKG DCKRVTRAVH QHE ATAVVG TKAQWDFLLK YGDAATKKED ATKEWFKSLK WAAVFLNDVE DAGDLASKIR SSFGIDRVEC IRGSPETLNL TSDG SGKLF DSLSVVIKDK DGVATRGDAE GFVWIKGPHV SAQYWNHIGL MSAPKDPNGY VKLPYVGKKK PDGGFTITTV QPVRE LVL

+
Macromolecule #30: NDUEG2

MacromoleculeName: NDUEG2 / type: protein_or_peptide / ID: 30 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 50.515348 KDa
SequenceString: MVIGTFFKTG FEKGLPLHEQ VVRHLLPLVP KARKGFWPYY FAVNERVVLP RRAGAALNSR LRIPGKNRRE CLPTSASSPL ELAQLRKAT DKPVEDVKPQ VFVSTSSPSD AVPLHNESVH SKWLEALDEV NKTASTFSDA FEIQNESLSK EIFHRLAVPA S LKAGNIFA ...String:
MVIGTFFKTG FEKGLPLHEQ VVRHLLPLVP KARKGFWPYY FAVNERVVLP RRAGAALNSR LRIPGKNRRE CLPTSASSPL ELAQLRKAT DKPVEDVKPQ VFVSTSSPSD AVPLHNESVH SKWLEALDEV NKTASTFSDA FEIQNESLSK EIFHRLAVPA S LKAGNIFA HDGAFGSNSA DDIKFTAVTH DPTAALFLRH MVNPVPQVDP VDFPNLFSVF HIHDYEFTDP RIVEEFDGVK KE QLGITSP RFVLYDLAER NVYVSGSSQD LRDAIVCLGG LVAFHLYGSL TLACNSFIDK DGKLTLVFGS EANLNSPQLF GAH HSLWTP NGVSRAWNGV TVEGAKAQFA SDLVEVTAKG PRLTAPLPLQ LGGTARPRGA NLLAGAAAGT PEPPLAVDPK LPWR PNVVS AAGAKFVFVG KEEAKLSVDD AAALFADSHA AYPLGFSTKK KLAAKFKELA ATAPGASFVT TP

+
Macromolecule #31: NDUEG3

MacromoleculeName: NDUEG3 / type: protein_or_peptide / ID: 31 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 46.409844 KDa
SequenceString: MSRNVLTKGW RFHAHAGTFQ SALRFEEFQL KKSVGDVVLR LQCAPVTGFD LDQVRGLQGK VPLPAVGGLS GVGVVTEGSG IFKEGDRAV LLGANGAWSQ YAVSSANHLL SVPATIPVEY ASLLASGPFA AYRILKAAHL KAGDLVLVNG AHTAIGLAAL Q IAKAWGID ...String:
MSRNVLTKGW RFHAHAGTFQ SALRFEEFQL KKSVGDVVLR LQCAPVTGFD LDQVRGLQGK VPLPAVGGLS GVGVVTEGSG IFKEGDRAV LLGANGAWSQ YAVSSANHLL SVPATIPVEY ASLLASGPFA AYRILKAAHL KAGDLVLVNG AHTAIGLAAL Q IAKAWGID AVGVAHGAPA LQVEKLKQMG LNVVSSFALD PKQVFGTSQP KFAISLVGGN AAAYVTHLIG SDGHIITCPL AS DEPHILP NVDLVNKNLT IQTFSPWKSL LSATATENEQ MVSELCDLIA AHKLKANAVV RHEFGNLLDA IREAEHGTHN AVI LHEGTE KTWDNKNHDI YMEIDDKLQA NWDAAAAAQD PYLKTGRDQP WQVLAEAEEV ALPDELRVKL AAVTTEAELL AVLD TLTLK ERHLLGLPAT QAITVSAEEL KKMVSEFAS

+
Macromolecule #32: NDUEG4

MacromoleculeName: NDUEG4 / type: protein_or_peptide / ID: 32 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 41.313383 KDa
SequenceString: MQSLKRAGTL SRPFLRCFYD AGAPQIFRSN VPGRPLPWRQ ERQVPPNPSQ SKWQWEPEHI PTAEEYEAFP EVITLYGGDG LLRSSVIQE LVQSPRVSTI RVGTPWPDEF ASKLPGEWQS KVVAEFVDIL DRHSVLAAAE GSQALVNMMD IPYECELTYY Q AHVGSAQM ...String:
MQSLKRAGTL SRPFLRCFYD AGAPQIFRSN VPGRPLPWRQ ERQVPPNPSQ SKWQWEPEHI PTAEEYEAFP EVITLYGGDG LLRSSVIQE LVQSPRVSTI RVGTPWPDEF ASKLPGEWQS KVVAEFVDIL DRHSVLAAAE GSQALVNMMD IPYECELTYY Q AHVGSAQM ISHAANTCMC SRVIHVSSLA SRVDSWSRYS ESKFRGEDMS LACFPWTTIL RFGPLVGKNS PALKQFASYM KY APIYPCV AKDTKIQPTF VGDAAKAILA ALGNPSTRQL QFDLGGPEVF KHADFIKEVM RLTKASRPVV PVPGVIGDSI VAL LQWLPD PLVTRDMVYL IRSHHIANHD SMRTWKDLLP EHKLKTMAEA LQ

+
Macromolecule #33: NDUEG5

MacromoleculeName: NDUEG5 / type: protein_or_peptide / ID: 33 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 29.182729 KDa
SequenceString: MALAKGWRFS AHGGTWKAVL KLEDFPLTKT AGAAVLKVQA APVTPRDLDR IRGLYGALPL PAVAGTSGVG IVTQAGGAFK EGDRAVLAA ANPAGSYATL AAVDPAHLIK VPAALPVDVA ATLAVGPFAA YQILKLSGLK SGDSLALDGE ATLLGKSVAL L AKSRGITV ...String:
MALAKGWRFS AHGGTWKAVL KLEDFPLTKT AGAAVLKVQA APVTPRDLDR IRGLYGALPL PAVAGTSGVG IVTQAGGAFK EGDRAVLAA ANPAGSYATL AAVDPAHLIK VPAALPVDVA ATLAVGPFAA YQILKLSGLK SGDSLALDGE ATLLGKSVAL L AKSRGITV VSGAAAGKDI KFALSLQGGR SASSLLGALG HGGQLLLHVA PSDEATVLDG ALVADKSVTI RSFAPAAVSA KE AEAMVEE VVELVKGNAL GLKVVRHDLA KLLEAVEEVT AGPSDTVHIL TLS

+
Macromolecule #34: NDUEG6

MacromoleculeName: NDUEG6 / type: protein_or_peptide / ID: 34 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 43.669457 KDa
SequenceString: MWRTSGCALR SRASFTTAVT AHASGVKAID PFKILSLPDS ATRDDLRNQF FELAKSNHPD VGGDKAKFQA IQDAYEDAIR IADQKHPVA PWDGISPMTY AQAWQGKDYW RKLWEEHWAA RLAHMYKHNA ELTTLEANKK WREAQYMQVK DWMVLAKDVL D PKTKAEWQ ...String:
MWRTSGCALR SRASFTTAVT AHASGVKAID PFKILSLPDS ATRDDLRNQF FELAKSNHPD VGGDKAKFQA IQDAYEDAIR IADQKHPVA PWDGISPMTY AQAWQGKDYW RKLWEEHWAA RLAHMYKHNA ELTTLEANKK WREAQYMQVK DWMVLAKDVL D PKTKAEWQ AGCELARDML LWTQANKKNY RRYFLSNQNV AVNMRQVYDE HEYWRQYENV QWAQWDAFFA RASAWALEHE EQ IRSVNST EGPLAAKFDY LFHGRLQYSS MSLEERLSRR AQEEKAYTRQ YWIAELMKAM RFSFRWVERF SRAFFPVLIL VVI AGYITD FQLIIRWLNI TRSETGALEV HNRKMDMVDW LLAGTPTPQN IEGTI

+
Macromolecule #35: NDUEG8

MacromoleculeName: NDUEG8 / type: protein_or_peptide / ID: 35 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 23.994727 KDa
SequenceString: MTTHRPPLVT DRMFPWTWNS RYYMMTPLAT YGREDIFANP HLPADKKLHA AAVEGGEFMK DAYAPPHKAV SLVRRVGRKA MVGAGLYFH LFLMDKFVSK GLLDRNTSPY FYMTLYEKAI YCLLPNKNKP NEEDLLKLFR EARLESNYKS VSMWTYRLRS E RVPKSYFD ...String:
MTTHRPPLVT DRMFPWTWNS RYYMMTPLAT YGREDIFANP HLPADKKLHA AAVEGGEFMK DAYAPPHKAV SLVRRVGRKA MVGAGLYFH LFLMDKFVSK GLLDRNTSPY FYMTLYEKAI YCLLPNKNKP NEEDLLKLFR EARLESNYKS VSMWTYRLRS E RVPKSYFD KPPVSYDADR RTSGFVEWAF WMVGLESFGK SVVPEAW

+
Macromolecule #36: NDUEG10

MacromoleculeName: NDUEG10 / type: protein_or_peptide / ID: 36 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 14.140555 KDa
SequenceString: MSKQNHGLHN RLIPIFVKEN AFNGFPLVNK GKWGSWLWFR NTQLKNLYHP LGAVLKWPRS FLMLNGTETA FWMVFFWAAA NTWLYSRQR KEFIKDCDYG (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK) ...String:
MSKQNHGLHN RLIPIFVKEN AFNGFPLVNK GKWGSWLWFR NTQLKNLYHP LGAVLKWPRS FLMLNGTETA FWMVFFWAAA NTWLYSRQR KEFIKDCDYG (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)

+
Macromolecule #37: NDUEG11

MacromoleculeName: NDUEG11 / type: protein_or_peptide / ID: 37 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 11.472202 KDa
SequenceString: (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)SL QCHDTRNRRD KCMVQHGFCA QQI EDHFEC LEQYYQKEKV ...String:
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)SL QCHDTRNRRD KCMVQHGFCA QQI EDHFEC LEQYYQKEKV DQLRREFRSQ SFQMVKQMKL EDLGHFDRYG NLR

+
Macromolecule #38: NDUEG12

MacromoleculeName: NDUEG12 / type: protein_or_peptide / ID: 38 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 11.323098 KDa
SequenceString:
MHRIATRVAM QQRFYGVARP DVQNRVIQTV QPFVDICCRP RTEVKPTSHF VLDLNLPAVH LKQVVLALEG EFAAPVPDAQ FKNIVSVAD AVEYFAGHPQ AK

+
Macromolecule #39: NDUEG13

MacromoleculeName: NDUEG13 / type: protein_or_peptide / ID: 39 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 17.731408 KDa
SequenceString:
MAHDKPHNEP PKRLLSKQEK TDMAVRENIE KPSWIKENGF QRWCYEMVRG VGRHPWPRYF ELTDFFGDKR HGDAIPRSWA AVKKLERGQ VIGPAVCVTL TLWVFVAGTI SKRNNTVWCD SIQEKYGFKQ PYSREFRTQH DGVLKPKLPA IY

+
Macromolecule #40: NDUFX

MacromoleculeName: NDUFX / type: protein_or_peptide / ID: 40 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 37.196953 KDa
SequenceString: MTTIHAYTAT QKTVDGPSKK DWRGGRAAAI TMVFRPLFRS FVNPFSLARL MAFRPTSVLA LRTCQLRLGG GHGHGHGHGH GHGGHGGKP NKFENHIYRD ASGQPWFDLH KWELGRKPGK EDLEHPGRHE SFSQTKRLVS LTFIDKDGNP HNIKCEPGMN M ADAALQAG ...String:
MTTIHAYTAT QKTVDGPSKK DWRGGRAAAI TMVFRPLFRS FVNPFSLARL MAFRPTSVLA LRTCQLRLGG GHGHGHGHGH GHGGHGGKP NKFENHIYRD ASGQPWFDLH KWELGRKPGK EDLEHPGRHE SFSQTKRLVS LTFIDKDGNP HNIKCEPGMN M ADAALQAG VSLDWLDGEG NQGFSAWSHM VISSPQFEML VPPDHREDKY LWDLEQWGTS HRNSRFVKFL FVQPWMEGMV VT HPFFADV VTPNFTDPFT GKIEDKDQAV APTYFVSKVV DPEKPDYKFP NPFELLWAGI DTYEQLWDYT RQSWLKRLEA RRQ KQQQA

+
Macromolecule #41: NDUCA1

MacromoleculeName: NDUCA1 / type: protein_or_peptide / ID: 41 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 48.726906 KDa
SequenceString: MAKLTWLKNL LNPYSRVPPS TFLRFFPRLL NKFGSAERDI NAEFPGTVHK HIKTYQERFM EQGAGDRIAT KWNPKPWEKA YMGQPDHPM TKAEQAKKED FMVGIHWDRS AGGRWTPNDK FPLFDYEFPI HPGRIILRWL YKQGKEPVNM QRSILVTDDF A TPSVYPFG ...String:
MAKLTWLKNL LNPYSRVPPS TFLRFFPRLL NKFGSAERDI NAEFPGTVHK HIKTYQERFM EQGAGDRIAT KWNPKPWEKA YMGQPDHPM TKAEQAKKED FMVGIHWDRS AGGRWTPNDK FPLFDYEFPI HPGRIILRWL YKQGKEPVNM QRSILVTDDF A TPSVYPFG WHAPSAILIG DACISNDAAV FDHCVLRADR AAIWVGPKSH VLEGCTLTTA PPTPDRPALG SVLIGENTVV GA GSSLNAC WIGDHCIIGS GCTIGFGARI DDGAVVGAGS VVEDDQYIPA GEVWVGRPAR YLRKTGDVDT FTAVAENDTL RSL HLAYSE YETTHGNVWA ESDKVCDNLE EEVAHRLQAH DVARAMVSKN FDAKLLKLPK SLVADLMDIV SDDDHPNPKP TVSA QARQH FSSQWDFNRK QEQRPVFTGN YNSPTMSRDM A

+
Macromolecule #42: NDUCA2

MacromoleculeName: NDUCA2 / type: protein_or_peptide / ID: 42 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 28.857973 KDa
SequenceString: MPLPQKSTLV RLGAAIRECG QALDRWGSFL QGRYGHLEKL QRTRRINGFH NFFPEVKGVR FIAPSASVIG QVTVSPGSSI WYNSVVRGD RGKVTIGEDT HILERVVIRS GILSVRDVKI GKDVIIEPGA IISPCQIEDG AYIGANAVLM EGCKIGKGVV V GPGAVVTE ...String:
MPLPQKSTLV RLGAAIRECG QALDRWGSFL QGRYGHLEKL QRTRRINGFH NFFPEVKGVR FIAPSASVIG QVTVSPGSSI WYNSVVRGD RGKVTIGEDT HILERVVIRS GILSVRDVKI GKDVIIEPGA IISPCQIEDG AYIGANAVLM EGCKIGKGVV V GPGAVVTE FAELTQPGVY QGVPAKSATA LTTEAAEAIT TRRAEFAKLA EEHEEMNTKL IEKQTEERVI LKDILENQLN EG NEFTMRS HHVARAPNVS PGNIAAGSAA

+
Macromolecule #43: NDUCA3

MacromoleculeName: NDUCA3 / type: protein_or_peptide / ID: 43 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 28.0169 KDa
SequenceString: (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)GAA IRECGQALDR WGSFLQGRYG HLEKLQRTRR INGFHNFFPE VK GVRFIAP SASVIGQVTV SPGSSIWYNS VVRGDRGKVT IGEDTHILER VVIRSGILSV RDVKIGKDVI IEPGAIISPC QIE DGAYIG ...String:
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)GAA IRECGQALDR WGSFLQGRYG HLEKLQRTRR INGFHNFFPE VK GVRFIAP SASVIGQVTV SPGSSIWYNS VVRGDRGKVT IGEDTHILER VVIRSGILSV RDVKIGKDVI IEPGAIISPC QIE DGAYIG ANAVLMEGCK IGKGVVVGPG AVVTEFAELT QPGVYQGVPA KSATALTTEA AEAITTRRAE FAKLAEEHEE MNTK LIEKQ TEERVILKDI LEDQLNEGNE FTMRSHHVAR APNVSPGNIA AGSA

+
Macromolecule #44: ND1

MacromoleculeName: ND1 / type: protein_or_peptide / ID: 44 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 79.682836 KDa
SequenceString: MLNSNIYIII YGGIIMYSIM IIIQMFLYNF SNKIYIEVEI NKYILSKNNI DIYWIICNCT IIIIITTLNH IINKIGIYNM IEYNICYWL IGTGLGLYIS PFIVFGYKFF VYIMDLNNYS LNIYHNNNKM NDIQQIYNGT NYNDTMIFFI KDINNIFTIY R SINFFMNW ...String:
MLNSNIYIII YGGIIMYSIM IIIQMFLYNF SNKIYIEVEI NKYILSKNNI DIYWIICNCT IIIIITTLNH IINKIGIYNM IEYNICYWL IGTGLGLYIS PFIVFGYKFF VYIMDLNNYS LNIYHNNNKM NDIQQIYNGT NYNDTMIFFI KDINNIFTIY R SINFFMNW LYQMIYYGVR MWLVFVLHSF SLGSFGELIT VITDNNLIFN VFYIGLLGLG VILYLIVIFY LGIQIYVYIS FS LSFLHST ILLFLVNYIP HYNNKSIFNT FTNKSIYLIP VSLVDLININ IIFYILLLYT LLLFFIPLFL ASINYTYHYI YKY YNYNYN FINNNTNTNN NNKFINISYN FFIILIILNI INISSIYNIL QILLIMLIVL SLSSLLTVLE RKGLASSQRR IGPS YNGWF GLVQIVQDGI KLIYKDYNRY NNINNKYIMI SCILNFIYSY LLFIFIYIDL ILYINISYII FMIIIILMIN HITII ICGI VINNSKWTIL SSIRLILLYF MYDIIFLLIL LYLSPINNLG INLLYNNNNL NLNNYIESQF YYINLYKYPL LLYIYI FIV LIEAGRIPVD LIESESELIS GYSIEYSGFL YALFASAEYS IILFHSILLS LLFFSYYSFN ILFIHITILF FIFVIIR ST LPRFKYTNLF NLTYYYILPF ILTYLLLL

+
Macromolecule #45: ND2A

MacromoleculeName: ND2A / type: protein_or_peptide / ID: 45 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 35.864434 KDa
SequenceString: MLYNNNLIII ILMISIIIGI SLQNILVNDI SELRWINRFN LDNFIIIYII LLYNNIILIL GIISLIISTN KNTTNNKVQL IHMIIIIIN TIYICNNNNN TIINIILMII TIDILSVLNI ILIQKGEGIW YYFLYQSLMT ILIWWVLILD LSSLLSFFYY Y KLGSGIGG ...String:
MLYNNNLIII ILMISIIIGI SLQNILVNDI SELRWINRFN LDNFIIIYII LLYNNIILIL GIISLIISTN KNTTNNKVQL IHMIIIIIN TIYICNNNNN TIINIILMII TIDILSVLNI ILIQKGEGIW YYFLYQSLMT ILIWWVLILD LSSLLSFFYY Y KLGSGIGG YYIPSLYSSI IYYNINLMIY IGTTNIILMY NPIFLFNNFN HNYFLIISNF LFILYILYIW IFNGYLFINL WL YSISFST IILANIYYLF TSIDFIYYNL FYYIYYFTIS SIIIWFIFIL SLYFINNYNN HIN

+
Macromolecule #46: ND3

MacromoleculeName: ND3 / type: protein_or_peptide / ID: 46 / Number of copies: 2 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 34.504223 KDa
SequenceString: MINNIIDIYI FNNNIINKSL INIIDIIILN IGILLILVEG SIRGIIGLII VGISINIYLI NNGYILISLL LIISIISISI IISLIKYNT MSIYKFNNNK YIQLFFILYL YIILINNNNY NNNINNIEII GYILIFESNI LLSLLILIMF MFIIILVKFN N KISINYNI ...String:
MINNIIDIYI FNNNIINKSL INIIDIIILN IGILLILVEG SIRGIIGLII VGISINIYLI NNGYILISLL LIISIISISI IISLIKYNT MSIYKFNNNK YIQLFFILYL YIILINNNNY NNNINNIEII GYILIFESNI LLSLLILIMF MFIIILVKFN N KISINYNI IYFNVINYII LNIYILFIIA LLICYIPIII RYKSKIYKWS SDIYEVGIGV NMSNSIYNSI SNYNIGNYFI YF YIYLFIF LDIIINIIIL IYFININLFT YYFTLFFLIL AISYSLLFSY NFSNNF

+
Macromolecule #47: NADH-ubiquinone oxidoreductase chain 4

MacromoleculeName: NADH-ubiquinone oxidoreductase chain 4 / type: protein_or_peptide / ID: 47 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 56.417312 KDa
SequenceString: MIYKIIILRY ISILIIMIIQ LMKMYNKEYR LISIISIISI LSIMNWPQSI KEINIYIINL IIGYEINLSY NYIGIYMSLI LDILIWISI LYERYYIKNN NTYNIIIYYI INNIFFSSND IITISLIYEF QTIPLLLIIN NSYNKINIYN KKGIGISNIL L ILYSIISG ...String:
MIYKIIILRY ISILIIMIIQ LMKMYNKEYR LISIISIISI LSIMNWPQSI KEINIYIINL IIGYEINLSY NYIGIYMSLI LDILIWISI LYERYYIKNN NTYNIIIYYI INNIFFSSND IITISLIYEF QTIPLLLIIN NSYNKINIYN KKGIGISNIL L ILYSIISG LLLYNSMYNI YLLNHTSNIS HNINILNYSY NHILINYILI NILISGSMKL SIFPFHIWLG KVHVEAPTIG SI LLAGISL KTGFYLHYLF IYLYQYIYIN YLIYFIYILF IGIIINNINI FYQIDTKRWI ALYSIIHMNL YYIIMLILLI SNN NNLYYI IFINILIYGM IGHSLISGGL FLIIGYIYDI TNNKNLYLIN NNIISSYIYF ILLLLLLANS SFPLFVLFIF ELLA FTSLS IFNILLSIFL LILSCSNLLS SLYIYYKYFY THYYSPIITF TSFDFILIIL AIPILIIIIL MGFNLLLPIH FLI

UniProtKB: NADH-ubiquinone oxidoreductase chain 4

+
Macromolecule #48: ND5

MacromoleculeName: ND5 / type: protein_or_peptide / ID: 48 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 68.375359 KDa
SequenceString: MLIISIIKWL IISIIMNLSG NIIGINGLIY IIMLILVLSP IISWYVLYNI IIINIYNNKL IYLLSYNFIN YYNYNIDLEI GISIYEMIT VILLINVSYM INIYILKYLY KDKNVIRFVC IIMLFTYNMI LLIISNDLIM LFIGWEMIGI ISLLLINYYN N RIEATKAG ...String:
MLIISIIKWL IISIIMNLSG NIIGINGLIY IIMLILVLSP IISWYVLYNI IIINIYNNKL IYLLSYNFIN YYNYNIDLEI GISIYEMIT VILLINVSYM INIYILKYLY KDKNVIRFVC IIMLFTYNMI LLIISNDLIM LFIGWEMIGI ISLLLINYYN N RIEATKAG LKAVVYNRIG DVFLLLSIIL SINMYNSNSI LLYNILISYM YYNINYININ LIIGMSFIIC AWSKSTQLGF QP WLLDAME GPTPVSALLH SATLVTAGII LLYKNRYILY YNSSLAILLL ILGGISCLLN SFSSINYLDI KRIVAYSTCT HIS LMIMIL GIDILINISE ISLLHLFYHG WSKSLIFMLC GYMISIIHSQ DLRFFGNLFQ HIPILFVIIN ISLLTILGFP GSYL SYSKD IILEFGLISI YGYNIILLFI IIILLSQGYS LGILLYLIYN YSYYNSTHNI YNFYSNKNNY IYIFAFLYLI IIIIY LPFL LYDILIYNNI SIMHHISYID PFSLIAFLGF ILSYYNYNYN HTLYIFNIHN NRLYIDKLLS SFMSIFSIHI IYYFQF ILE YGFIMHYLHI TNIIIFLIFL I

+
Macromolecule #49: NDUFS2

MacromoleculeName: NDUFS2 / type: protein_or_peptide / ID: 49 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 45.251949 KDa
SequenceString: MPARADARTM QHFTLNFGPA HPAAHGVLRL ILEMNHEYII RADPHIGFLH RGTEKLMEMK PVIQVTPYMD RLDYMSAMAN EHAFIMAVE KLCEIPVPLR GSYIRVIFLE ITRLLNHLLA VACAAADVGA LTPILWTFEE REKLMTFYEC VSGS(2MR)MH PN FFRPGGVASD ...String:
MPARADARTM QHFTLNFGPA HPAAHGVLRL ILEMNHEYII RADPHIGFLH RGTEKLMEMK PVIQVTPYMD RLDYMSAMAN EHAFIMAVE KLCEIPVPLR GSYIRVIFLE ITRLLNHLLA VACAAADVGA LTPILWTFEE REKLMTFYEC VSGS(2MR)MH PN FFRPGGVASD LPYGFLDQLY EFINQFAARL DEVEDLLTQN NIWRERLKAG YMDLDRALSY GFSGPMLRAT GVAWDLRV T APYEVYPYLD VEVPYGVNSD SYDRYLIRMQ EMRNSIRIIH QCINDIVPGD YRLHDAKFAT IPFRDCKDSM ENLIAHFKY YSEGFRIPEG FVYCGTESPK GELGVYLQSN GDSLPYRVRI RAPGFYHLAA LPALAQDTMF PDLVTVIGTL DIVFGEVDR

+
Macromolecule #50: NDUFS3

MacromoleculeName: NDUFS3 / type: protein_or_peptide / ID: 50 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 32.466703 KDa
SequenceString: MFRRVATHVV PKLSTLLRAR NSIKFVTTQE VPPVHQGREV KSTPQNKGKD EFVRYLSSVL YPMASEIMWD DVTNDVTINV YPQYIRPVA KMLRDHQQFQ YKVLVDVTCV DTMTNLKRFD VVYNFLSVVF RHRVMVRASV DDASGIDSLT PLFHSAMWAE R EAWDMFGV ...String:
MFRRVATHVV PKLSTLLRAR NSIKFVTTQE VPPVHQGREV KSTPQNKGKD EFVRYLSSVL YPMASEIMWD DVTNDVTINV YPQYIRPVA KMLRDHQQFQ YKVLVDVTCV DTMTNLKRFD VVYNFLSVVF RHRVMVRASV DDASGIDSLT PLFHSAMWAE R EAWDMFGV FFVGHPDLRR MLSDYGFEGH PLRKDFPLGG YTEVYWDAPN STIKYASPPI FREEYRDYEN IETEWDDLYH RC NTAWAYD RMVKQGMESC DADYTYDDPA AHKKPQQTQG

+
Macromolecule #51: NDUFS4

MacromoleculeName: NDUFS4 / type: protein_or_peptide / ID: 51 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 23.736867 KDa
SequenceString: AGLAARPLHT SAPRLIFPFR RPFKSEPEDE TKIPDCYVNG KPIADGQGYQ AIGLAEHFER IRRNVNIRRR VPSRFTQMVG GRRARTFSI HFERGSVERE WNQGGRLGVE PFAMMRRKMK NFPTVEDAEA FALSAGWKIN SSNPGNMRFN PRVGGNRREF K QRYEFAKD ...String:
AGLAARPLHT SAPRLIFPFR RPFKSEPEDE TKIPDCYVNG KPIADGQGYQ AIGLAEHFER IRRNVNIRRR VPSRFTQMVG GRRARTFSI HFERGSVERE WNQGGRLGVE PFAMMRRKMK NFPTVEDAEA FALSAGWKIN SSNPGNMRFN PRVGGNRREF K QRYEFAKD SYMAKDSGKG AQYPQDPHSS GTRGTSSFQA KVTKRVVQQE

+
Macromolecule #52: NDUFS5

MacromoleculeName: NDUFS5 / type: protein_or_peptide / ID: 52 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 14.244042 KDa
SequenceString:
MDRYGKKDES TWWVLHPFHE KTYTEDLGKV STVEPSVCDE YIELFKRCAA KSLDPEAQCR SYQEDLKECR LGAKQRKFLS QYEFATNSF TVNEKNDFRN RWHETFFRGS LL(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)

+
Macromolecule #53: NDUFS6

MacromoleculeName: NDUFS6 / type: protein_or_peptide / ID: 53 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 17.101748 KDa
SequenceString:
MATTSRLSKV TVNIMPASRA LGVKPHRHRK QWQMPEVSFL KDVFSDPLMT EQKITERFIK AEFGPNRIDV RRAVPPIVVP KTFKHAWCD GNWGNRSTHG HPRISIRMKA GKVSQCKYCE NKFVRDDFPA FFAKREQVAA EEKYHDED

+
Macromolecule #54: NDUFS7

MacromoleculeName: NDUFS7 / type: protein_or_peptide / ID: 54 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 22.837303 KDa
SequenceString: PQVKLLATWN PYNDPSLESV LQGDRKQTHM QRYAERQTLL GEELTPGQTH IRPGDNSVSW VSTTVSQVFK WGRSGSVWPL TFGLACCAI EMMQAYASRY DLDRYGTVPR GSPRQSDLII VAGTLTNKMA PCLRKVYDQM ATPCYVISMG SCANGGGYYH F SYAVVRGC ...String:
PQVKLLATWN PYNDPSLESV LQGDRKQTHM QRYAERQTLL GEELTPGQTH IRPGDNSVSW VSTTVSQVFK WGRSGSVWPL TFGLACCAI EMMQAYASRY DLDRYGTVPR GSPRQSDLII VAGTLTNKMA PCLRKVYDQM ATPCYVISMG SCANGGGYYH F SYAVVRGC NRVVPVDIYV PGCPPTAEAL VYGILLLQRK IKMG(UNK)(UNK)(UNK)(UNK)(UNK)

+
Macromolecule #55: NDUFS8

MacromoleculeName: NDUFS8 / type: protein_or_peptide / ID: 55 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 24.370025 KDa
SequenceString: MQHLKLARRG LPLQQLRSFH WTAPPLLRQP HPDVPKDVSG LGMGLAFMNQ FLLKEIMKAM WIVTIYTFRQ PSVTIHYPYE RNTKSTRFR GEHALLIYPD GDERCITCQL CEVTCPAQAI AIDGVEDDDG SRMASRFDLD MHKCIYCGLC QEACPVDAIV E TPHAEFCS ...String:
MQHLKLARRG LPLQQLRSFH WTAPPLLRQP HPDVPKDVSG LGMGLAFMNQ FLLKEIMKAM WIVTIYTFRQ PSVTIHYPYE RNTKSTRFR GEHALLIYPD GDERCITCQL CEVTCPAQAI AIDGVEDDDG SRMASRFDLD MHKCIYCGLC QEACPVDAIV E TPHAEFCS TEYDSLLYDK ARLLENGIRW TSAIEYMVAK ERSDFPTNSQ RFKS

+
Macromolecule #56: UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK

MacromoleculeName: UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK / type: protein_or_peptide / ID: 56 / Number of copies: 2 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 1.039273 KDa
SequenceString:
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)

+
Macromolecule #57: NDUFV1

MacromoleculeName: NDUFV1 / type: protein_or_peptide / ID: 57 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 57.940191 KDa
SequenceString: MLLRGVRCGA LAGKQRRSII QVPDKAPKTP AGFLQDKDRI FQNIYNDHGQ GLKNAQKLGD WYRTKDLLAK GPEWIIDQIK KSGLRGRGG AGFPSGLKWS FMPKKPPADG RPSYVVINAD ESEPGTCKDR EIMRMEPHKL VEGTLIAGFA MRARAAYIYV R GEFYNETL ...String:
MLLRGVRCGA LAGKQRRSII QVPDKAPKTP AGFLQDKDRI FQNIYNDHGQ GLKNAQKLGD WYRTKDLLAK GPEWIIDQIK KSGLRGRGG AGFPSGLKWS FMPKKPPADG RPSYVVINAD ESEPGTCKDR EIMRMEPHKL VEGTLIAGFA MRARAAYIYV R GEFYNETL SVEKAIKEAY DAGLLGDNAC GSGYKFDIVL CRGAGAYICG EETGLIESLE GKSGKPRLKP PFPANIGLWG CP TIVTNVE TVSVSPTILR RGPEWFASFG RKNNSGTKLF CISGHVNTPC TVEESMSIPL RELLEKHCGG VRGGWDNLLA VIP GGSSVP VLPKSICDDV LMDFDALMDE GSALGTAAVI VMDKSTDLIK ALARISMFYK NESCNQCTPC REGAGVMANI MDRI WKGNG FGPEVDMIKD IADNVELRSI CALGAAAAWP IQGLHKHFRE EMIQRIEDFT DISYNLHKDE MFGHGAAFDW RRTPK TFHG TLDSFQDSTY RPPAANNNAY RGQYPHVPIY EKEKSEADKI AA

+
Macromolecule #58: NDUFV2

MacromoleculeName: NDUFV2 / type: protein_or_peptide / ID: 58 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 25.189109 KDa
SequenceString: (UNK)(UNK)(UNK)(UNK)HIEWHN VRNAASDPFD FLPELYPEVY KILAKFPETK QQSAIIPLLH LAQRQNGGWV PLPG MLKIA EICEVPQKRV FECATFYCMF NHKPVGKYHI QVCVTTPCMI RGADEILHGL CHHLGVGEEE VTADGLFSIC EMECM GACV HAPMICISDY ...String:
(UNK)(UNK)(UNK)(UNK)HIEWHN VRNAASDPFD FLPELYPEVY KILAKFPETK QQSAIIPLLH LAQRQNGGWV PLPG MLKIA EICEVPQKRV FECATFYCMF NHKPVGKYHI QVCVTTPCMI RGADEILHGL CHHLGVGEEE VTADGLFSIC EMECM GACV HAPMICISDY SNPPNYRYDY IEDLTLEQAI EVVDNLKKGI YPKVGSQQGR ASAIPLAGRT SLFDPPRGPF CRDLDK A

+
Macromolecule #59: NDUEG7

MacromoleculeName: NDUEG7 / type: protein_or_peptide / ID: 59 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Euglena gracilis (euglena)
Molecular weightTheoretical: 26.818773 KDa
SequenceString: QKLLPKISCK YLALFLGLAG ATTALGFGLA PPTELVQGKI KSAELQVGDL LTYKDGGHAK CHIKEHWAVY LGTGEEIAQL VGQDAAALK LQPEERYIGH RLANTHHEEP VVRIDPLSTA RPPQGGALYK AEAPALGEPE DREAIVKGIL ARRAEKDGSL A AKNCQHFS ...String:
QKLLPKISCK YLALFLGLAG ATTALGFGLA PPTELVQGKI KSAELQVGDL LTYKDGGHAK CHIKEHWAVY LGTGEEIAQL VGQDAAALK LQPEERYIGH RLANTHHEEP VVRIDPLSTA RPPQGGALYK AEAPALGEPE DREAIVKGIL ARRAEKDGSL A AKNCQHFS TWARYQYPYS NDSLETSSRF IVTRAGATAA AVFLGTLAVS QAPLFSTMFG AMGWMVGIFR PICNRQKVVT LQ KWEVEQ

+
Macromolecule #60: FE2/S2 (INORGANIC) CLUSTER

MacromoleculeName: FE2/S2 (INORGANIC) CLUSTER / type: ligand / ID: 60 / Number of copies: 2 / Formula: FES
Molecular weightTheoretical: 175.82 Da
Chemical component information

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER / Iron–sulfur cluster

+
Macromolecule #61: IRON/SULFUR CLUSTER

MacromoleculeName: IRON/SULFUR CLUSTER / type: ligand / ID: 61 / Number of copies: 6 / Formula: SF4
Molecular weightTheoretical: 351.64 Da
Chemical component information

ChemComp-FS1:
IRON/SULFUR CLUSTER / Iron–sulfur cluster

+
Macromolecule #62: POTASSIUM ION

MacromoleculeName: POTASSIUM ION / type: ligand / ID: 62 / Number of copies: 1 / Formula: K
Molecular weightTheoretical: 39.098 Da

+
Macromolecule #63: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE

MacromoleculeName: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE / type: ligand / ID: 63 / Number of copies: 26 / Formula: PC1
Molecular weightTheoretical: 790.145 Da
Chemical component information

ChemComp-PC1:
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE / phospholipid*YM / Phosphatidylcholine

+
Macromolecule #64: CARDIOLIPIN

MacromoleculeName: CARDIOLIPIN / type: ligand / ID: 64 / Number of copies: 18 / Formula: CDL
Molecular weightTheoretical: 1.464043 KDa
Chemical component information

ChemComp-CDL:
CARDIOLIPIN / phospholipid*YM / Cardiolipin

+
Macromolecule #65: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

MacromoleculeName: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
type: ligand / ID: 65 / Number of copies: 1 / Formula: NDP
Molecular weightTheoretical: 745.421 Da
Chemical component information

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE / Nicotinamide adenine dinucleotide phosphate

+
Macromolecule #66: S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-b...

MacromoleculeName: S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate
type: ligand / ID: 66 / Number of copies: 2 / Formula: ZMP
Molecular weightTheoretical: 568.704 Da
Chemical component information

ChemComp-ZMP:
S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate

+
Macromolecule #67: 1,2-Distearoyl-sn-glycerophosphoethanolamine

MacromoleculeName: 1,2-Distearoyl-sn-glycerophosphoethanolamine / type: ligand / ID: 67 / Number of copies: 4 / Formula: 3PE
Molecular weightTheoretical: 748.065 Da
Chemical component information

ChemComp-3PE:
1,2-Distearoyl-sn-glycerophosphoethanolamine / phospholipid*YM / Phosphatidylethanolamine

+
Macromolecule #68: UBIQUINONE-10

MacromoleculeName: UBIQUINONE-10 / type: ligand / ID: 68 / Number of copies: 1 / Formula: U10
Molecular weightTheoretical: 863.343 Da
Chemical component information

ChemComp-U10:
UBIQUINONE-10 / Coenzyme Q10

+
Macromolecule #69: ZINC ION

MacromoleculeName: ZINC ION / type: ligand / ID: 69 / Number of copies: 2 / Formula: ZN
Molecular weightTheoretical: 65.409 Da

+
Macromolecule #70: FLAVIN MONONUCLEOTIDE

MacromoleculeName: FLAVIN MONONUCLEOTIDE / type: ligand / ID: 70 / Number of copies: 1 / Formula: FMN
Molecular weightTheoretical: 456.344 Da
Chemical component information

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE / Flavin mononucleotide

+
Macromolecule #71: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE

MacromoleculeName: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE / type: ligand / ID: 71 / Number of copies: 1 / Formula: NAI
Molecular weightTheoretical: 665.441 Da
Chemical component information

ChemComp-NAI:
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE / Nicotinamide adenine dinucleotide

-
Experimental details

-
Structure determination

Methodcryo EM
Processingsingle particle reconstruction
Aggregation stateparticle

-
Sample preparation

Concentration3.5 mg/mL
BufferpH: 7.4
Component:
ConcentrationFormulaName
30.0 mMTrisTrimethylsilyl
200.0 mMNaClSodium chlorideSodium chloride
1.0 mMEDTAEthylenediaminetetraacetic acidEthylene diamine tetraacetic acid
0.002 %PMSFPhenylmethylsulfonyl fluoridePMSF
0.001 %CHSCholesteryl hemisuccinate
0.007 %LMNGLauryl maltose neopentyl glycol

Details: SEC-Q buffer (30 mM Tris pH 7.4, 200 mM NaCl, 1mM EDTA, 0.002% PMSF (w/v), 0.001% CHS (w/v), 0.007% LMNG (w/v))
GridModel: Quantifoil R0.6/1 / Material: COPPER / Mesh: 300 / Pretreatment - Type: GLOW DISCHARGE / Pretreatment - Time: 120 sec. / Pretreatment - Atmosphere: AIR / Pretreatment - Pressure: 0.039 kPa / Details: 25mA
VitrificationCryogen name: ETHANE / Chamber humidity: 100 % / Chamber temperature: 277.15 K / Instrument: FEI VITROBOT MARK IV

-
Electron microscopy

MicroscopeFEI TITAN KRIOS
Electron beamAcceleration voltage: 300 kV / Electron source: FIELD EMISSION GUN
Electron opticsIllumination mode: FLOOD BEAM / Imaging mode: BRIGHT FIELDBright-field microscopy / Cs: 2.7 mm / Nominal defocus max: 2.0 µm / Nominal defocus min: 0.8 µm / Nominal magnification: 130000
Sample stageSpecimen holder model: FEI TITAN KRIOS AUTOGRID HOLDER / Cooling holder cryogen: NITROGEN
Image recordingFilm or detector model: FEI FALCON IV (4k x 4k) / Digitization - Dimensions - Width: 4096 pixel / Digitization - Dimensions - Height: 4096 pixel / Number grids imaged: 1 / Number real images: 2949 / Average exposure time: 7.0 sec. / Average electron dose: 61.5 e/Å2
Experimental equipment
Model: Titan Krios / Image courtesy: FEI Company

-
Image processing

Particle selectionNumber selected: 468732
Startup modelType of model: INSILICO MODEL
In silico model: 3D ab-inito model reconstruction in cryosparc
Initial angle assignmentType: COMMON LINE / Software - Name: cryoSPARC (ver. v3.3.2)
Final 3D classificationNumber classes: 1 / Avg.num./class: 76643 / Software - Name: cryoSPARC (ver. v3.3.2)
Final angle assignmentType: COMMON LINE / Software - Name: cryoSPARC (ver. v3.3.2)
Final reconstructionNumber classes used: 1 / Applied symmetry - Point group: C1 (asymmetric) / Algorithm: FOURIER SPACE / Resolution.type: BY AUTHOR / Resolution: 3.03 Å / Resolution method: FSC 0.143 CUT-OFF / Software - Name: cryoSPARC (ver. v3.3.2) / Number images used: 76643
FSC plot (resolution estimation)

-
Atomic model buiding 1

RefinementSpace: REAL / Protocol: RIGID BODY FIT
Output model

PDB-8j9j:
Cryo-EM structure of Euglena gracilis complex I, NADH state

+
About Yorodumi

-
News

-
Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

  • Version 3 of the EMDB header file is now the official format.
  • The previous official version 1.9 will be removed from the archive.

Related info.:EMDB header

External links:wwPDB to switch to version 3 of the EMDB data model

-
Aug 12, 2020. Covid-19 info

Covid-19 info

URL: https://pdbj.org/emnavi/covid19.php

New page: Covid-19 featured information page in EM Navigator.

Related info.:Covid-19 info / Mar 5, 2020. Novel coronavirus structure data

+
Mar 5, 2020. Novel coronavirus structure data

Novel coronavirus structure data

Related info.:Yorodumi Speices / Aug 12, 2020. Covid-19 info

External links:COVID-19 featured content - PDBj / Molecule of the Month (242)：Coronavirus Proteases

+
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)

EMDB accession codes are about to change! (news from PDBe EMDB page)

  • The allocation of 4 digits for EMDB accession codes will soon come to an end. Whilst these codes will remain in use, new EMDB accession codes will include an additional digit and will expand incrementally as the available range of codes is exhausted. The current 4-digit format prefixed with “EMD-” (i.e. EMD-XXXX) will advance to a 5-digit format (i.e. EMD-XXXXX), and so on. It is currently estimated that the 4-digit codes will be depleted around Spring 2019, at which point the 5-digit format will come into force.
  • The EM Navigator/Yorodumi systems omit the EMD- prefix.

Related info.:Q: What is EMD? / ID/Accession-code notation in Yorodumi/EM Navigator

External links:EMDB Accession Codes are Changing Soon! / Contact to PDBj

+
Jul 12, 2017. Major update of PDB

Major update of PDB

  • wwPDB released updated PDB data conforming to the new PDBx/mmCIF dictionary.
  • This is a major update changing the version number from 4 to 5, and with Remediation, in which all the entries are updated.
  • In this update, many items about electron microscopy experimental information are reorganized (e.g. em_software).
  • Now, EM Navigator and Yorodumi are based on the updated data.

External links:wwPDB Remediation / Enriched Model Files Conforming to OneDep Data Standards Now Available in the PDB FTP Archive

-
Yorodumi

Thousand views of thousand structures

  • Yorodumi is a browser for structure data from EMDB, PDB, SASBDB, etc.
  • This page is also the successor to EM Navigator detail page, and also detail information page/front-end page for Omokage search.
  • The word "yorodu" (or yorozu) is an old Japanese word meaning "ten thousand". "mi" (miru) is to see.

Related info.:EMDB / PDB / SASBDB / Comparison of 3 databanks / Yorodumi Search / Aug 31, 2016. New EM Navigator & Yorodumi / Yorodumi Papers / Jmol/JSmol / Function and homology information / Changes in new EM Navigator and Yorodumi

Read more