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- EMDB-35672: human nuclear pre-60S ribosomal particle - State A -

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基本情報

登録情報
データベース: EMDB / ID: EMD-35672
タイトルhuman nuclear pre-60S ribosomal particle - State A
マップデータhuman nuclear pre-60S ribosomal particle - Stata A - post-precessed
試料
  • 複合体: cryo-EM structure of human nuclear pre-60S ribosomal particle - State A
    • タンパク質・ペプチド: x 50種
    • RNA: x 3種
  • リガンド: x 2種
キーワードGNL2 / nuclear / pre-60S / RIBOSOME
機能・相同性
機能・相同性情報


RNA 2'-O-methyltransferase activity / mitotic nuclear division / positive regulation of protein localization to chromosome, telomeric region / : / rRNA (uridine-2'-O-ribose)-methyltransferase activity / dendrite extension / rRNA (guanine) methyltransferase activity / inner cell mass cell differentiation / hematopoietic stem cell homeostasis / preribosome binding ...RNA 2'-O-methyltransferase activity / mitotic nuclear division / positive regulation of protein localization to chromosome, telomeric region / : / rRNA (uridine-2'-O-ribose)-methyltransferase activity / dendrite extension / rRNA (guanine) methyltransferase activity / inner cell mass cell differentiation / hematopoietic stem cell homeostasis / preribosome binding / lamin filament / regulation of Notch signaling pathway / RNA methylation / regulation of megakaryocyte differentiation / regulation of fatty acid biosynthetic process / miRNA-mediated post-transcriptional gene silencing / negative regulation of G2/M transition of mitotic cell cycle / positive regulation of protein sumoylation / miRNA-mediated gene silencing by inhibition of translation / translation at presynapse / maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / protein localization to nucleolus / negative regulation of mitotic cell cycle / regulation of translation involved in cellular response to UV / eukaryotic 80S initiation complex / negative regulation of formation of translation preinitiation complex / rRNA methylation / axial mesoderm development / ribosomal protein import into nucleus / regulation of G1 to G0 transition / protein-DNA complex disassembly / positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator / 90S preribosome assembly / alpha-beta T cell differentiation / regulation of glycolytic process / skeletal system morphogenesis / positive regulation of DNA damage response, signal transduction by p53 class mediator / GAIT complex / negative regulation of cell-cell adhesion / TORC2 complex binding / regulation of reactive oxygen species metabolic process / maturation of 5.8S rRNA / stem cell division / G1 to G0 transition / mitotic metaphase chromosome alignment / preribosome, small subunit precursor / middle ear morphogenesis / cytoplasmic side of rough endoplasmic reticulum membrane / stem cell population maintenance / negative regulation of DNA replication / positive regulation of dendritic spine development / ribosomal large subunit binding / homeostatic process / preribosome, large subunit precursor / macrophage chemotaxis / lung morphogenesis / positive regulation of telomere maintenance / positive regulation of natural killer cell proliferation / Protein hydroxylation / nuclear-transcribed mRNA catabolic process / Peptide chain elongation / Selenocysteine synthesis / Formation of a pool of free 40S subunits / Eukaryotic Translation Termination / blastocyst development / ubiquitin ligase inhibitor activity / SRP-dependent cotranslational protein targeting to membrane / Response of EIF2AK4 (GCN2) to amino acid deficiency / Viral mRNA Translation / positive regulation of signal transduction by p53 class mediator / protein localization to nucleus / negative regulation of ubiquitin-dependent protein catabolic process / somitogenesis / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / hematopoietic progenitor cell differentiation / GTP hydrolysis and joining of the 60S ribosomal subunit / ribosomal subunit export from nucleus / L13a-mediated translational silencing of Ceruloplasmin expression / protein targeting / Major pathway of rRNA processing in the nucleolus and cytosol / protein-RNA complex assembly / maturation of LSU-rRNA / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / Notch signaling pathway / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / rough endoplasmic reticulum / translation initiation factor activity / MDM2/MDM4 family protein binding / negative regulation of protein ubiquitination / negative regulation of proteasomal ubiquitin-dependent protein catabolic process / cellular response to interleukin-4 / cytosolic ribosome / ossification / 転移酵素; 一炭素原子の基を移すもの; メチル基を移すもの / negative regulation of cell migration / regulation of signal transduction by p53 class mediator / cytosolic ribosome assembly / ribosomal large subunit biogenesis / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / condensed nuclear chromosome
類似検索 - 分子機能
Coiled-coil domain-containing protein 86 / Ribosome biogenesis protein Rpf2 / Learning associated protein 18-like / LLP homolog / Ribosomal RNA methyltransferase, SPB1-like, C-terminal / Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 / AdoMet-dependent rRNA methyltransferase SPB1-like / Spb1 C-terminal domain / Ribosomal RNA methyltransferase Spb1, DUF3381 / Ribosomal biogenesis regulatory protein ...Coiled-coil domain-containing protein 86 / Ribosome biogenesis protein Rpf2 / Learning associated protein 18-like / LLP homolog / Ribosomal RNA methyltransferase, SPB1-like, C-terminal / Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 / AdoMet-dependent rRNA methyltransferase SPB1-like / Spb1 C-terminal domain / Ribosomal RNA methyltransferase Spb1, DUF3381 / Ribosomal biogenesis regulatory protein / Ribosome biogenesis regulatory protein (RRS1) / : / Ribosomal RNA large subunit methyltransferase E / Nucleolar GTP-binding protein 2, N-terminal domain / Nucleolar GTP-binding protein 2 / NGP1NT (NUC091) domain / NLE / NLE (NUC135) domain / Guanine nucleotide-binding protein-like 3, N-terminal domain / GNL3L/Grn1 putative GTPase / : / Ribosomal biogenesis NSA2 family / GTP-binding protein, orthogonal bundle domain superfamily / Ribosome assembly factor Mrt4 / : / : / NOG, C-terminal / Nucleolar GTP-binding protein 1 / NOGCT (NUC087) domain / Nucleolar GTP-binding protein 1, Rossman-fold domain / NOG1, N-terminal helical domain / Nucleolar GTP-binding protein 1 (NOG1) / NOG1 N-terminal helical domain / Circularly permuted (CP)-type guanine nucleotide-binding (G) domain / Circularly permuted (CP)-type guanine nucleotide-binding (G) domain profile. / Brix domain / Brix domain / Brix domain profile. / Brix / OBG-type guanine nucleotide-binding (G) domain / OBG-type guanine nucleotide-binding (G) domain profile. / Translation initiation factor IF6 / eIF-6 family / translation initiation factor 6 / 50S ribosome-binding GTPase / GTP binding domain / Ribosomal protein L6, N-terminal / Ribosomal protein L6, N-terminal domain / 50S ribosomal protein L10, insertion domain superfamily / Ribosomal protein L30e / Ribosomal L15/L27a, N-terminal / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P / Ribosomal protein L28e / : / Ribosomal protein L23 / Ribosomal protein L2, archaeal-type / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / metallochaperone-like domain / TRASH domain / Ribosomal protein L13e, conserved site / Ribosomal protein L13e signature. / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein L13e / Ribosomal protein L13e / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / Ribosomal protein L19, eukaryotic / : / Ribosomal protein L19/L19e conserved site / Ribosomal protein L19e signature. / Ribosomal protein L6e signature. / 60S ribosomal protein L18a/ L20, eukaryotes / Ribosomal protein L24e, conserved site / Ribosomal protein L24e signature. / Ribosomal protein L18/L18-A/B/e, conserved site / Ribosomal protein L18e signature. / Ribosomal protein L34e, conserved site / Ribosomal protein L34e signature. / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein L23/L25, N-terminal / Ribosomal protein L23, N-terminal domain / Ribosomal protein L30e signature 1. / Ribosomal protein L36e signature. / 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a / Ribosomal protein L35Ae, conserved site / Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A / Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A / Ribosomal protein 60S L18 and 50S L18e / Ribosomal protein L35Ae signature. / Eukaryotic Ribosomal Protein L27, KOW domain / Ribosomal protein L27e / Ribosomal protein L27e superfamily
類似検索 - ドメイン・相同性
Ribosome biogenesis protein NSA2 homolog / Large ribosomal subunit protein eL33 / Large ribosomal subunit protein uL30 / Large ribosomal subunit protein uL22 / Large ribosomal subunit protein eL13 / Large ribosomal subunit protein uL11 / Large ribosomal subunit protein uL6 / Large ribosomal subunit protein eL22 / Large ribosomal subunit protein uL4 / Large ribosomal subunit protein uL3 ...Ribosome biogenesis protein NSA2 homolog / Large ribosomal subunit protein eL33 / Large ribosomal subunit protein uL30 / Large ribosomal subunit protein uL22 / Large ribosomal subunit protein eL13 / Large ribosomal subunit protein uL11 / Large ribosomal subunit protein uL6 / Large ribosomal subunit protein eL22 / Large ribosomal subunit protein uL4 / Large ribosomal subunit protein uL3 / Large ribosomal subunit protein uL13 / Large ribosomal subunit protein uL29 / Large ribosomal subunit protein uL15 / Large ribosomal subunit protein uL18 / Large ribosomal subunit protein eL21 / Large ribosomal subunit protein eL28 / Large ribosomal subunit protein eL34 / Large ribosomal subunit protein eL14 / Eukaryotic translation initiation factor 6 / Large ribosomal subunit protein uL24 / Large ribosomal subunit protein eL15 / Large ribosomal subunit protein eL27 / Large ribosomal subunit protein eL43 / Large ribosomal subunit protein eL37 / Large ribosomal subunit protein eL8 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein uL14 / Large ribosomal subunit protein eL30 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein eL31 / Large ribosomal subunit protein eL32 / Large ribosomal subunit protein uL5 / Large ribosomal subunit protein uL2 / Large ribosomal subunit protein eL38 / Large ribosomal subunit protein eL19 / Large ribosomal subunit protein eL20 / Large ribosomal subunit protein eL6 / Large ribosomal subunit protein eL18 / Nucleolar GTP-binding protein 2 / Ribosome biogenesis regulatory protein homolog / pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 / Protein LLP homolog / Guanine nucleotide-binding protein-like 3 / GTP-binding protein 4 / Coiled-coil domain-containing protein 86 / Ribosome production factor 2 homolog / Notchless protein homolog 1 / Probable ribosome biogenesis protein RLP24 / mRNA turnover protein 4 homolog / Large ribosomal subunit protein eL36
類似検索 - 構成要素
生物種Homo sapiens (ヒト)
手法単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.3 Å
データ登録者Zhang Y / Gao N
資金援助 中国, 1件
OrganizationGrant number国
National Science Foundation (NSF, China)32230051;31922036 中国
引用ジャーナル: Cell Res / 年: 2023
タイトル: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
著者: Yunyang Zhang / Xiaomeng Liang / Sha Luo / Yan Chen / Yu Li / Chengying Ma / Ningning Li / Ning Gao /
要旨: Eukaryotic ribosome assembly is a highly orchestrated process that involves over two hundred protein factors. After early assembly events on nascent rRNA in the nucleolus, pre-60S particles undergo ...Eukaryotic ribosome assembly is a highly orchestrated process that involves over two hundred protein factors. After early assembly events on nascent rRNA in the nucleolus, pre-60S particles undergo continuous maturation steps in the nucleoplasm, and prepare for nuclear export. Here, we report eleven cryo-EM structures of the nuclear pre-60S particles isolated from human cells through epitope-tagged GNL2, at resolutions of 2.8-4.3 Å. These high-resolution snapshots provide fine details for several major structural remodeling events at a virtual temporal resolution. Two new human nuclear factors, L10K and C11orf98, were also identified. Comparative structural analyses reveal that many assembly factors act as successive place holders to control the timing of factor association/dissociation events. They display multi-phasic binding properties for different domains and generate complex binding inter-dependencies as a means to guide the rRNA maturation process towards its mature conformation. Overall, our data reveal that nuclear assembly of human pre-60S particles is generally hierarchical with short branch pathways, and a few factors display specific roles as rRNA chaperones by confining rRNA helices locally to facilitate their folding, such as the C-terminal domain of SDAD1.
履歴
登録2023年3月17日-
ヘッダ(付随情報) 公開2023年8月9日-
マップ公開2023年8月9日-
更新2025年9月17日-
現状2025年9月17日処理サイト: PDBj / 状態: 公開

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構造の表示

添付画像

emd_35672.png

ダウンロードとリンク

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マップ

ファイルダウンロード / ファイル: emd_35672.map.gz / 形式: CCP4 / 大きさ: 244.1 MB / タイプ: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
注釈human nuclear pre-60S ribosomal particle - Stata A - post-precessed
投影像・断面図

画像のコントロール

大きさ
明度
コントラスト
その他
軸Z (Sec.)Y (Row.)X (Col.)
1.37 Å/pix.
x 400 pix.
= 548. Å		1.37 Å/pix.
x 400 pix.
= 548. Å		1.37 Å/pix.
x 400 pix.
= 548. Å

表面

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断面 (1/3)

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画像は Spider により作成

ボクセルのサイズX=Y=Z: 1.37 Å
密度

ヒストグラム

ヒストグラム (対数)
表面レベル登録者による: 0.038
最小 - 最大-0.048906893 - 0.17304762
平均 (標準偏差)0.00073353946 (±0.0053937957)
対称性空間群: 1
詳細

EMDB XML:

マップ形状
Axis orderXYZ
Origin000
サイズ400400400
Spacing400400400
セルA=B=C: 548.0 Å
α=β=γ: 90.0 °

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添付データ

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ハーフマップ: human nuclear pre-60S ribosomal particle - Stata A - half1

ファイルemd_35672_half_map_1.map
注釈human nuclear pre-60S ribosomal particle - Stata A - half1
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軸ZYX

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密度ヒストグラム

ヒストグラム

ヒストグラム (対数)

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ハーフマップ: human nuclear pre-60S ribosomal particle - Stata A - half2

ファイルemd_35672_half_map_2.map
注釈human nuclear pre-60S ribosomal particle - Stata A - half2
投影像・断面図
軸ZYX

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密度ヒストグラム

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試料の構成要素

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全体 : cryo-EM structure of human nuclear pre-60S ribosomal particle - S...

全体名称: cryo-EM structure of human nuclear pre-60S ribosomal particle - State A
要素
  • 複合体: cryo-EM structure of human nuclear pre-60S ribosomal particle - State A
    • タンパク質・ペプチド: 60S ribosomal protein L12
    • タンパク質・ペプチド: GTP-binding protein 4
    • タンパク質・ペプチド: Eukaryotic translation initiation factor 6
    • タンパク質・ペプチド: Probable ribosome biogenesis protein RLP24
    • タンパク質・ペプチド: 60S ribosomal protein L3
    • タンパク質・ペプチド: 60S ribosomal protein L4
    • タンパク質・ペプチド: 60S ribosomal protein L30
    • タンパク質・ペプチド: 60S ribosomal protein L34
    • タンパク質・ペプチド: 60S ribosomal protein L7a
    • タンパク質・ペプチド: 60S ribosomal protein L35
    • タンパク質・ペプチド: 60S ribosomal protein L9
    • タンパク質・ペプチド: 60S ribosomal protein L36
    • タンパク質・ペプチド: 60S ribosomal protein L27a
    • タンパク質・ペプチド: 60S ribosomal protein L37
    • タンパク質・ペプチド: 60S ribosomal protein L39
    • タンパク質・ペプチド: 60S ribosomal protein L13
    • タンパク質・ペプチド: 60S ribosomal protein L14
    • タンパク質・ペプチド: 60S ribosomal protein L15
    • タンパク質・ペプチド: 60S ribosomal protein L13a
    • タンパク質・ペプチド: 60S ribosomal protein L37a
    • タンパク質・ペプチド: 60S ribosomal protein L18
    • タンパク質・ペプチド: 60S ribosomal protein L19
    • タンパク質・ペプチド: 60S ribosomal protein L18a
    • タンパク質・ペプチド: 60S ribosomal protein L21
    • タンパク質・ペプチド: 60S ribosomal protein L23
    • タンパク質・ペプチド: 60S ribosomal protein L26
    • タンパク質・ペプチド: 60S ribosomal protein L27
    • タンパク質・ペプチド: 60S ribosomal protein L28
    • タンパク質・ペプチド: 60S ribosomal protein L8
    • タンパク質・ペプチド: 60S ribosomal protein L35a
    • タンパク質・ペプチド: 60S ribosomal protein L6
    • タンパク質・ペプチド: 60S ribosomal protein L7
    • タンパク質・ペプチド: Protein LLP homolog
    • タンパク質・ペプチド: 60S ribosomal protein L11
    • タンパク質・ペプチド: 60S ribosomal protein L5
    • タンパク質・ペプチド: Ribosome biogenesis protein NSA2 homolog
    • タンパク質・ペプチド: Notchless protein homolog 1
    • タンパク質・ペプチド: Ribosome biogenesis regulatory protein homolog
    • タンパク質・ペプチド: Guanine nucleotide-binding protein-like 3
    • タンパク質・ペプチド: mRNA turnover protein 4 homolog
    • タンパク質・ペプチド: G Protein Nucleolar 2
    • タンパク質・ペプチド: Coiled-coil domain-containing protein 86
    • RNA: 28S rRNA
    • RNA: 5.8S rRMA
    • タンパク質・ペプチド: 60S ribosomal protein L23a
    • タンパク質・ペプチド: pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3
    • タンパク質・ペプチド: 60S ribosomal protein L22
    • タンパク質・ペプチド: 60S ribosomal protein L31
    • タンパク質・ペプチド: 60S ribosomal protein L32
    • タンパク質・ペプチド: 60S ribosomal protein L17
    • タンパク質・ペプチド: 60S ribosomal protein L38
    • RNA: 5S RNA
    • タンパク質・ペプチド: Ribosome production factor 2 homolog
  • リガンド: GUANOSINE-5'-TRIPHOSPHATE
  • リガンド: MAGNESIUM ION

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超分子 #1: cryo-EM structure of human nuclear pre-60S ribosomal particle - S...

超分子名称: cryo-EM structure of human nuclear pre-60S ribosomal particle - State A
タイプ: complex / ID: 1 / 親要素: 0 / 含まれる分子: #1-#45, #53, #46-#52
由来(天然)生物種: Homo sapiens (ヒト)

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分子 #1: 60S ribosomal protein L12

分子名称: 60S ribosomal protein L12 / タイプ: protein_or_peptide / ID: 1 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 17.847619 KDa
配列文字列:
MPPKFDPNEI KVVYLRCTGG EVGATSALAP KIGPLGLSPK KVGDDIAKAT GDWKGLRITV KLTIQNRQAQ IEVVPSASAL IIKALKEPP RDRKKQKNIK HSGNITFDEI VNIARQMRHR SLARELSGTI KEILGTAQSV GCNVDGRHPH DIIDDINSGA V ECPAS

UniProtKB: Large ribosomal subunit protein uL11

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分子 #2: GTP-binding protein 4

分子名称: GTP-binding protein 4 / タイプ: protein_or_peptide / ID: 2 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 74.10782 KDa
配列文字列: MAHYNFKKIT VVPSAKDFID LTLSKTQRKT PTVIHKHYQI HRIRHFYMRK VKFTQQNYHD RLSQILTDFP KLDDIHPFYA DLMNILYDK DHYKLALGQI NIAKNLVDNV AKDYVRLMKY GDSLYRCKQL KRAALGRMCT VIKRQKQSLE YLEQVRQHLS R LPTIDPNT ...文字列:
MAHYNFKKIT VVPSAKDFID LTLSKTQRKT PTVIHKHYQI HRIRHFYMRK VKFTQQNYHD RLSQILTDFP KLDDIHPFYA DLMNILYDK DHYKLALGQI NIAKNLVDNV AKDYVRLMKY GDSLYRCKQL KRAALGRMCT VIKRQKQSLE YLEQVRQHLS R LPTIDPNT RTLLLCGYPN VGKSSFINKV TRADVDVQPY AFTTKSLFVG HMDYKYLRWQ VVDTPGILDH PLEDRNTIEM QA ITALAHL RAAVLYVMDL SEQCGHGLRE QLELFQNIRP LFINKPLIVV ANKCDVKRIA ELSEDDQKIF TDLQSEGFPV IET STLTEE GVIKVKTEAC DRLLAHRVET KMKGNKVNEV LNRLHLAIPT RRDDKERPPF IPEGVVARRK RMETEESRKK RERD LELEM GDDYILDLQK YWDLMNLSEK HDKIPEIWEG HNIADYIDPA IMKKLEELEK EEELRTAAGE YDSVSESEDE EMLEI RQLA KQIREKKKLK ILESKEKNTQ GPRMPRTAKK VQRTVLEKEM RSLGVDMDDK DDAHYAVQAR RSRSITRKRK REDSAP PSS VARSGSCSRT PRDVSGLRDV KMVKKAKTMM KNAQKKMNRL GKKGEADRHV FDMKPKHLLS GKRKAGKKDR R

UniProtKB: GTP-binding protein 4

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分子 #3: Eukaryotic translation initiation factor 6

分子名称: Eukaryotic translation initiation factor 6 / タイプ: protein_or_peptide / ID: 3 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 26.62001 KDa
配列文字列: MAVRASFENN CEIGCFAKLT NTYCLVAIGG SENFYSVFEG ELSDTIPVVH ASIAGCRIIG RMCVGNRHGL LVPNNTTDQE LQHIRNSLP DTVQIRRVEE RLSALGNVTT CNDYVALVHP DLDRETEEIL ADVLKVEVFR QTVADQVLVG SYCVFSNQGG L VHPKTSIE ...文字列:
MAVRASFENN CEIGCFAKLT NTYCLVAIGG SENFYSVFEG ELSDTIPVVH ASIAGCRIIG RMCVGNRHGL LVPNNTTDQE LQHIRNSLP DTVQIRRVEE RLSALGNVTT CNDYVALVHP DLDRETEEIL ADVLKVEVFR QTVADQVLVG SYCVFSNQGG L VHPKTSIE DQDELSSLLQ VPLVAGTVNR GSEVIAAGMV VNDWCAFCGL DTTSTELSVV ESVFKLNEAQ PSTIATSMRD SL IDSLT

UniProtKB: Eukaryotic translation initiation factor 6

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分子 #4: Probable ribosome biogenesis protein RLP24

分子名称: Probable ribosome biogenesis protein RLP24 / タイプ: protein_or_peptide / ID: 4 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 19.666258 KDa
配列文字列:
MRIEKCYFCS GPIYPGHGMM FVRNDCKVFR FCKSKCHKNF KKKRNPRKVR WTKAFRKAAG KELTVDNSFE FEKRRNEPIK YQRELWNKT IDAMKRVEEI KQKRQAKFIM NRLKKNKELQ KVQDIKEVKQ NIHLIRAPLA GKGKQLEEKM VQQLQEDVDM E DAP

UniProtKB: Probable ribosome biogenesis protein RLP24

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分子 #5: 60S ribosomal protein L3

分子名称: 60S ribosomal protein L3 / タイプ: protein_or_peptide / ID: 5 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 46.211113 KDa
配列文字列: MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGI VGYVETPRGL RTFKTVFAEH ISDECKRRFY KNWHKSKKKA FTKYCKKWQD EDGKKQLEKD FSSMKKYCQV I RVIAHTQM ...文字列:
MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGI VGYVETPRGL RTFKTVFAEH ISDECKRRFY KNWHKSKKKA FTKYCKKWQD EDGKKQLEKD FSSMKKYCQV I RVIAHTQM RLLPLRQKKA HLMEIQVNGG TVAEKLDWAR ERLEQQVPVN QVFGQDEMID VIGVTKGKGY KGVTSRWHTK KL PRKTHRG LRKVACIGAW HPARVAFSVA RAGQKGYHHR TEINKKIYKI GQGYLIKDGK LIKNNASTDY DLSDKSINPL GGF VHYGEV TNDFVMLKGC VVGTKKRVLT LRKSLLVQTK RRALEKIDLK FIDTTSKFGH GRFQTMEEKK AFMGPLKKDR IAKE EGA

UniProtKB: Large ribosomal subunit protein uL3

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分子 #6: 60S ribosomal protein L4

分子名称: 60S ribosomal protein L4 / タイプ: protein_or_peptide / ID: 6 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 47.804621 KDa
配列文字列: MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH QTSAESWGTG RAVARIPRVR GGGTHRSGQ GAFGNMCRGG RMFAPTKTWR RWHRRVNTTQ KRYAICSALA ASALPALVMS KGHRIEEVPE LPLVVEDKVE G YKKTKEAV ...文字列:
MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH QTSAESWGTG RAVARIPRVR GGGTHRSGQ GAFGNMCRGG RMFAPTKTWR RWHRRVNTTQ KRYAICSALA ASALPALVMS KGHRIEEVPE LPLVVEDKVE G YKKTKEAV LLLKKLKAWN DIKKVYASQR MRAGKGKMRN RRRIQRRGPC IIYNEDNGII KAFRNIPGIT LLNVSKLNIL KL APGGHVG RFCIWTESAF RKLDELYGTW RKAASLKSNY NLPMHKMINT DLSRILKSPE IQRALRAPRK KIHRRVLKKN PLK NLRIML KLNPYAKTMR RNTILRQARN HKLRVDKAAA AAAALQAKSD EKAAVAGKKP VVGKKGKKAA VGVKKQKKPL VGKK AAATK KPAPEKKPAE KKPTTEEKKP AA

UniProtKB: Large ribosomal subunit protein uL4

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分子 #7: 60S ribosomal protein L30

分子名称: 60S ribosomal protein L30 / タイプ: protein_or_peptide / ID: 7 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 12.805092 KDa
配列文字列:
MVAAKKTKKS LESINSRLQL VMKSGKYVLG YKQTLKMIRQ GKAKLVILAN NCPALRKSEI EYYAMLAKTG VHHYSGNNIE LGTACGKYY RVCTLAIIDP GDSDIIRSMP EQTGEK

UniProtKB: Large ribosomal subunit protein eL30

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分子 #8: 60S ribosomal protein L34

分子名称: 60S ribosomal protein L34 / タイプ: protein_or_peptide / ID: 8 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 13.326074 KDa
配列文字列:
MVQRLTYRRR LSYNTASNKT RLSRTPGNRI VYLYTKKVGK APKSACGVCP GRLRGVRAVR PKVLMRLSKT KKHVSRAYGG SMCAKCVRD RIKRAFLIEE QKIVVKVLKA QAQSQKAK

UniProtKB: Large ribosomal subunit protein eL34

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分子 #9: 60S ribosomal protein L7a

分子名称: 60S ribosomal protein L7a / タイプ: protein_or_peptide / ID: 9 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 30.061785 KDa
配列文字列: MPKGKKAKGK KVAPAPAVVK KQEAKKVVNP LFEKRPKNFG IGQDIQPKRD LTRFVKWPRY IRLQRQRAIL YKRLKVPPAI NQFTQALDR QTATQLLKLA HKYRPETKQE KKQRLLARAE KKAAGKGDVP TKRPPVLRAG VNTVTTLVEN KKAQLVVIAH D VDPIELVV ...文字列:
MPKGKKAKGK KVAPAPAVVK KQEAKKVVNP LFEKRPKNFG IGQDIQPKRD LTRFVKWPRY IRLQRQRAIL YKRLKVPPAI NQFTQALDR QTATQLLKLA HKYRPETKQE KKQRLLARAE KKAAGKGDVP TKRPPVLRAG VNTVTTLVEN KKAQLVVIAH D VDPIELVV FLPALCRKMG VPYCIIKGKA RLGRLVHRKT CTTVAFTQVN SEDKGALAKL VEAIRTNYND RYDEIRRHWG GN VLGPKSV ARIAKLEKAK AKELATKLG

UniProtKB: Large ribosomal subunit protein eL8

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分子 #10: 60S ribosomal protein L35

分子名称: 60S ribosomal protein L35 / タイプ: protein_or_peptide / ID: 10 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 14.593624 KDa
配列文字列:
MAKIKARDLR GKKKEELLKQ LDDLKVELSQ LRVAKVTGGA ASKLSKIRVV RKSIARVLTV INQTQKENLR KFYKGKKYKP LDLRPKKTR AMRRRLNKHE ENLKTKKQQR KERLYPLRKY AVKA

UniProtKB: Large ribosomal subunit protein uL29

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分子 #11: 60S ribosomal protein L9

分子名称: 60S ribosomal protein L9 / タイプ: protein_or_peptide / ID: 11 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 21.899471 KDa
配列文字列: MKTILSNQTV DIPENVDITL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW WGNRKELATV RTICSHVQNM IKGVTLGFR YKMRSVYAHF PINVVIQENG SLVEIRNFLG EKYIRRVRMR PGVACSVSQA QKDELILEGN DIELVSNSAA L IQQATTVK ...文字列:
MKTILSNQTV DIPENVDITL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW WGNRKELATV RTICSHVQNM IKGVTLGFR YKMRSVYAHF PINVVIQENG SLVEIRNFLG EKYIRRVRMR PGVACSVSQA QKDELILEGN DIELVSNSAA L IQQATTVK NKDIRKFLDG IYVSEKGTVQ QADE

UniProtKB: Large ribosomal subunit protein uL6

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分子 #12: 60S ribosomal protein L36

分子名称: 60S ribosomal protein L36 / タイプ: protein_or_peptide / ID: 12 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 12.290859 KDa
配列文字列:
MALRYPMAVG LNKGHKVTKN VSKPRHSRRR GRLTKHTKFV RDMIREVCGF APYERRAMEL LKVSKDKRAL KFIKKRVGTH IRAKRKREE LSNVLAAMRK AAAKKD

UniProtKB: Large ribosomal subunit protein eL36

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分子 #13: 60S ribosomal protein L27a

分子名称: 60S ribosomal protein L27a / タイプ: protein_or_peptide / ID: 13 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 16.604535 KDa
配列文字列:
MPSRLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGLHH HRINFDKYHP GYFGKVGMKH YHLKRNQSFC PTVNLDKLWT LVSEQTRVN AAKNKTGAAP IIDVVRSGYY KVLGKGKLPK QPVIVKAKFF SRRAEEKIKS VGGACVLVA

UniProtKB: Large ribosomal subunit protein uL15

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分子 #14: 60S ribosomal protein L37

分子名称: 60S ribosomal protein L37 / タイプ: protein_or_peptide / ID: 14 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 11.111032 KDa
配列文字列:
MTKGTSSFGK RRNKTHTLCR RCGSKAYHLQ KSTCGKCGYP AKRKRKYNWS AKAKRRNTTG TGRMRHLKIV YRRFRHGFRE GTTPKPKRA AVAASSSS

UniProtKB: Large ribosomal subunit protein eL37

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分子 #15: 60S ribosomal protein L39

分子名称: 60S ribosomal protein L39 / タイプ: protein_or_peptide / ID: 15 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 6.426759 KDa
配列文字列:
MSSHKTFRIK RFLAKKQKQN RPIPQWIRMK TGNKIRYNSK RRHWRRTKLG L

UniProtKB: Large ribosomal subunit protein eL39

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分子 #16: 60S ribosomal protein L13

分子名称: 60S ribosomal protein L13 / タイプ: protein_or_peptide / ID: 16 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 24.321682 KDa
配列文字列: MAPSRNGMVL KPHFHKDWQR RVATWFNQPA RKIRRRKARQ AKARRIAPRP ASGPIRPIVR CPTVRYHTKV RAGRGFSLEE LRVAGIHKK VARTIGISVD PRRRNKSTES LQANVQRLKE YRSKLILFPR KPSAPKKGDS SAEELKLATQ LTGPVMPVRN V YKKEKARV ...文字列:
MAPSRNGMVL KPHFHKDWQR RVATWFNQPA RKIRRRKARQ AKARRIAPRP ASGPIRPIVR CPTVRYHTKV RAGRGFSLEE LRVAGIHKK VARTIGISVD PRRRNKSTES LQANVQRLKE YRSKLILFPR KPSAPKKGDS SAEELKLATQ LTGPVMPVRN V YKKEKARV ITEEEKNFKA FASLRMARAN ARLFGIRAKR AKEAAEQDVE KKK

UniProtKB: Large ribosomal subunit protein eL13

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分子 #17: 60S ribosomal protein L14

分子名称: 60S ribosomal protein L14 / タイプ: protein_or_peptide / ID: 17 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 23.485016 KDa
配列文字列: MVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTQVRRQAM PFKCMQLTDF ILKFPHSAHQ KYVRQAWQKA DINTKWAAT RWAKKIEARE RKAKMTDFDR FKVMKAKKMR NRIIKNEVKK LQKAALLKAS PKKAPGTKGT AAAAAAAAAA K VPAKKITA ...文字列:
MVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTQVRRQAM PFKCMQLTDF ILKFPHSAHQ KYVRQAWQKA DINTKWAAT RWAKKIEARE RKAKMTDFDR FKVMKAKKMR NRIIKNEVKK LQKAALLKAS PKKAPGTKGT AAAAAAAAAA K VPAKKITA ASKKAPAQKV PAQKATGQKA APAPKAQKGQ KAPAQKAPAP KASGKKA

UniProtKB: Large ribosomal subunit protein eL14

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分子 #18: 60S ribosomal protein L15

分子名称: 60S ribosomal protein L15 / タイプ: protein_or_peptide / ID: 18 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 24.207285 KDa
配列文字列: MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGV NQLKFARSLQ SVAEERAGRH CGALRVLNSY WVGEDSTYKF FEVILIDPFH KAIRRNPDTQ WITKPVHKHR E MRGLTSAG ...文字列:
MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGV NQLKFARSLQ SVAEERAGRH CGALRVLNSY WVGEDSTYKF FEVILIDPFH KAIRRNPDTQ WITKPVHKHR E MRGLTSAG RKSRGLGKGH KFHHTIGGSR RAAWRRRNTL QLHRYR

UniProtKB: Large ribosomal subunit protein eL15

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分子 #19: 60S ribosomal protein L13a

分子名称: 60S ribosomal protein L13a / タイプ: protein_or_peptide / ID: 19 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 23.633412 KDa
配列文字列: MAEVQVLVLD GRGHLLGRLA AIVAKQVLLG RKVVVVRCEG INISGNFYRN KLKYLAFLRK RMNTNPSRGP YHFRAPSRIF WRTVRGMLP HKTKRGQAAL DRLKVFDGIP PPYDKKKRMV VPAALKVVRL KPTRKFAYLG RLAHEVGWKY QAVTATLEEK R KEKAKIHY ...文字列:
MAEVQVLVLD GRGHLLGRLA AIVAKQVLLG RKVVVVRCEG INISGNFYRN KLKYLAFLRK RMNTNPSRGP YHFRAPSRIF WRTVRGMLP HKTKRGQAAL DRLKVFDGIP PPYDKKKRMV VPAALKVVRL KPTRKFAYLG RLAHEVGWKY QAVTATLEEK R KEKAKIHY RKKKQLMRLR KQAEKNVEKK IDKYTEVLKT HGLLV

UniProtKB: Large ribosomal subunit protein uL13

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分子 #20: 60S ribosomal protein L37a

分子名称: 60S ribosomal protein L37a / タイプ: protein_or_peptide / ID: 20 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 10.29935 KDa
配列文字列:
MAKRTKKVGI VGKYGTRYGA SLRKMVKKIE ISQHAKYTCS FCGKTKMKRR AVGIWHCGSC MKTVAGGAWT YNTTSAVTVK SAIRRLKEL KDQ

UniProtKB: Large ribosomal subunit protein eL43

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分子 #21: 60S ribosomal protein L18

分子名称: 60S ribosomal protein L18 / タイプ: protein_or_peptide / ID: 21 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 21.687676 KDa
配列文字列:
MGVDIRHNKD RKVRRKEPKS QDIYLRLLVK LYRFLARRTN STFNQVVLKR LFMSRTNRPP LSLSRMIRKM KLPGRENKTA VVVGTITDD VRVQEVPKLK VCALRVTSRA RSRILRAGGK ILTFDQLALD SPKGCGTVLL SGPRKGREVY RHFGKAPGTP H SHTKPYVR SKGRKFERAR GRRASRGYKN

UniProtKB: Large ribosomal subunit protein eL18

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分子 #22: 60S ribosomal protein L19

分子名称: 60S ribosomal protein L19 / タイプ: protein_or_peptide / ID: 22 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 23.535281 KDa
配列文字列: MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARM PEKVTWMRRM RILRRLLRRY RESKKIDRHM YHSLYLKVKG NVFKNKRILM EHIHKLKADK ARKKLLADQA E ARRSKTKE ...文字列:
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARM PEKVTWMRRM RILRRLLRRY RESKKIDRHM YHSLYLKVKG NVFKNKRILM EHIHKLKADK ARKKLLADQA E ARRSKTKE ARKRREERLQ AKKEEIIKTL SKEEETKK

UniProtKB: Large ribosomal subunit protein eL19

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分子 #23: 60S ribosomal protein L18a

分子名称: 60S ribosomal protein L18a / タイプ: protein_or_peptide / ID: 23 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 20.808514 KDa
配列文字列:
MKASGTLREY KVVGRCLPTP KCHTPPLYRM RIFAPNHVVA KSRFWYFVSQ LKKMKKSSGE IVYCGQVFEK SPLRVKNFGI WLRYDSRSG THNMYREYRD LTTAGAVTQC YRDMGARHRA RAHSIQIMKV EEIAASKCRR PAVKQFHDSK IKFPLPHRVL R RQHKPRFT TKRPNTFF

UniProtKB: Large ribosomal subunit protein eL20

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分子 #24: 60S ribosomal protein L21

分子名称: 60S ribosomal protein L21 / タイプ: protein_or_peptide / ID: 24 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 18.609988 KDa
配列文字列:
MTNTKGKRRG TRYMFSRPFR KHGVVPLATY MRIYKKGDIV DIKGMGTVQK GMPHKCYHGK TGRVYNVTQH AVGIVVNKQV KGKILAKRI NVRIEHIKHS KSRDSFLKRV KENDQKKKEA KEKGTWVQLK RQPAPPREAH FVRTNGKEPE LLEPIPYEFM A

UniProtKB: Large ribosomal subunit protein eL21

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分子 #25: 60S ribosomal protein L23

分子名称: 60S ribosomal protein L23 / タイプ: protein_or_peptide / ID: 25 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 14.892505 KDa
配列文字列:
MSKRGRGGSS GAKFRISLGL PVGAVINCAD NTGAKNLYII SVKGIKGRLN RLPAAGVGDM VMATVKKGKP ELRKKVHPAV VIRQRKSYR RKDGVFLYFE DNAGVIVNNK GEMKGSAITG PVAKECADLW PRIASNAGSI A

UniProtKB: Large ribosomal subunit protein uL14

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分子 #26: 60S ribosomal protein L26

分子名称: 60S ribosomal protein L26 / タイプ: protein_or_peptide / ID: 26 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 17.303363 KDa
配列文字列:
MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG HYKGQQIGKV VQVYRKKYVI YIERVQREK ANGTTVHVGI HPSKVVITRL KLDKDRKKIL ERKAKSRQVG KEKGKYKEET IEKMQE

UniProtKB: Large ribosomal subunit protein uL24

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分子 #27: 60S ribosomal protein L27

分子名称: 60S ribosomal protein L27 / タイプ: protein_or_peptide / ID: 27 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 15.835831 KDa
配列文字列:
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDI PLDKTVVNKD VFRDPALKRK ARREAKVKFE ERYKTGKNKW FFQKLRF

UniProtKB: Large ribosomal subunit protein eL27

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分子 #28: 60S ribosomal protein L28

分子名称: 60S ribosomal protein L28 / タイプ: protein_or_peptide / ID: 28 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 15.784622 KDa
配列文字列:
MSAHLQWMVV RNCSSFLIKR NKQTYSTEPN NLKARNSFRY NGLIHRKTVG VEPAADGKGV VVVIKRRSGQ RKPATSYVRT TINKNARAT LSSIRHMIRK NKYRPDLRMA AIRRASAILR SQKPVMVKRK RTRPTKSS

UniProtKB: Large ribosomal subunit protein eL28

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分子 #29: 60S ribosomal protein L8

分子名称: 60S ribosomal protein L8 / タイプ: protein_or_peptide / ID: 29 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 28.088863 KDa
配列文字列: MGRVIRGQRK GAGSVFRAHV KHRKGAARLR AVDFAERHGY IKGIVKDIIH DPGRGAPLAK VVFRDPYRFK KRTELFIAAE GIHTGQFVY CGKKAQLNIG NVLPVGTMPE GTIVCCLEEK PGDRGKLARA SGNYATVISH NPETKKTRVK LPSGSKKVIS S ANRAVVGV ...文字列:
MGRVIRGQRK GAGSVFRAHV KHRKGAARLR AVDFAERHGY IKGIVKDIIH DPGRGAPLAK VVFRDPYRFK KRTELFIAAE GIHTGQFVY CGKKAQLNIG NVLPVGTMPE GTIVCCLEEK PGDRGKLARA SGNYATVISH NPETKKTRVK LPSGSKKVIS S ANRAVVGV VAGGGRIDKP ILKAGRAYHK YKAKRNCWPR VRGVAMNPVE HPFGGGNHQH IGKPSTIRRD APAGRKVGLI AA RRTGRLR GTKTVQEKEN

UniProtKB: Large ribosomal subunit protein uL2

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分子 #30: 60S ribosomal protein L35a

分子名称: 60S ribosomal protein L35a / タイプ: protein_or_peptide / ID: 30 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 12.564743 KDa
配列文字列:
MSGRLWSKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV YKAKNNTVTP GGKPNKTRVI WGKVTRAHGN SGMVRAKFR SNLPAKAIGH RIRVMLYPSR I

UniProtKB: Large ribosomal subunit protein eL33

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分子 #31: 60S ribosomal protein L6

分子名称: 60S ribosomal protein L6 / タイプ: protein_or_peptide / ID: 31 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 32.810176 KDa
配列文字列: MAGEKVEKPD TKEKKPEAKK VDAGGKVKKG NLKAKKPKKG KPHCSRNPVL VRGIGRYSRS AMYSRKAMYK RKYSAAKSKV EKKKKEKVL ATVTKPVGGD KNGGTRVVKL RKMPRYYPTE DVPRKLLSHG KKPFSQHVRK LRASITPGTI LIILTGRHRG K RVVFLKQL ...文字列:
MAGEKVEKPD TKEKKPEAKK VDAGGKVKKG NLKAKKPKKG KPHCSRNPVL VRGIGRYSRS AMYSRKAMYK RKYSAAKSKV EKKKKEKVL ATVTKPVGGD KNGGTRVVKL RKMPRYYPTE DVPRKLLSHG KKPFSQHVRK LRASITPGTI LIILTGRHRG K RVVFLKQL ASGLLLVTGP LVLNRVPLRR THQKFVIATS TKIDISNVKI PKHLTDAYFK KKKLRKPRHQ EGEIFDTEKE KY EITEQRK IDQKAVDSQI LPKIKAIPQL QGYLRSVFAL TNGIYPHKLV F

UniProtKB: Large ribosomal subunit protein eL6

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分子 #32: 60S ribosomal protein L7

分子名称: 60S ribosomal protein L7 / タイプ: protein_or_peptide / ID: 32 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 29.290973 KDa
配列文字列: MEGVEEKKKE VPAVPETLKK KRRNFAELKI KRLRKKFAQK MLRKARRKLI YEKAKHYHKE YRQMYRTEIR MARMARKAGN FYVPAEPKL AFVIRIRGIN GVSPKVRKVL QLLRLRQIFN GTFVKLNKAS INMLRIVEPY IAWGYPNLKS VNELIYKRGY G KINKKRIA ...文字列:
MEGVEEKKKE VPAVPETLKK KRRNFAELKI KRLRKKFAQK MLRKARRKLI YEKAKHYHKE YRQMYRTEIR MARMARKAGN FYVPAEPKL AFVIRIRGIN GVSPKVRKVL QLLRLRQIFN GTFVKLNKAS INMLRIVEPY IAWGYPNLKS VNELIYKRGY G KINKKRIA LTDNALIARS LGKYGIICME DLIHEIYTVG KRFKEANNFL WPFKLSSPRG GMKKKTTHFV EGGDAGNRED QI NRLIRRM N

UniProtKB: Large ribosomal subunit protein uL30

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分子 #33: Protein LLP homolog

分子名称: Protein LLP homolog / タイプ: protein_or_peptide / ID: 33 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 15.268361 KDa
配列文字列:
MAKSLRSKWK RKMRAEKRKK NAPKEASRLK SILKLDGDVL MKDVQEIATV VVPKPKHCQE KMQCEVKDEK DDMKMETDIK RNKKTLLDQ HGQYPIWMNQ RQRKRLKAKR EKRKGKSKAK AVKVAKGLAW

UniProtKB: Protein LLP homolog

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分子 #34: 60S ribosomal protein L11

分子名称: 60S ribosomal protein L11 / タイプ: protein_or_peptide / ID: 34 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 20.288465 KDa
配列文字列:
MAQDQGEKEN PMRELRIRKL CLNICVGESG DRLTRAAKVL EQLTGQTPVF SKARYTVRSF GIRRNEKIAV HCTVRGAKAE EILEKGLKV REYELRKNNF SDTGNFGFGI QEHIDLGIKY DPSIGIYGLD FYVVLGRPGF SIADKKRRTG CIGAKHRISK E EAMRWFQQ KYDGIILPGK

UniProtKB: Large ribosomal subunit protein uL5

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分子 #35: 60S ribosomal protein L5

分子名称: 60S ribosomal protein L5 / タイプ: protein_or_peptide / ID: 35 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 34.426789 KDa
配列文字列: MGFVKVVKNK AYFKRYQVKF RRRREGKTDY YARKRLVIQD KNKYNTPKYR MIVRVTNRDI ICQIAYARIE GDMIVCAAYA HELPKYGVK VGLTNYAAAY CTGLLLARRL LNRFGMDKIY EGQVEVTGDE YNVESIDGQP GAFTCYLDAG LARTTTGNKV F GALKGAVD ...文字列:
MGFVKVVKNK AYFKRYQVKF RRRREGKTDY YARKRLVIQD KNKYNTPKYR MIVRVTNRDI ICQIAYARIE GDMIVCAAYA HELPKYGVK VGLTNYAAAY CTGLLLARRL LNRFGMDKIY EGQVEVTGDE YNVESIDGQP GAFTCYLDAG LARTTTGNKV F GALKGAVD GGLSIPHSTK RFPGYDSESK EFNAEVHRKH IMGQNVADYM RYLMEEDEDA YKKQFSQYIK NSVTPDMMEE MY KKAHAAI RENPVYEKKP KKEVKKKRWN RPKMSLAQKK DRVAQKKASF LRAQERAAES

UniProtKB: Large ribosomal subunit protein uL18

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分子 #36: Ribosome biogenesis protein NSA2 homolog

分子名称: Ribosome biogenesis protein NSA2 homolog / タイプ: protein_or_peptide / ID: 36 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 30.136703 KDa
配列文字列: MPQNEYIELH RKRYGYRLDY HEKKRKKESR EAHERSKKAK KMIGLKAKLY HKQRHAEKIQ MKKTIKMHEK RNTKQKNDEK TPQGAVPAY LLDREGQSRA KVLSNMIKQK RKEKAGKWEV PLPKVRAQGE TEVLKVIRTG KRKKKAWKRM VTKVCFVGDG F TRKPPKYE ...文字列:
MPQNEYIELH RKRYGYRLDY HEKKRKKESR EAHERSKKAK KMIGLKAKLY HKQRHAEKIQ MKKTIKMHEK RNTKQKNDEK TPQGAVPAY LLDREGQSRA KVLSNMIKQK RKEKAGKWEV PLPKVRAQGE TEVLKVIRTG KRKKKAWKRM VTKVCFVGDG F TRKPPKYE RFIRPMGLRF KKAHVTHPEL KATFCLPILG VKKNPSSPLY TTLGVITKGT VIEVNVSELG LVTQGGKVIW GK YAQVTNN PENDGCINAV LLV

UniProtKB: Ribosome biogenesis protein NSA2 homolog

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分子 #37: Notchless protein homolog 1

分子名称: Notchless protein homolog 1 / タイプ: protein_or_peptide / ID: 37 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 53.387141 KDa
配列文字列: MAAAVPDEAV ARDVQRLLVQ FQDEGGQLLG SPFDVPVDIT PDRLQLVCNA LLAQEDPLPL AFFVHDAEIV SSLGKTLESQ AVETEKVLD IIYQPQAIFR VRAVTRCTSS LEGHSEAVIS VAFSPTGKYL ASGSGDTTVR FWDLSTETPH FTCKGHRHWV L SISWSPDG ...文字列:
MAAAVPDEAV ARDVQRLLVQ FQDEGGQLLG SPFDVPVDIT PDRLQLVCNA LLAQEDPLPL AFFVHDAEIV SSLGKTLESQ AVETEKVLD IIYQPQAIFR VRAVTRCTSS LEGHSEAVIS VAFSPTGKYL ASGSGDTTVR FWDLSTETPH FTCKGHRHWV L SISWSPDG RKLASGCKNG QILLWDPSTG KQVGRTLAGH SKWITGLSWE PLHANPECRY VASSSKDGSV RIWDTTAGRC ER ILTGHTQ SVTCLRWGGD GLLYSASQDR TIKVWRAHDG VLCRTLQGHG HWVNTMALST DYALRTGAFE PAEASVNPQD LQG SLQELK ERALSRYNLV RGQGPERLVS GSDDFTLFLW SPAEDKKPLT RMTGHQALIN QVLFSPDSRI VASASFDKSI KLWD GRTGK YLASLRGHVA AVYQIAWSAD SRLLVSGSSD STLKVWDVKA QKLAMDLPGH ADEVYAVDWS PDGQRVASGG KDKCL RIWR R

UniProtKB: Notchless protein homolog 1

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分子 #38: Ribosome biogenesis regulatory protein homolog

分子名称: Ribosome biogenesis regulatory protein homolog / タイプ: protein_or_peptide / ID: 38 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 41.278523 KDa
配列文字列: MEGQSVEELL AKAEQDEAEK LQRITVHKEL ELQFDLGNLL ASDRNPPTGL RCAGPTPEAE LQALARDNTQ LLINQLWQLP TERVEEAIV ARLPEPTTRL PREKPLPRPR PLTRWQQFAR LKGIRPKKKT NLVWDEVSGQ WRRRWGYQRA RDDTKEWLIE V PGNADPLE ...文字列:
MEGQSVEELL AKAEQDEAEK LQRITVHKEL ELQFDLGNLL ASDRNPPTGL RCAGPTPEAE LQALARDNTQ LLINQLWQLP TERVEEAIV ARLPEPTTRL PREKPLPRPR PLTRWQQFAR LKGIRPKKKT NLVWDEVSGQ WRRRWGYQRA RDDTKEWLIE V PGNADPLE DQFAKRIQAK KERVAKNELN RLRNLARAHK MQLPSAAGLH PTGHQSKEEL GRAMQVAKVS TASVGRFQER LP KEKVPRG SGKKRKFQPL FGDFAAEKKN QLELLRVMNS KKPQLDVTRA TNKQMREEDQ EEAAKRRKMS QKGKRKGGRQ GPG GKRKGG PPSQGGKRKG GLGGKMNSGP PGLGGKRKGG QRPGGKRRK

UniProtKB: Ribosome biogenesis regulatory protein homolog

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分子 #39: Guanine nucleotide-binding protein-like 3

分子名称: Guanine nucleotide-binding protein-like 3 / タイプ: protein_or_peptide / ID: 39 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 62.098242 KDa
配列文字列: MKRPKLKKAS KRMTCHKRYK IQKKVREHHR KLRKEAKKRG HKKPRKDPGV PNSAPFKEAL LREAELRKQR LEELKQQQKL DRQKELEKK RKLETNPDIK PSNVEPMEKE FGLCKTENKA KSGKQNSKKL YCQELKKVIE ASDVVLEVLD ARDPLGCRCP Q VEEAIVQS ...文字列:
MKRPKLKKAS KRMTCHKRYK IQKKVREHHR KLRKEAKKRG HKKPRKDPGV PNSAPFKEAL LREAELRKQR LEELKQQQKL DRQKELEKK RKLETNPDIK PSNVEPMEKE FGLCKTENKA KSGKQNSKKL YCQELKKVIE ASDVVLEVLD ARDPLGCRCP Q VEEAIVQS GQKKLVLILN KSDLVPKENL ESWLNYLKKE LPTVVFRAST KPKDKGKITK RVKAKKNAAP FRSEVCFGKE GL WKLLGGF QETCSKAIRV GVIGFPNVGK SSIINSLKQE QMCNVGVSMG LTRSMQVVPL DKQITIIDSP SFIVSPLNSS SAL ALRSPA SIEVVKPMEA ASAILSQADA RQVVLKYTVP GYRNSLEFFT VLAQRRGMHQ KGGIPNVEGA AKLLWSEWTG ASLA YYCHP PTSWTPPPYF NESIVVDMKS GFNLEELEKN NAQSIRAIKG PHLANSILFQ SSGLTNGIIE EKDIHEELPK RKERK QEER EDDKDSDQET VDEEVDENSS GMFAAEETGE ALSEETTAGE QSTRSFILDK IIEEDDAYDF STDYV

UniProtKB: Guanine nucleotide-binding protein-like 3

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分子 #40: mRNA turnover protein 4 homolog

分子名称: mRNA turnover protein 4 homolog / タイプ: protein_or_peptide / ID: 40 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 27.602535 KDa
配列文字列: MPKSKRDKKV SLTKTAKKGL ELKQNLIEEL RKCVDTYKYL FIFSVANMRN SKLKDIRNAW KHSRMFFGKN KVMMVALGRS PSDEYKDNL HQVSKRLRGE VGLLFTNRTK EEVNEWFTKY TEMDYARAGN KAAFTVSLDP GPLEQFPHSM EPQLRQLGLP T ALKRGVVT ...文字列:
MPKSKRDKKV SLTKTAKKGL ELKQNLIEEL RKCVDTYKYL FIFSVANMRN SKLKDIRNAW KHSRMFFGKN KVMMVALGRS PSDEYKDNL HQVSKRLRGE VGLLFTNRTK EEVNEWFTKY TEMDYARAGN KAAFTVSLDP GPLEQFPHSM EPQLRQLGLP T ALKRGVVT LLSDYEVCKE GDVLTPEQAR VLKLFGYEMA EFKVTIKYMW DSQSGRFQQM GDDLPESASE STEESDSEDD D

UniProtKB: mRNA turnover protein 4 homolog

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分子 #41: G Protein Nucleolar 2

分子名称: G Protein Nucleolar 2 / タイプ: protein_or_peptide / ID: 41 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 83.796094 KDa
配列文字列: MVKPKYKGRS TINPSKASTN PDRVQGAGGQ NMRDRATIRR LNMYRQKERR NSRGKIIKPL QYQSTVASGT VARVEPNIKW FGNTRVIKQ SSLQKFQEEM DTVMKDPYKV VMKQSKLPMS LLHDRIRPHN LKVHILDTES FETTFGPKSQ RKRPNLFASD M QSLIENAE ...文字列:
MVKPKYKGRS TINPSKASTN PDRVQGAGGQ NMRDRATIRR LNMYRQKERR NSRGKIIKPL QYQSTVASGT VARVEPNIKW FGNTRVIKQ SSLQKFQEEM DTVMKDPYKV VMKQSKLPMS LLHDRIRPHN LKVHILDTES FETTFGPKSQ RKRPNLFASD M QSLIENAE MSTESYDQGK DRDLVTEDTG VRNEAQEEIY KKGQSKRIWG ELYKVIDSSD VVVQVLDARD PMGTRSPHIE TY LKKEKPW KHLIFVLNKC DLVPTWATKR WVAVLSQDYP TLAFHASLTN PFGKGAFIQL LRQFGKLHTD KKQISVGFIG YPN VGKSSV INTLRSKKVC NVAPIAGETK VWQYITLMRR IFLIDCPGVV YPSEDSETDI VLKGVVQVEK IKSPEDHIGA VLER AKPEY ISKTYKIDSW ENAEDFLEKL AFRTGKLLKG GEPDLQTVGK MVLNDWQRGR IPFFVKPPNA EPLVAPQLLP SSSLE VVPE AAQNNPGEEV TETAGEGSES IIKEETEENS HCDANTEMQQ ILTRVRQNFG KINVVPQFSG DDLVPVEVSD LEEELE SFS DEEEEEQEQQ RDDAEESSSE PEEENVGNDT KAVIKALDEK IAKYQKFLDK AKAKKFSAVR ISKGLSEKIF AKPEEQR KT LEEDVDDRAP SKKGKKRKAQ REEEQEHSNK APRALTSKER RRAVRQQRPK KVGVRYYETH NVKNRNRNKK KTNDSEGQ K HKRKKFRQKQ

UniProtKB: Nucleolar GTP-binding protein 2

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分子 #42: Coiled-coil domain-containing protein 86

分子名称: Coiled-coil domain-containing protein 86 / タイプ: protein_or_peptide / ID: 42 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 40.312742 KDa
配列文字列: MDTPLRRSRR LGGLRPESPE SLTSVSRTRR ALVEFESNPE ETREPGSPPS VQRAGLGSPE RPPKTSPGSP RLQQGAGLES PQGQPEPGA ASPQRQQDLH LESPQRQPEY SPESPRCQPK PSEEAPKCSQ DQGVLASELA QNKEELTPGA PQHQLPPVPG S PEPYPGQQ ...文字列:
MDTPLRRSRR LGGLRPESPE SLTSVSRTRR ALVEFESNPE ETREPGSPPS VQRAGLGSPE RPPKTSPGSP RLQQGAGLES PQGQPEPGA ASPQRQQDLH LESPQRQPEY SPESPRCQPK PSEEAPKCSQ DQGVLASELA QNKEELTPGA PQHQLPPVPG S PEPYPGQQ APGPEPSQPL LELTPRAPGS PRGQHEPSKP PPAGETVTGG FGAKKRKGSS SQAPASKKLN KEELPVIPKG KP KSGRVWK DRSKKRFSQM LQDKPLRTSW QRKMKERQER KLAKDFARHL EEEKERRRQE KKQRRAENLK RRLENERKAE VVQ VIRNPA KLKRAKKKQL RSIEKRDTLA LLQKQPPQQP AAKI

UniProtKB: Coiled-coil domain-containing protein 86

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分子 #45: 60S ribosomal protein L23a

分子名称: 60S ribosomal protein L23a / タイプ: protein_or_peptide / ID: 45 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 17.740193 KDa
配列文字列:
MAPKAKKEAP APPKAEAKAK ALKAKKAVLK GVHSHKKKKI RTSPTFRRPK TLRLRRQPKY PRKSAPRRNK LDHYAIIKFP LTTESAMKK IEDNNTLVFI VDVKANKHQI KQAVKKLYDI DVAKVNTLIR PDGEKKAYVR LAPDYDALDV ANKIGII

UniProtKB: Large ribosomal subunit protein uL23

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分子 #46: 60S ribosomal protein L22

分子名称: 60S ribosomal protein L22 / タイプ: protein_or_peptide / ID: 46 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 14.813015 KDa
配列文字列:
MAPVKKLVVK GGKKKKQVLK FTLDCTHPVE DGIMDAANFE QFLQERIKVN GKAGNLGGGV VTIERSKSKI TVTSEVPFSK RYLKYLTKK YLKKNNLRDW LRVVANSKES YELRYFQINQ DEEEEEDED

UniProtKB: Large ribosomal subunit protein eL22

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分子 #47: 60S ribosomal protein L31

分子名称: 60S ribosomal protein L31 / タイプ: protein_or_peptide / ID: 47 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 14.494938 KDa
配列文字列:
MAPAKKGGEK KKGRSAINEV VTREYTINIH KRIHGVGFKK RAPRALKEIR KFAMKEMGTP DVRIDTRLNK AVWAKGIRNV PYRIRVRLS RKRNEDEDSP NKLYTLVTYV PVTTFKNLQT VNVDEN

UniProtKB: Large ribosomal subunit protein eL31

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分子 #48: 60S ribosomal protein L32

分子名称: 60S ribosomal protein L32 / タイプ: protein_or_peptide / ID: 48 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 15.898932 KDa
配列文字列:
MAALRPLVKP KIVKKRTKKF IRHQSDRYVK IKRNWRKPRG IDNRVRRRFK GQILMPNIGY GSNKKTKHML PSGFRKFLVH NVKELEVLL MCNKSYCAEI AHNVSSKNRK AIVERAAQLA IRVTNPNARL RSEENE

UniProtKB: Large ribosomal subunit protein eL32

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分子 #49: 60S ribosomal protein L17

分子名称: 60S ribosomal protein L17 / タイプ: protein_or_peptide / ID: 49 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 21.44317 KDa
配列文字列:
MVRYSLDPEN PTKSCKSRGS NLRVHFKNTR ETAQAIKGMH IRKATKYLKD VTLQKQCVPF RRYNGGVGRC AQAKQWGWTQ GRWPKKSAE FLLHMLKNAE SNAELKGLDV DSLVIEHIQV NKAPKMRRRT YRAHGRINPY MSSPCHIEMI LTEKEQIVPK P EEEVAQKK KISQKKLKKQ KLMARE

UniProtKB: Large ribosomal subunit protein uL22

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分子 #50: 60S ribosomal protein L38

分子名称: 60S ribosomal protein L38 / タイプ: protein_or_peptide / ID: 50 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 8.238948 KDa
配列文字列:
MPRKIEEIKD FLLTARRKDA KSVKIKKNKD NVKFKVRCSR YLYTLVITDK EKAEKLKQSL PPGLAVKELK

UniProtKB: Large ribosomal subunit protein eL38

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分子 #52: Ribosome production factor 2 homolog

分子名称: Ribosome production factor 2 homolog / タイプ: protein_or_peptide / ID: 52 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 35.658078 KDa
配列文字列: MDTLDRVVKP KTKRAKRFLE KREPKLNENI KNAMLIKGGN ANATVTKVLK DVYALKKPYG VLYKKKNITR PFEDQTSLEF FSKKSDCSL FMFGSHNKKR PNNLVIGRMY DYHVLDMIEL GIENFVSLKD IKNSKCPEGT KPMLIFAGDD FDVTEDYRRL K SLLIDFFR ...文字列:
MDTLDRVVKP KTKRAKRFLE KREPKLNENI KNAMLIKGGN ANATVTKVLK DVYALKKPYG VLYKKKNITR PFEDQTSLEF FSKKSDCSL FMFGSHNKKR PNNLVIGRMY DYHVLDMIEL GIENFVSLKD IKNSKCPEGT KPMLIFAGDD FDVTEDYRRL K SLLIDFFR GPTVSNIRLA GLEYVLHFTA LNGKIYFRSY KLLLKKSGCR TPRIELEEMG PSLDLVLRRT HLASDDLYKL SM KMPKALK PKKKKNISHD TFGTTYGRIH MQKQDLSKLQ TRKMKGLKKR PAERITEDHE KKSKRIKKN

UniProtKB: Ribosome production factor 2 homolog

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分子 #53: pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

分子名称: pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 / タイプ: protein_or_peptide / ID: 53 / コピー数: 1 / 光学異性体: LEVO
EC番号: 転移酵素; 一炭素原子の基を移すもの; メチル基を移すもの
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 96.726875 KDa
配列文字列: MGKKGKVGKS RRDKFYHLAK ETGYRSRSAF KLIQLNRRFQ FLQKARALLD LCAAPGGWLQ VAAKFMPVSS LIVGVDLVPI KPLPNVVTL QQDITTERCR QALRKELKTW KVDVVLNDGA PNVGASWVHD AYSQAHLTLM ALRLACDFLA RGGSFITKVF R SRDYQPLL ...文字列:
MGKKGKVGKS RRDKFYHLAK ETGYRSRSAF KLIQLNRRFQ FLQKARALLD LCAAPGGWLQ VAAKFMPVSS LIVGVDLVPI KPLPNVVTL QQDITTERCR QALRKELKTW KVDVVLNDGA PNVGASWVHD AYSQAHLTLM ALRLACDFLA RGGSFITKVF R SRDYQPLL WIFQQLFRRV QATKPQASRH ESAEIFVVCQ GFLAPDKVDS KFFDPKFAFK EVEVQAKTVT ELVTKKKPKA EG YAEGDLT LYHRTSVTDF LRAANPVDFL SKASEIMVDD EELAQHPATT EDIRVCCQDI RVLGRKELRS LLNWRTKLRR YVA KKLKEQ AKALDISLSS GEEDEGDEED STAGTTKQPS KEEEEEEEEE QLNQTLAEMK AQEVAELKRK KKKLLREQRK QRER VELKM DLPGVSIADE GETGMFSLST IRGHQLLEEV TQGDMSAADT FLSDLPRDDI YVSDVEDDGD DTSLDSDLDP EELAG VRGH QGLRDQKRMR LTEVQDDKEE EEEENPLLVP LEEKAVLQEE QANLWFSKGS FAGIEDDADE ALEISQAQLL FENRRK GRQ QQQKQQLPQT PPSCLKTEIM SPLYQDEAPK GTEASSGTEA ATGLEGEEKD GISDSDSSTS SEEEESWEPL RGKKRSR GP KSDDDGFEIV PIEDPAKHRI LDPEGLALGA VIASSKKAKR DLIDNSFNRY TFNEDEGELP EWFVQEEKQH RIRQLPVG K KEVEHYRKRW REINARPIKK VAEAKARKKR RMLKRLEQTR KKAEAVVNTV DISEREKVAQ LRSLYKKAGL GKEKRHVTY VVAKKGVGRK VRRPAGVRGH FKVVDSRMKK DQRAQQRKEQ KKKHKRK

UniProtKB: pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

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分子 #43: 28S rRNA

分子名称: 28S rRNA / タイプ: rna / ID: 43 / コピー数: 1
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 1.6363565 MDa
配列文字列: CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAG AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGACA UGUGGCGUAC G GAAGACCC ...文字列:
CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAG AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGACA UGUGGCGUAC G GAAGACCC GCUCCCCGGC GCCGCUCGUG GGGGGCCCAA GUCCUUCUGA UCGAGGCCCA GCCCGUGGAC GGUGUGAG (B9B) CCGGUAGCGG CCCCCGGCGC GCCGGGCCCG GGUCUUCCCG GAGUCGGGUU GCUUGGGAAU GCAGCCCAAA GCGGG UGGU AAACUCCAUC UAAGGCUAAA UACCGGCACG AGACCGAUAG UCAACAAGUA CCGUAA(OMG)GGA AAGUUGAAAA GA ACUUUGA AG(A2M)GAGAGUU CAAGAGGGCG UGAAACCGUU AAGAGGUAAA CGGGUGGGGU CCGCGCAGUC CGCCCGGAG GAUUCAACCC GGCGGCGGGU CCGGCCGUGU CGGCGGCCCG GCGGAUCUUU CCCGCCCCCC GUUCCUCCCG ACCCCUCCAC CCGCCCUCC CUUCCCCCGC CGCCCCUCCU CCUCCUCCCC GGAGGGGGCG GGCUCCGGCG GGUGCGGGGG UGGGCGGGCG G GGCCGGGG GUGGGGUCGG CGGGGGACCG UCCCCCGACC GGCGACCGGC CGCCGCCGGG CGCAUUUCCA CCGCGGCGGU GC GCCGCGA CCGGCUCCGG GACGGCU(2MG)GG AAGGCCCGGC GGGGAAGGUG GCUCGGGGGG CCCCGUCCGU CCGUCCGUC CGUCCUCCUC CUCCCCCGUC UCCGCCCCCC GGCCCCGCGU CCUCCCUCGG GAGGGCGCGC GGGUCGGGGC GGCGGCGGCG GCGGCGGUG GCGGCGGCGG CGGCGGCGGC GGGACCGAAA CCCCCCCCGA GUGUUACAGC CCCCCCGGCA GCAGCACUCG C CGAAUCCC GGGGCCGAGG GAGCGAGACC CGUCGCCGC(2MG) CUCUCCCCCC UCCCGGCGCC CACCCCCGCG GGGAAUCC C CCGCGAGGGG GGUCUCCCCC GCGGGGGCGC GCCGGCGUCU CCUCGUGGGG GGGCCGGGCC ACCCCUCCCA CGGCGCGAC CGCUCUCCCA CCCCUCCUCC CCGCGCCCCC GCCCCGGCGA CGGGGGGGGU GCCGCGCGCG GGUCGGGGGG CGGGGCGGAC UGUCCCCAG UGCGCCCCGG GCGGGUCGCG CCGUCGGGCC CGGGGGAGGU UCUCUCGGGG CCACGCGCGC GUCCCCCGAA G AGGGGGAC GGCGGAGCGA GCGCACGGGG UCGGCGGCGA CGUCGGCUAC CCACCCGACC C(OMG)UCUUGAAA C(A2M)CG GACCA AGGAGUCUAA CACG(P4U)GCGCG AGUCGGGGGC UCGCACGAAA GCCGCCGUGG CGCAAUGAAG GUGAAGGCCG G CGCGCUCG CCGGCCGAGG UGGGAUCCCG AGGCCUCUCC AGUCCGCCGA GGG(B8Q)GCACCA CCGGCCCGUC UCGCCCGC C GCGCCGGGGA GGUGGAGCAC GAGCGCACGU GUUAG(2MG)ACCC (OMG)A(A2M)AGAUGGU GA(A2M)CUAUGCC UGG GCAGGG CGAAGCCAGA GGAAACUCUG GUG(B9B)AGGUCC GUAGCGGUCC UGACGUGCAA AUCG(7MG)UCGUC CGACCU GGG UAUAG(OMG)GGCG AAAGACUAAU CGAACCAUCU AGUAGCUGG(I4U) UCCCUCCGAA GUUUCCCUCA GGAUAGCUG GCGCUCUCGC AGACCCGACG CACCCCCGCC ACGCAGUUUU AUCCGGUAAA GCGAAUGAUU AGAGGUCUUG GGGCCGAAAC GAUCUCAAC CUAUUCUCAA ACUUUAAAU(E7G) GGUAAGAAGC CCGGCUCGCU GGCGUGGAGC CGGGCGUGGA AUGCGAG UG CCUAGUGGGC CACUUUUGGU AAGC(A2M)GAACU GGCGCU(OMG)CGG GAUGAACCGA ACGCCGGGUU AA(P7G)GCG CCC GAUGCCGACG CUCAUCAGAC CCCAGAAAAG GUGUUGGUUG AUAUAGACAG CAGGACGGUG GCCAUGGAAG UCGGAAU CC GCUAAGGAGU GUGUAACAAC UCACCUGCCG AAUCAACUAG CCCUGAAAAU GGAUG(OMG)CGCU GGAGCGUCGG GCCC AUACC CGGCCGUCGC CGGCAGUCGA GAGUGGACGG GAGCGGCGGC GGCGGCGCGC GCGCGCGCGC GUGUGGUGUG CGUCG GAGG GCGGCGGCGG CGGCGGCGGC GGGGGUGUGG GGUCCUUCCC CCGCCCCCCC CCCCACGCCU CCUCCCCUCC UCCCGC CCA CGCCCCGCUC CCCGCCCCCG GAGCCCCGCG GACGCUACGC CGCGACGAGU AGGAGGGCCG CUGCG(E7G)UGAG CCU UGAAGC CUAGGGCGCG GGCCCGGGUG GAGCCGCCGC AGGUGCAGAU CUUGGUGGUA GU(A2M)(OMG)(OMC)AAAUA UU CAAACGA (B8W)AACUUUGAA GGCCGAAGUG G(A2M)GAAGGGUU CCAUGUGAAC AG(OMC)A(OMG)UUGAA CAUGGGU CA GUCGGUCCUG AGAGAUGGGC GAGCGCCGUU CCGAAGGGAC GGGCGAUGGC CUCCGUUGCC CUCGGCCGAU CGAAAGGG A GUCG(7MG)GUUCA GAUCCCCGAA UCCGGAGUGG CGGAGAUGGG CGCCGCGAGG CGUCCAGUGC GGUAACGCGA CCGAU CCCG GAGAAGCCGG CGGGAGCCCC GGGGAGAGUU CUCUUUUCUU UGUGAAGGGC AGGGCGCCCU GGAAUGGGUU CGCCCC GAG AGAGGGGCCC GUGCCUUGGA AAGCGUCGCG GUUCCGGCGG CGUCCGGUGA GCUCUCGCUG GCCCUUGAAA AUCCGGG G(B9B) AGAGGGUGUA AAUCUCGC(OMG)C CGGGCCGUAC C(B9H)AUAUCCGC AGCAGGUCU(OMC) CAAGGUGAAC AG CCUCUGG CAUGUUGGAA CAAUGUAGGU AAGGGAAGUC GGCAAGC(OMC)GG AUCCGUAACU UCGGGAUAAG GAUUGGCUC UAAGGGCUGG GUCGGUCGGG CUGGGGCGCG AAGCGGGGCU GGGCGCGCGC CGCGGCUGGA CGAGGCGCCG CCGCCCCCCC CACGCCCGG GGCACCCCCC UCGCGGCCCU CCCCCGCCCC ACCCCGCGCG CGCCGCUCGC UCCCUCCCCG CCCCGCGCCC U CUCUCUCU CUCUCUCCCC CGCUCCCCGU CCUCCCCCCU CCCCGGGGGA GCGCCGCGUG GGGGCGGCGG CGGGGGGAGA AG GGUCGGG GCGGCAGGGG CCGGCGGCGG CCCGCCGCGG GGCCCCGGCG GCGGGGGCAC GGUCCCCCGC GAGGGGGGCC CGG GCACCC GGGGGGCCGG CGGCGGCGGC GACUCUGGAC GCGAGCCGGG CCCUUCCCGU GGAUCGCCCC AGCUGCGGCG GGCG UCGCG GCCGCCCCCG GGGAGCCCGG CGGGCGCCGG CGCGCCCCCC CCCCCACCCC ACGUCUCGUC GCGCGCGCGU CCGCU GGGG GCGGGGAGCG GUCGGGCGGC GGCGGUCGGC GGGCGGCGGG GCGGGGCGGU UCGUCCCCCC GCCCUACCCC CCCGGC CCC GUCCGCCCCC CGUUCCCCCC UCCUCCUCGG CGCGCGGCGG CGGCGGCGGC AGGCGGCGGA GGGGCCGCGG GCCGGUC CC CCCCGCCGGG UCCGCCCCCG GGGCCGCGGU UCCGCGCGGC GCCUCGCCUC GGCCGGCGCC UAGCAGCCGA CUUAGAAC U GGUGCGGACC AGGGGAAUCC GACUGUUUAA UUAAAACAAA GCAUCGCGAA GGCCCGCGGC GGGUGUUGAC GCGAUGUGA UUUCUGCC(OMC)A GUGCUCUGAA UGUCAAAGUG AAGAAAUUCA AUGAAGCGCG GGUAAACGGC GGGAGUAACU AUGACU CUC UUAAGGUAGC CAAAUGCCUC GUCAUCUAAU UAGUGACGCG CAUGAAUGGA UGA(A2M)CGAGAU UCCCACUGUC CCU ACCUAC UAUCCAGCGA AACCAC(A2M)G(OMC)C AAGGGAACG(P7G) GCUUGG(OMC)GGA AUCAGC(B8K)G(BGH)G AAAGAAGA(OMC) CCUGUUGAGC UUGACUCUAG UCUGGCACGG UGAAGAGACA UGAGAGGUGU AGAAUAAGUG GGAGGCC CC CGGCGCCCCC CCGGUGUCCC CGCGAGGGGC CCGGGGCGGG GUCCGCCGGC CCUGCGGGCC GCCGGUGAAA UACCACUA C UCUGAUCGUU UUUUCACUGA CCCGG(5MU)GAGG CGGGGGGGCG AGCCCCGAGG GGCUCUCGCU UCUGGCGCCA AGCGC CCGG CCGCGCGCCG GCCGGGCGCG ACCCGCUCCG GGGACAGUGC CAGGUGGG(B8W)A GUUUGACUGG GGCGGUACAC CU GUCAAAC GGUAACGCAG GUGUCCUAAG GCGAGCUCAG GGAGGACAGA AACCUCCCGU GGAGCAGAAG GGCAAAAGCU CGC UUGAUC UUGAUUUUCA GUACGAAUAC AGACCGUGAA AGCGGGGCCU CACGAUCCUU CUGACCUUUU GGGUUUUAAG CAGG AGGUG UCAGAAAAGU UACCACAGGG AUAACUGGCU UGUGGCGGCC A(1MA)GCGUUCAU AGCGACGUCG CUUUUUGAUC C UUCGAUGU CGGCUCUUCC UAUCAUUGU(B8W) AAGCAGAAUU (B8T)ACCAAGCGU U(OMG)GAUUGUUC ACCCACUAAU AGGGAACGU G(A2M)GCUGGGUU UAGACCGUCG UGAGACAG(7MG)U UAGUUUUACC CU(M7A)CUGAUGA UGUGUUGUU GCCAUGGUAA UCCUGC(UR3)CAG UACGAGAGGA ACCGCAGGU(OMU) CA(OMG)ACAUUUG GUGUAU(OMG)UGC UUGG CUGAG GAGCCAAUGG GGCGAAGCUA C(B8T)AUCUGUGG GAUUAUGACU (B8K)AACGCCUCU AAGUCAGAAU CCCGCCC AG GCGGAACGAU ACGGCAGCGC CGCGGAGCCU CGGUUGGCCU CGGAUAGCCG GUCCCCCGGG CCGCCCCCCC CCUCCACG C GCCCCGCGCG CGCGGGAGGG CGCGUGCCCC GCCGCGCGCC GGGACCGGGG UCCGGU(OMG)C(2MG)G AGUGCCCUUC G UCCUGGGA AACGGGGCGC GGCCGGAGAG GCGGCCGCCC CCUCGCCCGU CACGCACCGC ACGUUCGUGG GGAACCUGGC GC UAAACCA UUCGUAGACG ACCUGCUUCU GGGUCGGGGU UUCGUACGUA GCAGAGCAGC UCCCUCGCUG CGAUCUAUUG AAA GUCAGC CCUCGACACA AGGGUUUGUC

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分子 #44: 5.8S rRMA

分子名称: 5.8S rRMA / タイプ: rna / ID: 44 / コピー数: 1
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 50.157676 KDa
配列文字列:
CGACUCUUAG CGG(OMU)GGAUCA CUCGGCUCGU GCGUCGAUGA AGAACGCAGC UAGCUGCGAG AAUUAAUGUG AAUUGC AGG ACACAUUGAU CAUCGACACU UCGAACGCAC UUGCGGCCCC GGGUUCCUCC CGGGGCUACG CCUGUCUGAG CGUCGCU

GENBANK: GENBANK: KY962518.1

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分子 #51: 5S RNA

分子名称: 5S RNA / タイプ: rna / ID: 51 / コピー数: 1
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 38.691914 KDa
配列文字列:
GUCUACGGCC AUACCACCCU GAACGCGCCC GAUCUCGUCU GAUCUCGGAA GCUAAGCAGG GUCGGGCCUG GUUAGUACUU GGAUGGGAG ACCGCCUGGG AAUACCGGGU GCUGUAGGCU U

GENBANK: GENBANK: NR_023363.1

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分子 #54: GUANOSINE-5'-TRIPHOSPHATE

分子名称: GUANOSINE-5'-TRIPHOSPHATE / タイプ: ligand / ID: 54 / コピー数: 1 / 式: GTP
分子量理論値: 523.18 Da
Chemical component information

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, エネルギー貯蔵分子*YM

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分子 #55: MAGNESIUM ION

分子名称: MAGNESIUM ION / タイプ: ligand / ID: 55 / コピー数: 1 / 式: MG
分子量理論値: 24.305 Da

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実験情報

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構造解析

手法クライオ電子顕微鏡法
解析単粒子再構成法
試料の集合状態particle

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試料調製

緩衝液pH: 7.5
凍結凍結剤: ETHANE

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電子顕微鏡法

顕微鏡FEI TITAN KRIOS
撮影フィルム・検出器のモデル: GATAN K2 QUANTUM (4k x 4k)
平均電子線量: 1.8 e/Å2
電子線加速電圧: 300 kV / 電子線源: FIELD EMISSION GUN
電子光学系照射モード: OTHER / 撮影モード: DIFFRACTION / 最大 デフォーカス（公称値）: 1.8 µm / 最小 デフォーカス（公称値）: 1.2 µm
実験機器
モデル: Titan Krios / 画像提供: FEI Company

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画像解析

CTF補正タイプ: PHASE FLIPPING AND AMPLITUDE CORRECTION
初期モデルモデルのタイプ: INSILICO MODEL
最終 再構成解像度のタイプ: BY AUTHOR / 解像度: 3.3 Å / 解像度の算出法: FSC 0.143 CUT-OFF / 使用した粒子像数: 30311
初期 角度割当タイプ: MAXIMUM LIKELIHOOD
最終 角度割当タイプ: MAXIMUM LIKELIHOOD

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

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