登録情報 データベース : EMDB / ID : EMD-22449 構造の表示 ダウンロードとリンクタイトル Plant mitochondrial supercomplex III2+IV from Vigna radiata マップデータPlant mitochondrial supercomplex III2 IV from Vigna radiata. 詳細 試料複合体 : Mitochondrial Respiratory Complex III2 詳細機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
protein processing involved in protein targeting to mitochondrion / respiratory chain complex IV / mitochondrial respiratory chain complex IV / mitochondrial respiratory chain complex III / mitochondrial respirasome / quinol-cytochrome-c reductase / ubiquinol-cytochrome-c reductase activity / mitochondrial electron transport, cytochrome c to oxygen / cytochrome-c oxidase activity / mitochondrial electron transport, ubiquinol to cytochrome c ... protein processing involved in protein targeting to mitochondrion / respiratory chain complex IV / mitochondrial respiratory chain complex IV / mitochondrial respiratory chain complex III / mitochondrial respirasome / quinol-cytochrome-c reductase / ubiquinol-cytochrome-c reductase activity / mitochondrial electron transport, cytochrome c to oxygen / cytochrome-c oxidase activity / mitochondrial electron transport, ubiquinol to cytochrome c / respirasome / metalloendopeptidase activity / 2 iron, 2 sulfur cluster binding / mitochondrial inner membrane / membrane => GO:0016020 / electron transfer activity / copper ion binding / heme binding / mitochondrion / proteolysis / metal ion binding 類似検索 - 分子機能 Cytochrome c oxidase subunit 5c / Protein of unknown function DUF1138 / Protein of unknown function (DUF1138) / Predicted cytochrome c oxidase subunit VII / Cytochrome b-c1 complex subunit 8, plants / Cytochrome b-c1 complex subunit 8 / Cytochrome c oxidase, subunit VIa / Cytochrome b-c1 complex, subunit 6 / Cytochrome c oxidase, subunit VIa superfamily / Cytochrome c oxidase subunit VIa ... Cytochrome c oxidase subunit 5c / Protein of unknown function DUF1138 / Protein of unknown function (DUF1138) / Predicted cytochrome c oxidase subunit VII / Cytochrome b-c1 complex subunit 8, plants / Cytochrome b-c1 complex subunit 8 / Cytochrome c oxidase, subunit VIa / Cytochrome b-c1 complex, subunit 6 / Cytochrome c oxidase, subunit VIa superfamily / Cytochrome c oxidase subunit VIa / Cytochrome c oxidase, subunit VIb / Cytochrome c oxidase, subunit VIb superfamily / Cytochrome oxidase c subunit VIb / Cytochrome c oxidase subunit VII / Cytochrome c oxidase subunit VII / Cytochrome c oxidase subunit 2, C-terminal / Cytochrome c oxidase, subunit Vb / Cytochrome c oxidase, subunit Vb superfamily / Cytochrome c oxidase subunit Vb / Cytochrome c oxidase subunit Vb, zinc binding domain profile. / Cytochrome c oxidase, subunit II / Cytochrome C oxidase subunit II, transmembrane domain / Cytochrome b-c1 complex subunit 7 / Cytochrome b-c1 complex subunit 7 superfamily / Ubiquinol-cytochrome C reductase complex 14kD subunit / Cytochrome b-c1 complex subunit 9 / Cytochrome b-c1 complex subunit 8 superfamily / Cytochrome b-c1 complex subunit 9 superfamily / Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like / Cytochrome b-c1 complex subunit Rieske, transmembrane domain / Ubiquinol cytochrome reductase transmembrane region / Ubiquinol-cytochrome C reductase hinge domain / Ubiquinol-cytochrome C reductase hinge domain superfamily / Ubiquinol-cytochrome C reductase hinge protein / Cytochrome C oxidase subunit II, transmembrane domain / Cytochrome c1, transmembrane anchor, C-terminal / Cytochrome oxidase subunit II transmembrane region profile. / Cytochrome c/quinol oxidase subunit II / Ubiquinol-cytochrome c reductase, iron-sulphur subunit / Cytochrome c1 / Cytochrome C1 family / Copper centre Cu(A) / CO II and nitrous oxide reductase dinuclear copper centers signature. / Cytochrome C oxidase subunit II, transmembrane domain superfamily / Peptidase M16, zinc-binding site / Insulinase family, zinc-binding region signature. / Rieske iron-sulphur protein, C-terminal / Cytochrome C oxidase subunit II, periplasmic domain / Cytochrome c oxidase subunit II-like C-terminal / Cytochrome oxidase subunit II copper A binding domain profile. / Rieske iron-sulphur protein / Peptidase M16, C-terminal / Peptidase M16 inactive domain / Peptidase M16, N-terminal / Insulinase (Peptidase family M16) / Metalloenzyme, LuxS/M16 peptidase-like / Rieske [2Fe-2S] iron-sulphur domain / Rieske [2Fe-2S] domain / Rieske [2Fe-2S] iron-sulfur domain profile. / Rieske [2Fe-2S] iron-sulphur domain superfamily / Cytochrome c family profile. / Cytochrome c-like domain / Cytochrome c-like domain superfamily / Cupredoxin 類似検索 - ドメイン・相同性 Cytochrome b-c1 complex subunit Rieske, mitochondrial / uncharacterized protein LOC106757297 / Complex III subunit 9 / uncharacterized protein LOC106759053 / Probable mitochondrial-processing peptidase subunit beta, mitochondrial isoform X1 / Cytochrome c oxidase subunit 2 / cytochrome c oxidase subunit 5b-2, mitochondrial / Cytochrome b-c1 complex subunit 7 / Cytochrome b-c1 complex subunit 8 / cytochrome c oxidase subunit 6a, mitochondrial ... Cytochrome b-c1 complex subunit Rieske, mitochondrial / uncharacterized protein LOC106757297 / Complex III subunit 9 / uncharacterized protein LOC106759053 / Probable mitochondrial-processing peptidase subunit beta, mitochondrial isoform X1 / Cytochrome c oxidase subunit 2 / cytochrome c oxidase subunit 5b-2, mitochondrial / Cytochrome b-c1 complex subunit 7 / Cytochrome b-c1 complex subunit 8 / cytochrome c oxidase subunit 6a, mitochondrial / Cytochrome c oxidase subunit 5C / uncharacterized protein LOC106772338 / Mitochondrial-processing peptidase subunit alpha / Cytochrome b-c1 complex subunit 6 / cytochrome c oxidase subunit 6b-1 / Cytochrome c1-2, heme protein, mitochondrial 類似検索 - 構成要素生物種 Vigna radiata (リョクトウ)手法 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度 : 3.8 Å 詳細 データ登録者Maldonado M / Letts JA 引用ジャーナル : Elife / 年 : 2021タイトル : Atomic structures of respiratory complex III, complex IV, and supercomplex III-IV from vascular plants.著者 : Maria Maldonado / Fei Guo / James A Letts / 要旨 : Mitochondrial complex III (CIII) and complex IV (CIV), which can associate into a higher-order supercomplex (SC III+IV), play key roles in respiration. However, structures of these plant complexes ... Mitochondrial complex III (CIII) and complex IV (CIV), which can associate into a higher-order supercomplex (SC III+IV), play key roles in respiration. However, structures of these plant complexes remain unknown. We present atomic models of CIII, CIV, and SC III+IV from determined by single-particle cryoEM. The structures reveal plant-specific differences in the MPP domain of CIII and define the subunit composition of CIV. Conformational heterogeneity analysis of CIII revealed long-range, coordinated movements across the complex, as well as the motion of CIII's iron-sulfur head domain. The CIV structure suggests that, in plants, proton translocation does not occur via the H channel. The supercomplex interface differs significantly from that in yeast and bacteria in its interacting subunits, angle of approach and limited interactions in the mitochondrial matrix. These structures challenge long-standing assumptions about the plant complexes and generate new mechanistic hypotheses. 履歴 登録 2020年8月12日 - ヘッダ(付随情報) 公開 2021年1月20日 - マップ公開 2021年1月20日 - 更新 2021年2月3日 - 現状 2021年2月3日 処理サイト : RCSB / 状態 : 公開
すべて表示 表示を減らす