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- EMDB-18399: SARS-CoV-2 Spike in complex with the neutralizing antibody Cv2.3194 -
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Open data
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Basic information
Entry | ![]() | |||||||||
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Title | SARS-CoV-2 Spike in complex with the neutralizing antibody Cv2.3194 | |||||||||
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![]() | Coronavirus Neutralizing Antibody / VIRAL PROTEIN | |||||||||
Biological species | ![]() ![]() | |||||||||
Method | single particle reconstruction / cryo EM / Resolution: 3.2 Å | |||||||||
![]() | Fernandez I / Rey FA / Guardado-Calvo P | |||||||||
Funding support | 1 items
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![]() | ![]() Title: A broadly neutralizing antibody against SARS-CoV-2 Omicron variants Authors: Planchais C / Fernandez I / Rey FA / Mouquet H | |||||||||
History |
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Structure visualization
Supplemental images |
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Downloads & links
-EMDB archive
Map data | ![]() | 307 MB | ![]() | |
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Header (meta data) | ![]() ![]() | 10.8 KB 10.8 KB | Display Display | ![]() |
Images | ![]() | 64.1 KB | ||
Filedesc metadata | ![]() | 3.6 KB | ||
Others | ![]() ![]() | 301.2 MB 301.1 MB | ||
Archive directory | ![]() ![]() | HTTPS FTP |
-Validation report
Summary document | ![]() | 1.2 MB | Display | ![]() |
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Full document | ![]() | 1.2 MB | Display | |
Data in XML | ![]() | 17 KB | Display | |
Data in CIF | ![]() | 20.2 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
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Links
EMDB pages | ![]() ![]() |
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Map
File | ![]() | ||||||||||||||||||||
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Voxel size | X=Y=Z: 0.86 Å | ||||||||||||||||||||
Density |
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Symmetry | Space group: 1 | ||||||||||||||||||||
Details | EMDB XML:
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-Supplemental data
-Half map: #2
File | emd_18399_half_map_1.map | ||||||||||||
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Projections & Slices |
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Density Histograms |
-Half map: #1
File | emd_18399_half_map_2.map | ||||||||||||
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Projections & Slices |
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Density Histograms |
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Sample components
-Entire : Complex formed by the SARS-CoV-2 Spike and a Fab from the antibod...
Entire | Name: Complex formed by the SARS-CoV-2 Spike and a Fab from the antibody Cv2.3194 |
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Components |
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-Supramolecule #1: Complex formed by the SARS-CoV-2 Spike and a Fab from the antibod...
Supramolecule | Name: Complex formed by the SARS-CoV-2 Spike and a Fab from the antibody Cv2.3194 type: complex / ID: 1 / Parent: 0 |
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Source (natural) | Organism: ![]() ![]() |
-Experimental details
-Structure determination
Method | cryo EM |
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![]() | single particle reconstruction |
Aggregation state | particle |
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Sample preparation
Buffer | pH: 8 |
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Vitrification | Cryogen name: ETHANE / Instrument: FEI VITROBOT MARK IV |
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Electron microscopy
Microscope | FEI TITAN |
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Image recording | Film or detector model: GATAN K3 (6k x 4k) / Average electron dose: 50.0 e/Å2 |
Electron beam | Acceleration voltage: 300 kV / Electron source: ![]() |
Electron optics | Illumination mode: FLOOD BEAM / Imaging mode: BRIGHT FIELD / Nominal defocus max: 3.0 µm / Nominal defocus min: 1.0 µm |
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Image processing
Startup model | Type of model: OTHER / Details: Ab-initio model |
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Final reconstruction | Resolution.type: BY AUTHOR / Resolution: 3.2 Å / Resolution method: FSC 0.143 CUT-OFF / Number images used: 365979 |
Initial angle assignment | Type: NOT APPLICABLE |
Final angle assignment | Type: NOT APPLICABLE |