登録情報 データベース : EMDB / ID : EMD-15865 ダウンロードとリンクタイトル Cryo-EM structure of NADH:ubiquinone oxidoreductase (complex-I) from respiratory supercomplex of Tetrahymena thermophila マップデータSharpened mask refined map 詳細 試料複合体 : NADH:ubiquinone oxidoreductase complex (complex-I) from respiratory supercomplex of Tetrahymena thermophilaリガンド : x 13種 詳細機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
NADH:ユビキノン還元酵素 (水素イオン輸送型) / lipid-A-disaccharide synthase / lipid-A-disaccharide synthase activity / medium-chain fatty acid-CoA ligase activity / P450-containing electron transport chain / ubiquinone-6 biosynthetic process / oxidoreductase activity, acting on NAD(P)H / lipid A biosynthetic process / NADH dehydrogenase activity / NADH:ユビキノン還元酵素 (水素イオン輸送型) ... NADH:ユビキノン還元酵素 (水素イオン輸送型) / lipid-A-disaccharide synthase / lipid-A-disaccharide synthase activity / medium-chain fatty acid-CoA ligase activity / P450-containing electron transport chain / ubiquinone-6 biosynthetic process / oxidoreductase activity, acting on NAD(P)H / lipid A biosynthetic process / NADH dehydrogenase activity / NADH:ユビキノン還元酵素 (水素イオン輸送型) / mitochondrial respiratory chain complex I / ubiquinone binding / mitochondrial electron transport, NADH to ubiquinone / respirasome / chloroplast thylakoid membrane / mitochondrial respiratory chain complex I assembly / acyl binding / NADH dehydrogenase (ubiquinone) activity / acyl carrier activity / electron transport coupled proton transport / quinone binding / ATP synthesis coupled electron transport / 細胞呼吸 / respiratory electron transport chain / mitochondrion organization / 葉緑体 / fatty acid metabolic process / 電子伝達系 / ミトコンドリア / phospholipid binding / 2 iron, 2 sulfur cluster binding / NAD binding / FMN binding / 4 iron, 4 sulfur cluster binding / response to oxidative stress / oxidoreductase activity / リボソーム / protein-containing complex binding / negative regulation of apoptotic process / protein kinase binding / ミトコンドリア / 生体膜 / metal ion binding / 細胞質基質 類似検索 - 分子機能 Glycosyl transferase, family 19 / Lipid-A-disaccharide synthetase / : / Dynactin subunit 5 / NADH-ubiquinone oxidoreductase, 21kDa subunit, N-terminal / NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit / Adrenodoxin / DnaJ domain / DnaJ molecular chaperone homology domain / dnaJ domain profile. ... Glycosyl transferase, family 19 / Lipid-A-disaccharide synthetase / : / Dynactin subunit 5 / NADH-ubiquinone oxidoreductase, 21kDa subunit, N-terminal / NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit / Adrenodoxin / DnaJ domain / DnaJ molecular chaperone homology domain / dnaJ domain profile. / Chaperone J-domain superfamily / DnaJ domain / Hexapeptide repeat / Soluble ligand binding domain / SLBB domain / 2Fe-2S iron-sulfur cluster binding domain / Bacterial transferase hexapeptide (six repeats) / Zinc finger, CHCC-type / Zinc-finger domain / NADH dehydrogenase ubiquinone Fe-S protein 4-like superfamily / NADH dehydrogenase ubiquinone Fe-S protein 4 / NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2 / NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial / NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 / NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 / ETC complex I subunit conserved region / NADH ubiquinone oxidoreductase subunit NDUFA12 / NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6 / チオレドキシン / NADH-quinone oxidoreductase, chain G, C-terminal / NADH-ubiquinone oxidoreductase subunit G, C-terminal / NADH-ubiquinone oxidoreductase, 20 Kd subunit / NADH-quinone oxidoreductase, chain I / Trimeric LpxA-like superfamily / NAD(P)H-quinone oxidoreductase subunit D/H / NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site / Respiratory chain NADH dehydrogenase 49 Kd subunit signature. / NADH-quinone oxidoreductase, subunit D / Respiratory-chain NADH dehydrogenase, 49 Kd subunit / NADH:ubiquinone oxidoreductase, subunit G / Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. / Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. / NADH ubiquinone oxidoreductase, F subunit / NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site / Respiratory chain NADH dehydrogenase 30 Kd subunit signature. / AMP-dependent synthetase/ligase / AMP-binding enzyme / 2Fe-2S iron-sulfur cluster binding domain / Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. / NADH-quinone oxidoreductase, chain 5-like / NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site / NADH:ubiquinone oxidoreductase, 30kDa subunit / NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily / Respiratory-chain NADH dehydrogenase, 30 Kd subunit / NADH-ubiquinone oxidoreductase-G iron-sulfur binding region / NADH-ubiquinone oxidoreductase-G iron-sulfur binding region / NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 / NADH:ubiquinone oxidoreductase, subunit 3 superfamily / NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 / NADH:ubiquinone oxidoreductase, subunit 1, conserved site / Respiratory-chain NADH dehydrogenase subunit 1 signature 1. / Respiratory-chain NADH dehydrogenase subunit 1 signature 2. / NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H / NADHデヒドロゲナーゼ / NuoE domain / NADH:ubiquinone oxidoreductase / NADH-quinone oxidoreductase subunit E-like / Thioredoxin-like [2Fe-2S] ferredoxin / NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit / Proton-conducting membrane transporter / NADH-quinone oxidoreductase subunit E, N-terminal / NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site / Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. / NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding / His(Cys)3-ligated-type [4Fe-4S] domain profile. / NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain / NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain / NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily / NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily / Respiratory-chain NADH dehydrogenase 51 Kd subunit / NADH-ubiquinone oxidoreductase-F iron-sulfur binding region / NADH-ubiquinone oxidoreductase-F iron-sulfur binding region / Coiled coil-helix-coiled coil-helix (CHCH) domain profile. / Molybdopterin oxidoreductase, 4Fe-4S domain / Prokaryotic molybdopterin oxidoreductases 4Fe-4S domain profile. / NAD-dependent epimerase/dehydratase / NAD dependent epimerase/dehydratase family / NADH:ubiquinone oxidoreductase-like, 20kDa subunit / NADH ubiquinone oxidoreductase, 20 Kd subunit / Molybdopterin oxidoreductase / Molybdopterin oxidoreductase / [NiFe]-hydrogenase, large subunit / Ribosomal protein/NADH dehydrogenase domain / Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain / Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain / Acyl carrier protein (ACP) / Beta-grasp domain superfamily / 4Fe-4S dicluster domain / 2Fe-2S ferredoxin-type iron-sulfur binding domain profile. / 2Fe-2S ferredoxin-type iron-sulfur binding domain 類似検索 - ドメイン・相同性 Transmembrane protein, putative / NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 / NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit / Transmembrane protein, putative / Uncharacterized protein / Uncharacterized protein / 膜貫通型タンパク質 / NADH dehydrogenase, putative / Gamma-carbonic anhydrase / 膜貫通型タンパク質 ... Transmembrane protein, putative / NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 / NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit / Transmembrane protein, putative / Uncharacterized protein / Uncharacterized protein / 膜貫通型タンパク質 / NADH dehydrogenase, putative / Gamma-carbonic anhydrase / 膜貫通型タンパク質 / Transcription factor apfi protein, putative / Transmembrane protein, putative / Ribosomal protein L51/S25/CI-B8 domain protein / 膜貫通型タンパク質 / Acyl carrier protein / NADH-ubiquinone oxidoreductase 1, chain, putative / NADH-ubiquinone oxidoreductase 24 kDa subunit / 膜貫通型タンパク質 / Transmembrane protein, putative / 膜貫通型タンパク質 / Uncharacterized protein / Transmembrane protein, putative / Uncharacterized protein / Zinc-finger protein / NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial / NAD-dependent epimerase/dehydratase family protein / 膜貫通型タンパク質 / チオレドキシン / Transmembrane protein, putative / DnaJ domain protein / lipid-A-disaccharide synthase / 膜貫通型タンパク質 / Transmembrane protein, putative / 膜貫通型タンパク質 / Transmembrane protein, putative / 2 iron, 2 sulfur cluster-binding protein / 膜貫通型タンパク質 / Acyl carrier protein / Gamma-carbonic anhydrase / Transmembrane protein, putative / 膜貫通型タンパク質 / Uncharacterized protein / Uncharacterized protein / NADH-ubiquinone oxidoreductase 75 kDa subunit / Uncharacterized protein / NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial / Uncharacterized protein / ETC complex I subunit motif protein / Transmembrane protein, putative / Transmembrane protein, putative / Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II / NADH-ubiquinone oxidoreductase chain 4 / Ymf62 / NADH-ubiquinone oxidoreductase chain 1 / NADH dehydrogenase subunit 5 / NADH dehydrogenase subunit 9 / Ymf58 / NADH-ubiquinone oxidoreductase chain 3 / Ymf65 / NADH dehydrogenase subunit 7 / NADH dehydrogenase subunit 2 / NADH dehydrogenase subunit 10 / Ymf57 / GRAM domain protein 類似検索 - 構成要素生物種 Tetrahymena thermophila (真核生物) / Tetrahymena thermophila SB210 (真核生物)手法 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度 : 2.8 Å 詳細 データ登録者Muhleip A / Kock Flygaard R / Amunts A 資金援助 スウェーデン, European Union, 4件 詳細 詳細を隠すOrganization Grant number 国 The Swedish Foundation for Strategic Research FFL15:0325 スウェーデン Cancerfonden 2017/1041 スウェーデン European Research Council (ERC) ERC-2018-StG-805230 European Union Knut and Alice Wallenberg Foundation 2018.0080 スウェーデン
引用 残り1件を表示 表示を減らす履歴 登録 2022年9月27日 - ヘッダ(付随情報) 公開 2023年3月29日 - マップ公開 2023年3月29日 - 更新 2023年4月12日 - 現状 2023年4月12日 処理サイト : PDBe / 状態 : 公開
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