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データを開く
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基本情報
登録情報 | ![]() |
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![]() | GON7, the fifth subunit of human KEOPS, bound to the EKC/KEOPS complex subunit, LAGE3
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機能・相同性 | ![]() tRNA threonylcarbamoyladenosine metabolic process / EKC/KEOPS complex / tRNA threonylcarbamoyladenosine modification / tRNA modification in the nucleus and cytosol / tRNA processing / nuclear body / nucleolus / nucleoplasm / nucleus / cytoplasm / cytosol 類似検索 - 分子機能 |
生物種 | ![]() |
![]() | ![]() タイトル: Defects in t6A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome 著者: Arrondel C / Missoury S / Snoek R / Patat J / Menara G / Collinet B / Liger D / Durand D / Gribouval O / Boyer O / Buscara L / Martin G / Machuca E / Nevo F / Lescop E / Braun D / Boschat A / ...著者: Arrondel C / Missoury S / Snoek R / Patat J / Menara G / Collinet B / Liger D / Durand D / Gribouval O / Boyer O / Buscara L / Martin G / Machuca E / Nevo F / Lescop E / Braun D / Boschat A / Sanquer S / Guerrera I / Revy P / Parisot M / Masson C / Boddaert N / Charbit M / Decramer S / Novo R / Macher M / Ranchin B / Bacchetta J / Laurent A / Collardeau-Frachon S / van Eerde A / Hildebrandt F / Magen D / Antignac C / van Tilbeurgh H |
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構造の表示
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-モデル
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試料
![]() | 名称: GON7, the fifth subunit of human KEOPS, bound to the EKC/KEOPS complex subunit, LAGE3 試料濃度: 0.7 mg/ml / Entity id: 1764 / 1765 |
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バッファ | 名称: 20 mM MES, 200 mM NaCl, 5 mM β-mercaptoethanol / pH: 6.5 |
要素 #1764 | 名称: GON7 / タイプ: protein / 記述: EKC/KEOPS complex subunit GON7 / 分子量: 12.59 / 分子数: 2 / 由来: Homo sapiens / 参照: UniProt: Q9BXV9 配列: MGHHHHHHEN LYFQGELLGE YVGQEGKPQK LRVSCEAPGD GDPFQGLLSG VAQMKDMVTE LFDPLVQGEV QHRVAAAPDE DLDGDDEDDA EDENNIDNRT NFDGPSAKRP KTPS |
要素 #1765 | 名称: LAGE3 / タイプ: protein / 記述: EKC/KEOPS complex subunit LAGE3 / 分子量: 16.478 / 分子数: 2 / 由来: Homo sapiens / 参照: UniProt: Q14657 配列: MHHHHHHENL YFQGRDADAD AGGGADGGDG RGGHSCRGGV DTAAAPAGGA PPAHAPGPGR DAASAARGSR MRPHIFTLSV PFPTPLEAEI AHGSLAPDAE PHQRVVGKDL TVSGRILVVR WKAEDCRLLR ISVINFLDQL SLVVRTMQRF GPPVSR |
-実験情報
ビーム | 設備名称: SOLEIL SWING ![]() ![]() | |||||||||||||||||||||||||||||||||
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検出器 | 名称: AVIEX PCCD170170 / タイプ: CCD | |||||||||||||||||||||||||||||||||
スキャン | 測定日: 2017年3月19日 / セル温度: 15 °C / 照射時間: 1 sec. / フレーム数: 255 / 単位: 1/A /
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距離分布関数 P(R) |
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結果 | コメント: The scattered intensities were displayed on an absolute scale (cm-1) using the scattering of water. SAXS data were normalized to the intensity of the incident beam, averaged and ...コメント: The scattered intensities were displayed on an absolute scale (cm-1) using the scattering of water. SAXS data were normalized to the intensity of the incident beam, averaged and background subtracted using the program US-SOMO. Frames were examined individually and 36 frames were averaged and further processed. The corresponding SEC-elution concentration was approximately 0.7 mg/mL.
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