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Yorodumi- SASDFK8: GON7, the fifth subunit of human KEOPS (EKC/KEOPS complex subunit... -
+Open data
-Basic information
Entry | Database: SASBDB / ID: SASDFK8 |
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Sample | GON7, the fifth subunit of human KEOPS
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Function / homology | EKC/KEOPS complex subunit GON7, metazoa / Domain of unknown function (DUF4611) / EKC/KEOPS complex / tRNA threonylcarbamoyladenosine modification / nucleolus / nucleoplasm / nucleus / cytosol / EKC/KEOPS complex subunit GON7 Function and homology information |
Biological species | Homo sapiens (human) |
Citation | Date: 2019 Dec Title: Defects in t6A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome Authors: Arrondel C / Missoury S / Snoek R / Patat J / Menara G / Collinet B / Liger D / Durand D / Gribouval O / Boyer O / Buscara L / Martin G / Machuca E / Nevo F / Lescop E / Braun D / Boschat A ...Authors: Arrondel C / Missoury S / Snoek R / Patat J / Menara G / Collinet B / Liger D / Durand D / Gribouval O / Boyer O / Buscara L / Martin G / Machuca E / Nevo F / Lescop E / Braun D / Boschat A / Sanquer S / Guerrera I / Revy P / Parisot M / Masson C / Boddaert N / Charbit M / Decramer S / Novo R / Macher M / Ranchin B / Bacchetta J / Laurent A / Collardeau-Frachon S / van Eerde A / Hildebrandt F / Magen D / Antignac C / van Tilbeurgh H |
Contact author |
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-Structure visualization
-Downloads & links
-Data source
SASBDB page | SASDFK8 |
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-Related structure data
Related structure data | C: citing same article (ref.) |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-Models
-Sample
Sample | Name: GON7, the fifth subunit of human KEOPS / Specimen concentration: 6.7 mg/ml |
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Buffer | Name: 20 mM MES, 200 mM NaCl, 5 mM β-mercaptoethanol / pH: 6.5 |
Entity #1756 | Name: GON7 / Type: protein / Description: EKC/KEOPS complex subunit GON7 / Formula weight: 12.59 / Num. of mol.: 1 / Source: Homo sapiens / References: UniProt: Q9BXV9 Sequence: MGHHHHHHEN LYFQGELLGE YVGQEGKPQK LRVSCEAPGD GDPFQGLLSG VAQMKDMVTE LFDPLVQGEV QHRVAAAPDE DLDGDDEDDA EDENNIDNRT NFDGPSAKRP KTPS |
-Experimental information
Beam | Instrument name: SOLEIL SWING / City: Saint-Aubin / 国: France / Type of source: X-ray synchrotronSynchrotron / Wavelength: 0.1 Å / Dist. spec. to detc.: 1.8 mm | |||||||||||||||||||||||||||||||||
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Detector | Name: AVIEX PCCD170170 / Type: CCD | |||||||||||||||||||||||||||||||||
Scan | Title: GON7, the fifth subunit of human KEOPS / Measurement date: Mar 26, 2017 / Cell temperature: 15 °C / Exposure time: 1 sec. / Number of frames: 255 / Unit: 1/A /
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Distance distribution function P(R) | Sofotware P(R): GNOM 5.0 / Number of points: 517 /
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Result | Type of curve: sec Comments: The scattered intensities were displayed on an absolute scale (cm-1) using the scattering of water. SAXS data were normalized to the intensity of the incident beam, averaged and background ...Comments: The scattered intensities were displayed on an absolute scale (cm-1) using the scattering of water. SAXS data were normalized to the intensity of the incident beam, averaged and background subtracted using the program US-SOMO. Frames were examined individually and 30 identical frames were averaged and further processed. The corresponding SEC-elution concentration was approximately 1.5 mg/mL.
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