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Yorodumi- SASDCS6: Rap guanine nucleotide exchange factor 3 (isoform3) bound to RAS ... -
+Open data
-Basic information
Entry | Database: SASBDB / ID: SASDCS6 |
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Sample | Rap guanine nucleotide exchange factor 3 (isoform3) bound to RAS related protein 1b - with cAMP
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Function / homology | Function and homology information cellular response to gonadotropin-releasing hormone / cellular response to xenobiotic stimulus => GO:0071466 / Rap protein signal transduction / regulation of cell junction assembly / positive regulation of integrin activation / response to carbohydrate / establishment of endothelial barrier / regulation of establishment of cell polarity / cellular response to cAMP / lipid droplet ...cellular response to gonadotropin-releasing hormone / cellular response to xenobiotic stimulus => GO:0071466 / Rap protein signal transduction / regulation of cell junction assembly / positive regulation of integrin activation / response to carbohydrate / establishment of endothelial barrier / regulation of establishment of cell polarity / cellular response to cAMP / lipid droplet / GDP binding / cell-cell junction / GTPase activity / protein-containing complex binding / GTP binding / membrane / cytosol Similarity search - Function |
Biological species | Homo sapiens (human) Mus musculus (house mouse) |
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Data source
SASBDB page | SASDCS6 |
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-Related structure data
Similar structure data |
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-External links
Related items in Molecule of the Month |
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-Models
Model #1144 | Type: atomic / Radius of dummy atoms: 1.90 A / Symmetry: P1 / Comment: Combined remodelled 3CF6 with 4F7Z and SwissModel / Chi-square value: 0.81 / P-value: 0.022800 Search similar-shape structures of this assembly by Omokage search (details) |
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Model #1145 | Type: dummy / Radius of dummy atoms: 3.75 A / Symmetry: P1 / Comment: SAXNS_DAMMIF / Chi-square value: 0.588289 / P-value: 0.008000 Search similar-shape structures of this assembly by Omokage search (details) |
-Sample
Sample | Name: Rap guanine nucleotide exchange factor 3 (isoform3) bound to RAS related protein 1b - with cAMP Specimen concentration: 1.00-4.00 / Entity id: 595 / 596 |
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Buffer | Name: 1mM EDTA, 10mM DTT, 500mM NaCl, 1mM cAMP, and 10mM Tris pH: 9 |
Entity #595 | Name: EPAC1B / Type: protein / Description: Rap guanine nucleotide exchange factor 3 / Formula weight: 100.001 / Num. of mol.: 1 / Source: Homo sapiens / References: UniProt: O95398-3 Sequence: GSPGIRVLVL RRMHRPRSCS YQLLLEHQRP SCIQGLRWTP LTNSEESLDF SESLEQASTE RVLRAGRQLH RHLLATCPNL IRDRKYHLRL YRQCCSGREL VDGILALGLG VHSRSQVVGI CQVLLDEGAL CHVKHDWAFQ DRDAQFYRFP GPEPEPVGTH EMEEELAEAV ...Sequence: GSPGIRVLVL RRMHRPRSCS YQLLLEHQRP SCIQGLRWTP LTNSEESLDF SESLEQASTE RVLRAGRQLH RHLLATCPNL IRDRKYHLRL YRQCCSGREL VDGILALGLG VHSRSQVVGI CQVLLDEGAL CHVKHDWAFQ DRDAQFYRFP GPEPEPVGTH EMEEELAEAV ALLSQRGPDA LLTVALRKPP GQRTDEELDL IFEELLHIKA VAHLSNSVKR ELAAVLLFEP HSKAGTVLFS QGDKGTSWYI IWKGSVNVVT HGKGLVTTLH EGDDFGQLAL VNDAPRAATI ILREDNCHFL RVDKQDFNRI IKDVEAKTMR LEEHGKVVLV LERASQGAGP SRPPTPGRNR YTVMSGTPEK ILELLLEAMG PDSSAHDPTE TFLSDFLLTH RVFMPSAQLC AALLHHFHVE PAGGSEQERS TYVCNKRQQI LRLVSQWVAL YGSMLHTDPV ATSFLQKLSD LVGRDTRLSN LLREQWPERR RCHRLENGCG NASPQMKARN LPVWLPNQDE PLPGSSCAIQ VGDKVPYDIC RPDHSVLTLQ LPVTASVREV MAALAQEDGW TKGQVLVKVN SAGDAIGLQP DARGVATSLG LNERLFVVNP QEVHELIPHP DQLGPTVGSA EGLDLVSAKD LAGQLTDHDW SLFNSIHQVE LIHYVLGPQH LRDVTTANLE RFMRRFNELQ YWVATELCLC PVPGPRAQLL RKFIKLAAHL KEQKNLNSFF AVMFGLSNSA ISRLAHTWER LPHKVRKLYS ALERLLDPSW NHRVYRLALA KLSPPVIPFM PLLLKDMTFI HEGNHTLVEN LINFEKMRMM ARAARMLHHC RSHNPVPLSP LRSRVSHLHE DSQVARISTC SEQSLSTRSP ASTWAYVQQL KVIDNQRELS RLSRELEP |
Entity #596 | Name: Rap1b / Type: protein / Description: RAS related protein 1b / Formula weight: 18 / Num. of mol.: 1 / Source: Mus musculus / References: UniProt: q52l50 Sequence: MREYKLVVLG SGGVGKSALT VQFVQGIFVE KYDPTIEDSY RKQVEVDAQQ CMLEILDTAG TEQFTAMRDL YMKNGQGFAL VYSITAQSTF NDLQDLREQI LRVKDTDDVP MILVGNKCDL EDERVVGKEQ GQNLARQWNN CAFLESSAKS KINVNEIFYD LVRQINR |
-Experimental information
Beam | Instrument name: Sealy Center For Structural Biology, UTMB-G Rigaku BioSAXS-1000 City: Galveston, TX / 国: USA / Type of source: X-ray in house / Wavelength: 0.15418 Å / Dist. spec. to detc.: 0.489 mm | |||||||||||||||||||||||||||||||||
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Detector | Name: Rigaku BioSAXS-1000 / Type: Kratky-2D / Pixsize x: 0.001 mm | |||||||||||||||||||||||||||||||||
Scan | Title: Rap guanine nucleotide exchange factor 3 (isoform3) bound to RAS related protein 1b - with cAMP Measurement date: Apr 1, 2013 / Storage temperature: 10 °C / Cell temperature: 10 °C / Exposure time: 1800 sec. / Number of frames: 5 / Unit: 1/A /
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Distance distribution function P(R) | Sofotware P(R): GNOM 4.5a / Number of points: 129 /
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Result | Type of curve: single_conc /
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