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Yorodumi- SASDC77: Deoxyuridine 5'-triphosphate nucleotidohydrolase complex with SaP... -
+Open data
-Basic information
Entry | Database: SASBDB / ID: SASDC77 |
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Sample | Deoxyuridine 5'-triphosphate nucleotidohydrolase complex with SaPIbov1 pathogenicity island repressor [3:3] (SEC-SAXS)
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Function / homology | Function and homology information dUTP catabolic process / dUMP biosynthetic process / dUTP diphosphatase / dUTP diphosphatase activity / Interconversion of nucleotide di- and triphosphates / nucleobase-containing compound metabolic process / dTMP biosynthetic process / DNA replication / magnesium ion binding / mitochondrion ...dUTP catabolic process / dUMP biosynthetic process / dUTP diphosphatase / dUTP diphosphatase activity / Interconversion of nucleotide di- and triphosphates / nucleobase-containing compound metabolic process / dTMP biosynthetic process / DNA replication / magnesium ion binding / mitochondrion / DNA binding / RNA binding / extracellular exosome / nucleoplasm / nucleus Similarity search - Function |
Biological species | Homo sapiens (human) Staphylococcus aureus (bacteria) |
Citation | Date: 2018 Mar 12 Title: Structural model of human dUTPase in complex with a novel proteinaceous inhibitor Authors: Nyíri K / Mertens H / Tihanyi B / Nagy G / Kőhegyi B / Matejka J / Harris M / Szabó J / Papp-Kádár V / Németh-Pongrácz V / Ozohanics O / Vékey K / Svergun D / Borysik A |
Contact author |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Data source
SASBDB page | SASDC77 |
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-Related structure data
Related structure data | C: citing same article (ref.) |
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Similar structure data |
-External links
Related items in Molecule of the Month |
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-Models
Model #1491 | Type: dummy / Software: (2.9.0) / Radius of dummy atoms: 3.40 A / Symmetry: P3 / Chi-square value: 1.066 Search similar-shape structures of this assembly by Omokage search (details) |
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Model #1492 | Type: mix / Software: (2.9.0) / Radius of dummy atoms: 1.90 A / Symmetry: P3 / Chi-square value: 1.41 Search similar-shape structures of this assembly by Omokage search (details) |
-Sample
Sample | Name: Deoxyuridine 5'-triphosphate nucleotidohydrolase complex with SaPIbov1 pathogenicity island repressor [3:3] (SEC-SAXS) Dry vol: 188384 / Entity id: 775 / 776 |
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Buffer | Name: 50 mM HEPES 300 mM NaCl 5 mM MgCl2 / pH: 7.5 / Comment: Buffer B |
Entity #775 | Name: hDUT / Type: protein Description: Deoxyuridine 5'-triphosphate nucleotidohydrolase Formula weight: 18.029 / Num. of mol.: 3 / Source: Homo sapiens / References: UniProt: P33316 Sequence: GSHMPCSEET PAISPSKRAR PAEVGGMQLR FARLSEHATA PTRGSARAAG YDLYSAYDYT IPPMEKAVVK TDIQIALPSG CYGRVAPRSG LAAKHFIDVG AGVIDEDYRG NVGVVLFNFG KEKFEVKKGD RIAQLICERI FYPEIEEVQA LDDTERGSGG FGSTGKN |
Entity #776 | Name: Stl / Type: protein / Description: SaPIbov1 pathogenicity island repressor / Formula weight: 32.016 / Num. of mol.: 2 / Source: Staphylococcus aureus / References: UniProt: E2FZP6 Sequence: GSPEFSMEGA GQMAELPTHY GTIIKTLRKY MKLTQSKLSE RTGFSQNTIS NHENGNRNIG VNEIEIYGKG LGIPSYILHR ISDEFKEKGY SPTLNDFGKF DKMYSYVNKA YYNDGDIYYS SYDLYDETIK LLELLKESKI NVNDIDYDYV LKLYKQILST DTEKSIINYE ...Sequence: GSPEFSMEGA GQMAELPTHY GTIIKTLRKY MKLTQSKLSE RTGFSQNTIS NHENGNRNIG VNEIEIYGKG LGIPSYILHR ISDEFKEKGY SPTLNDFGKF DKMYSYVNKA YYNDGDIYYS SYDLYDETIK LLELLKESKI NVNDIDYDYV LKLYKQILST DTEKSIINYE TLANTRKSSD KKREVTIEEI GEFHEKYLKL LFTNLETHND RKKALAEIEK LKEESIYLGE KLRLVPNHHY DAIKGKPMYK LYLYEYPDRL EHQKKIILEK DTN |
-Experimental information
Beam | Instrument name: PETRA III EMBL P12 / City: Hamburg / 国: Germany / Type of source: X-ray synchrotron / Wavelength: 0.124 Å / Dist. spec. to detc.: 3.1 mm | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Detector | Name: Pilatus 2M | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Scan | Title: hDUTstl_SEC_1 / Measurement date: Jul 10, 2016 / Storage temperature: 10 °C / Cell temperature: 10 °C / Exposure time: 1 sec. / Number of frames: 3600 / Unit: 1/nm /
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Distance distribution function P(R) | Sofotware P(R): GNOM 5.0 / Number of points: 1200 /
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Result | Type of curve: single_conc / Standard: water
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