登録情報 データベース : PDB / ID : 7n9s 構造の表示 ダウンロードとリンクタイトル TcdB and frizzled-2 CRD complex 要素 詳細 キーワード SIGNALING PROTEIN/Hydrolase / TOXIN / SIGNALING PROTEIN-Hydrolase complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
muscular septum morphogenesis / planar cell polarity pathway involved in neural tube closure / cochlea morphogenesis / hard palate development / WNT5A-dependent internalization of FZD2, FZD5 and ROR2 / non-canonical Wnt signaling pathway / membranous septum morphogenesis / Wnt receptor activity / inner ear receptor cell development / glucosyltransferase activity ... muscular septum morphogenesis / planar cell polarity pathway involved in neural tube closure / cochlea morphogenesis / hard palate development / WNT5A-dependent internalization of FZD2, FZD5 and ROR2 / non-canonical Wnt signaling pathway / membranous septum morphogenesis / Wnt receptor activity / inner ear receptor cell development / glucosyltransferase activity / endothelial cell differentiation / Wnt-protein binding / Class B/2 (Secretin family receptors) / Disassembly of the destruction complex and recruitment of AXIN to the membrane / Wnt signaling pathway, planar cell polarity pathway / host cell cytosol / 転移酵素; グリコシル基を移すもの; 六炭糖残基を移すもの / outflow tract morphogenesis / canonical Wnt signaling pathway / cysteine-type peptidase activity / host cell endosome membrane / Asymmetric localization of PCP proteins / TCF dependent signaling in response to WNT / PDZ domain binding / G protein-coupled receptor activity / clathrin-coated endocytic vesicle membrane / neuron differentiation / Wnt signaling pathway / positive regulation of DNA-binding transcription factor activity / sensory perception of smell / Ca2+ pathway / toxin activity / 加水分解酵素; プロテアーゼ; ペプチド結合加水分解酵素; システインプロテアーゼ / focal adhesion / lipid binding / host cell plasma membrane / positive regulation of DNA-templated transcription / proteolysis / extracellular region / membrane / metal ion binding / plasma membrane / cytoplasm 類似検索 - 分子機能 Frizzled 2, cysteine-rich domain / TcdA/TcdB toxin, N-terminal helical domain / TcdB toxin N-terminal helical domain / TcdA/TcdB toxin, catalytic glycosyltransferase domain / TcdA/TcdB catalytic glycosyltransferase domain / Dermonecrotic/RTX toxin, membrane localization domain / Membrane Localization Domain / Frizzled/Smoothened, transmembrane domain / Frizzled/Smoothened family membrane region / Frizzled/Smoothened family membrane region ... Frizzled 2, cysteine-rich domain / TcdA/TcdB toxin, N-terminal helical domain / TcdB toxin N-terminal helical domain / TcdA/TcdB toxin, catalytic glycosyltransferase domain / TcdA/TcdB catalytic glycosyltransferase domain / Dermonecrotic/RTX toxin, membrane localization domain / Membrane Localization Domain / Frizzled/Smoothened, transmembrane domain / Frizzled/Smoothened family membrane region / Frizzled/Smoothened family membrane region / TcdA/TcdB toxin, pore forming domain / TcdA/TcdB pore forming domain / Frizzled/secreted frizzled-related protein / Frizzled / CGT/MARTX, cysteine protease (CPD) domain / CGT/MARTX, cysteine protease (CPD) domain superfamily / Peptidase C80 family / CGT/MARTX cysteine protease (CPD) domain profile. / Frizzled domain / Frizzled cysteine-rich domain superfamily / Fz domain / Frizzled (fz) domain profile. / Choline-binding repeat / Putative cell wall binding repeat / Cell wall/choline-binding repeat / Cell wall-binding repeat profile. / GPCR, family 2-like / G-protein coupled receptors family 2 profile 2. / Nucleotide-diphospho-sugar transferases 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)Clostridioides difficile (バクテリア)手法 電子顕微鏡法 / 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度 : 5.1 Å 詳細データ登録者 Jiang, M. / Zhang, J. 資金援助 米国, 1件 詳細 詳細を隠す組織 認可番号 国 Welch Foundation 米国
引用ジャーナル : To Be Published タイトル : Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification著者 : Jiang, M. / Zhang, J. 履歴 登録 2021年6月18日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2022年3月2日 Provider : repository / タイプ : Initial release改定 1.1 2024年6月5日 Group : Data collection / カテゴリ : chem_comp_atom / chem_comp_bond
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