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Yorodumi- ChemComp-LBM: 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-... -
+Open data
-Basic information
Entry | Database: PDB chemical components / ID: LBM | ||||
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Name | Name: Synonyms: Venetoclax, Wikipedia | Wikipedia - Venetoclax: |
Venetoclax, sold under the brand names Venclexta and Venclyxto, is a medication used to treat adults with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or acute myeloid leukemia (AML). The most common side effects are low levels of neutrophils (a type of white blood cell), diarrhea, nausea, anemia (low red blood cell counts), nose and throat infection and tiredness. Venetoclax attaches to a protein called Bcl-2. This protein is present in high amounts in CLL cancer cells, where it helps the cells survive for longer in the body and makes them resistant to cancer medicines... Comment | medication*YM | |
-Chemical information
Composition | Formula: C45H50ClN7O7S / Number of atoms: 111 / Formula weight: 868.439 / Formal charge: 0 | ||||||||||||
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Others | Type: non-polymer / PDB classification: HETAIN / Three letter code: LBM / Ideal coordinates details: Corina / Model coordinates PDB-ID: 6O0P | ||||||||||||
History |
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External links | BindingDB / UniChem / ChEBI / ChEMBL / ChemicalBook / CompTox / DailyMed / DrugBank / GtoPharmacology / HMDB / PubChem / PubChem_TPharma / SureChEMBL / ZINC / ChemSpider / Wikipedia search / Google search |
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Details
-SMILES
ACDLabs 12.01 | CACTVS 3.385 | OpenEye OEToolkits 2.0.7 | |
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-SMILES CANONICAL
CACTVS 3.385 | OpenEye OEToolkits 2.0.7 | |
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-InChI
InChI 1.03 |
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-InChIKey
InChI 1.03 |
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-SYSTEMATIC NAME
ACDLabs 12.01 | OpenEye OEToolkits 2.0.7 | |
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