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Open data
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Basic information
Entry | Database: PDB / ID: 7kb8 | ||||||
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Title | Co-crystal structure of alpha glucosidase with compound 8 | ||||||
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![]() | HYDROLASE / Alpha glucosidase II / Endoplasmic reticulum / Inhibitor complex | ||||||
Function / homology | ![]() mannosyl-oligosaccharide alpha-1,3-glucosidase / glucosidase II complex / Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) / Post-translational protein phosphorylation / N-glycan processing / liver development / negative regulation of neuron projection development / in utero embryonic development / intracellular membrane-bounded organelle / calcium ion binding ...mannosyl-oligosaccharide alpha-1,3-glucosidase / glucosidase II complex / Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) / Post-translational protein phosphorylation / N-glycan processing / liver development / negative regulation of neuron projection development / in utero embryonic development / intracellular membrane-bounded organelle / calcium ion binding / protein-containing complex binding / endoplasmic reticulum / RNA binding Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Karade, S.S. / Mariuzza, R.A. | ||||||
![]() | ![]() Title: N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum alpha-Glucosidases I and II with Antiviral Activity. Authors: Karade, S.S. / Hill, M.L. / Kiappes, J.L. / Manne, R. / Aakula, B. / Zitzmann, N. / Warfield, K.L. / Treston, A.M. / Mariuzza, R.A. | ||||||
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 434.1 KB | Display | ![]() |
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PDB format | ![]() | 332.1 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Related structure data | ![]() 7jtyC ![]() 7k9nC ![]() 7k9oC ![]() 7k9qC ![]() 7k9tC ![]() 7kadC ![]() 7kb6C ![]() 7kbjC ![]() 7kbrC ![]() 7kryC ![]() 7l9eC ![]() 5f0eS S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Assembly
Deposited unit | ![]()
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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