+Open data
-Basic information
Entry | Database: PDB / ID: 6m5e | ||||||
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Title | Human serum albumin with cyclic peptide dalbavancin | ||||||
Components |
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Keywords | PEPTIDE BINDING PROTEIN / Transporter / Cyclic peptide | ||||||
Function / homology | Function and homology information cellular response to calcium ion starvation / exogenous protein binding / Ciprofloxacin ADME / enterobactin binding / Heme biosynthesis / HDL remodeling / negative regulation of mitochondrial depolarization / Prednisone ADME / Heme degradation / Aspirin ADME ...cellular response to calcium ion starvation / exogenous protein binding / Ciprofloxacin ADME / enterobactin binding / Heme biosynthesis / HDL remodeling / negative regulation of mitochondrial depolarization / Prednisone ADME / Heme degradation / Aspirin ADME / antioxidant activity / toxic substance binding / small molecule binding / Scavenging of heme from plasma / Recycling of bile acids and salts / cellular response to starvation / platelet alpha granule lumen / fatty acid binding / Post-translational protein phosphorylation / Cytoprotection by HMOX1 / Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) / pyridoxal phosphate binding / Platelet degranulation / protein-folding chaperone binding / blood microparticle / copper ion binding / endoplasmic reticulum lumen / Golgi apparatus / endoplasmic reticulum / protein-containing complex / DNA binding / extracellular space / extracellular exosome / extracellular region / identical protein binding / nucleus / cytoplasm Similarity search - Function | ||||||
Biological species | Homo sapiens (human) synthetic construct (others) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 2.8 Å | ||||||
Authors | Ito, S. / Senoo, A. / Nagatoishi, S. / Ohue, M. / Yamamoto, M. / Tsumoto, K. / Wakui, N. | ||||||
Funding support | Japan, 1items
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Citation | Journal: J.Med.Chem. / Year: 2020 Title: Structural Basis for the Binding Mechanism of Human Serum Albumin Complexed with Cyclic Peptide Dalbavancin. Authors: Ito, S. / Senoo, A. / Nagatoishi, S. / Ohue, M. / Yamamoto, M. / Tsumoto, K. / Wakui, N. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 6m5e.cif.gz | 719.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb6m5e.ent.gz | 602.4 KB | Display | PDB format |
PDBx/mmJSON format | 6m5e.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 6m5e_validation.pdf.gz | 1.8 MB | Display | wwPDB validaton report |
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Full document | 6m5e_full_validation.pdf.gz | 1.9 MB | Display | |
Data in XML | 6m5e_validation.xml.gz | 67.6 KB | Display | |
Data in CIF | 6m5e_validation.cif.gz | 91.8 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/m5/6m5e ftp://data.pdbj.org/pub/pdb/validation_reports/m5/6m5e | HTTPS FTP |
-Related structure data
Related structure data | 6m5dC 1ao6S S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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