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Yorodumi- PDB-5try: Structure of Mycobacterium tuberculosis proteasome in complex wit... -
+Open data
-Basic information
Entry | Database: PDB / ID: 5try | ||||||
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Title | Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2206 | ||||||
Components |
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Keywords | HYDROLASE/HYDROLASE inhibitor / N / C-capped dipeptides / Mycobacterium tuberculosis / proteasome / inhibitors / HYDROLASE-HYDROLASE inhibitor complex | ||||||
Function / homology | Function and homology information symbiont-mediated perturbation of host defenses / zymogen binding / proteasome endopeptidase complex / proteasome core complex, beta-subunit complex / proteasomal protein catabolic process / proteasome core complex, alpha-subunit complex / threonine-type endopeptidase activity / peptidoglycan-based cell wall / proteolysis involved in protein catabolic process / modification-dependent protein catabolic process ...symbiont-mediated perturbation of host defenses / zymogen binding / proteasome endopeptidase complex / proteasome core complex, beta-subunit complex / proteasomal protein catabolic process / proteasome core complex, alpha-subunit complex / threonine-type endopeptidase activity / peptidoglycan-based cell wall / proteolysis involved in protein catabolic process / modification-dependent protein catabolic process / proteasome-mediated ubiquitin-dependent protein catabolic process / extracellular region / plasma membrane / cytoplasm / cytosol Similarity search - Function | ||||||
Biological species | Mycobacterium tuberculosis (bacteria) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.00000818194 Å | ||||||
Authors | Hsu, H.-C. / Fan, H. / Singh, P.K. / Wang, R. / Sukenick, G. / Nathan, C. / Lin, G. / Li, H. | ||||||
Funding support | United States, 1items
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Citation | Journal: Biochemistry / Year: 2017 Title: Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome. Authors: Hsu, H.C. / Singh, P.K. / Fan, H. / Wang, R. / Sukenick, G. / Nathan, C. / Lin, G. / Li, H. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 5try.cif.gz | 1.4 MB | Display | PDBx/mmCIF format |
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PDB format | pdb5try.ent.gz | 949.1 KB | Display | PDB format |
PDBx/mmJSON format | 5try.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 5try_validation.pdf.gz | 4 MB | Display | wwPDB validaton report |
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Full document | 5try_full_validation.pdf.gz | 4.1 MB | Display | |
Data in XML | 5try_validation.xml.gz | 204.4 KB | Display | |
Data in CIF | 5try_validation.cif.gz | 266.7 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/tr/5try ftp://data.pdbj.org/pub/pdb/validation_reports/tr/5try | HTTPS FTP |
-Related structure data
Related structure data | 5thoC 5trgC 5trrC 5trsC 5ts0C 3hfaS C: citing same article (ref.) S: Starting model for refinement |
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Similar structure data |
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-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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