Entry | Database: PDB / ID: 4ihf |
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Title | Chasing Acyl Carrier Protein Through a Catalytic Cycle of Lipid A Production |
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Components | - Acyl carrier protein
- UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase
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Keywords | TRANSFERASE/LIPID BINDING PROTEIN / Acyl Carrier Protein / Left Handed Beta Helix / LpxD / acyltransferase / Lipid A / Protein-Protein complex / ACP Recognition Domain / ACP mediated product release / TRANSFERASE-LIPID BINDING PROTEIN complex |
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Function / homology | Function and homology information
UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity / UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase / N-acyltransferase activity / lipid A biosynthetic process / response to antibiotic / identical protein binding / cytosol / cytoplasmSimilarity search - Function UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD / UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region / UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD / MurE/MurF, N-terminal domain / Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 / Hexapeptide transferase, conserved site / Hexapeptide-repeat containing-transferases signature. / Hexapeptide repeat proteins / UDP N-Acetylglucosamine Acyltransferase; domain 1 / Hexapeptide repeat ...UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD / UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region / UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD / MurE/MurF, N-terminal domain / Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 / Hexapeptide transferase, conserved site / Hexapeptide-repeat containing-transferases signature. / Hexapeptide repeat proteins / UDP N-Acetylglucosamine Acyltransferase; domain 1 / Hexapeptide repeat / Bacterial transferase hexapeptide (six repeats) / Trimeric LpxA-like superfamily / 3 Solenoid / 3-Layer(aba) Sandwich / Mainly Beta / Alpha BetaSimilarity search - Domain/homology |
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Biological species | Escherichia coli (E. coli) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 2.1 Å |
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Authors | Masoudi, A. / Raetz, C.R.H. / Pemble, C.W. |
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Citation | Journal: Nature / Year: 2014 Title: Chasing acyl carrier protein through a catalytic cycle of lipid A production. Authors: Masoudi, A. / Raetz, C.R. / Zhou, P. / Pemble, C.W. |
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History | Deposition | Dec 18, 2012 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Nov 13, 2013 | Provider: repository / Type: Initial release |
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Revision 1.1 | Nov 20, 2013 | Group: Database references |
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Revision 1.2 | Jan 22, 2014 | Group: Database references |
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Revision 1.3 | Jan 29, 2014 | Group: Database references |
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Revision 1.4 | Nov 15, 2017 | Group: Advisory / Refinement description / Category: pdbx_unobs_or_zero_occ_atoms / software Item: _software.classification / _software.contact_author ..._software.classification / _software.contact_author / _software.contact_author_email / _software.date / _software.language / _software.location / _software.name / _software.type / _software.version |
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Remark 650 | HELIX DETERMINATION METHOD: AUTHOR |
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Remark 700 | SHEET DETERMINATION METHOD: AUTHOR |
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