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- EMDB-41284: Combined linker domain of N-DRC and associated proteins Tetrahymena -

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基本情報

登録情報
データベース: EMDB / ID: EMD-41284
タイトルCombined linker domain of N-DRC and associated proteins Tetrahymena
マップデータMain map
試料
  • 細胞: Combined linker domain of N-DRC and associated proteins Tetrahymena
    • タンパク質・ペプチド: x 24種
キーワードnexin-dynein regulatory complex / cilia (繊毛) / axoneme / dynein (ダイニン) / STRUCTURAL PROTEIN (タンパク質)
機能・相同性
機能・相同性情報


axonemal dynein complex assembly / inner dynein arm assembly / cilium movement / axoneme assembly / axonemal dynein complex / 繊毛 / axoneme / cell projection / 運動性 / 繊毛 ...axonemal dynein complex assembly / inner dynein arm assembly / cilium movement / axoneme assembly / axonemal dynein complex / 繊毛 / axoneme / cell projection / 運動性 / 繊毛 / small GTPase binding / microtubule binding / 微小管 / 細胞骨格 / calcium ion binding / ATP hydrolysis activity / ATP binding / 細胞質
類似検索 - 分子機能
Coiled-coil domain-containing protein 153 / Dynein regulatory complex subunit 7 / Dynein regulatory complex protein 10 / Cilia- and flagella-associated protein 91 / CFAP91 domain / Coiled-coil domain-containing protein 39 / Coiled-coil domain-containing protein 40 / Dynein regulatory complex protein 9 / Cilia- and flagella-associated protein 91 / Growth arrest-specific protein 8 domain ...Coiled-coil domain-containing protein 153 / Dynein regulatory complex subunit 7 / Dynein regulatory complex protein 10 / Cilia- and flagella-associated protein 91 / CFAP91 domain / Coiled-coil domain-containing protein 39 / Coiled-coil domain-containing protein 40 / Dynein regulatory complex protein 9 / Cilia- and flagella-associated protein 91 / Growth arrest-specific protein 8 domain / Growth arrest-specific protein 8 / Dynein regulatory complex protein 1/2, N-terminal / Dynein regulatory complex protein / Growth-arrest specific micro-tubule binding / 精子 / BRE1 E3 ubiquitin ligase / CFA20 domain / Cilia- and flagella-associated protein 20/CFAP20DC / CFA20 domain / EF-hand domain / Leucine rich repeat 4 / Leucine rich repeat, ribonuclease inhibitor type / Leucine Rich repeats (2 copies) / ロイシンリッチリピート / Leucine-rich repeat, SDS22-like subfamily / IQ motif profile. / IQ motif, EF-hand binding site / Leucine-rich repeat profile. / ロイシンリッチリピート / Papain-like cysteine peptidase superfamily / ATPase family associated with various cellular activities (AAA) / Leucine-rich repeat domain superfamily / ATPase, AAA-type, core / EF-hand, calcium binding motif / EF-Hand 1, calcium-binding site / EF-hand calcium-binding domain. / EF-hand calcium-binding domain profile. / EF-hand domain / EF-hand domain pair / WD40 repeat, conserved site / Trp-Asp (WD) repeats signature. / Trp-Asp (WD) repeats profile. / Trp-Asp (WD) repeats circular profile. / WD domain, G-beta repeat / WD40リピート / WD40リピート / WD40-repeat-containing domain superfamily / WD40/YVTN repeat-like-containing domain superfamily / P-loop containing nucleoside triphosphate hydrolase
類似検索 - ドメイン・相同性
Dynein regulatory complex protein 10 / Growth-arrest-specific microtubule-binding protein / AAA family ATPase CDC48 subfamily protein / Cilia- and flagella-associated protein 91 / Cilia- and flagella-associated protein 184 / Calmodulin 7-2 / Dynein regulatory complex subunit 3 / Coiled-coil lobo-like protein, putative / EF hand protein / Dynein regulatory complex protein 1/2 N-terminal domain-containing protein ...Dynein regulatory complex protein 10 / Growth-arrest-specific microtubule-binding protein / AAA family ATPase CDC48 subfamily protein / Cilia- and flagella-associated protein 91 / Cilia- and flagella-associated protein 184 / Calmodulin 7-2 / Dynein regulatory complex subunit 3 / Coiled-coil lobo-like protein, putative / EF hand protein / Dynein regulatory complex protein 1/2 N-terminal domain-containing protein / Cilia- and flagella-associated protein 263 / Cilia- and flagella-associated protein 20 / Coiled-coil domain-containing protein 153 / Coiled-coil protein, putative / WD40 domain protein / Flagella associated protein / Dynein regulatory complex protein 9 / Growth-arrest-specific microtubule-binding protein / Flagellar associated protein / Kinase domain protein / Dynein regulatory complex subunit 2 / WD40 domain protein / EF-hand calcium-binding domain protein
類似検索 - 構成要素
生物種Tetrahymena thermophila (真核生物)
手法単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.6 Å
データ登録者Ghanaeian AG / Majhi SM / McCaffrey CM / Nami BN / Black CB / Yang SK / Legal TL / Papoulas OP / Janowska MJ / Valente-Paterno MV ...Ghanaeian AG / Majhi SM / McCaffrey CM / Nami BN / Black CB / Yang SK / Legal TL / Papoulas OP / Janowska MJ / Valente-Paterno MV / Marcotte EM / Wloga DW / Bui KH
資金援助 カナダ, 2件
OrganizationGrant number国
Canadian Institutes of Health Research (CIHR) カナダ
Natural Sciences and Engineering Research Council (NSERC, Canada) カナダ
引用ジャーナル: Nat Commun / 年: 2023
タイトル: Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
著者: Avrin Ghanaeian / Sumita Majhi / Caitlyn L McCafferty / Babak Nami / Corbin S Black / Shun Kai Yang / Thibault Legal / Ophelia Papoulas / Martyna Janowska / Melissa Valente-Paterno / Edward M ...著者: Avrin Ghanaeian / Sumita Majhi / Caitlyn L McCafferty / Babak Nami / Corbin S Black / Shun Kai Yang / Thibault Legal / Ophelia Papoulas / Martyna Janowska / Melissa Valente-Paterno / Edward M Marcotte / Dorota Wloga / Khanh Huy Bui /
要旨: Cilia are hairlike protrusions that project from the surface of eukaryotic cells and play key roles in cell signaling and motility. Ciliary motility is regulated by the conserved nexin-dynein ...Cilia are hairlike protrusions that project from the surface of eukaryotic cells and play key roles in cell signaling and motility. Ciliary motility is regulated by the conserved nexin-dynein regulatory complex (N-DRC), which links adjacent doublet microtubules and regulates and coordinates the activity of outer doublet complexes. Despite its critical role in cilia motility, the assembly and molecular basis of the regulatory mechanism are poorly understood. Here, using cryo-electron microscopy in conjunction with biochemical cross-linking and integrative modeling, we localize 12 DRC subunits in the N-DRC structure of Tetrahymena thermophila. We also find that the CCDC96/113 complex is in close contact with the DRC9/10 in the linker region. In addition, we reveal that the N-DRC is associated with a network of coiled-coil proteins that most likely mediates N-DRC regulatory activity.
履歴
登録2023年7月19日-
ヘッダ(付随情報) 公開2023年9月27日-
マップ公開2023年9月27日-
更新2024年4月3日-
現状2024年4月3日処理サイト: RCSB / 状態: 公開

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構造の表示

添付画像

emd_41284.png

ダウンロードとリンク

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マップ

ファイルダウンロード / ファイル: emd_41284.map.gz / 形式: CCP4 / 大きさ: 401.1 MB / タイプ: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
注釈Main map
ボクセルのサイズX=Y=Z: 2.74 Å
密度
表面レベル登録者による: 0.545
最小 - 最大-1.58187 - 3.4972267
平均 (標準偏差)0.0069336235 (±0.2399834)
対称性空間群: 1
詳細

EMDB XML:

マップ形状
Axis orderXYZ
Origin-1-1-1
サイズ472472472
Spacing472472472
セルA=B=C: 1293.28 Å
α=β=γ: 90.0 °

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添付データ

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マスク #1

ファイルemd_41284_msk_1.map
投影像・断面図
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密度ヒストグラム

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ハーフマップ: Half map

ファイルemd_41284_half_map_1.map
注釈Half map
投影像・断面図
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断面 (1/2)
密度ヒストグラム

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ハーフマップ: Half map

ファイルemd_41284_half_map_2.map
注釈Half map
投影像・断面図
軸ZYX

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断面 (1/2)
密度ヒストグラム

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試料の構成要素

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全体 : Combined linker domain of N-DRC and associated proteins Tetrahymena

全体名称: Combined linker domain of N-DRC and associated proteins Tetrahymena
要素
  • 細胞: Combined linker domain of N-DRC and associated proteins Tetrahymena
    • タンパク質・ペプチド: Dynein regulatory complex protein 1/2 N-terminal domain-containing protein
    • タンパク質・ペプチド: Coiled-coil protein, putativeコイルドコイル
    • タンパク質・ペプチド: LRRC48 protein
    • タンパク質・ペプチド: Growth-arrest-specific microtubule-binding protein
    • タンパク質・ペプチド: Growth-arrest-specific microtubule-binding protein
    • タンパク質・ペプチド: Flagellar associated protein
    • タンパク質・ペプチド: Kinase domain protein
    • タンパク質・ペプチド: Coiled-coil lobo-like protein, putative
    • タンパク質・ペプチド: EF-hand calcium-binding domain protein
    • タンパク質・ペプチド: Dynein regulatory complex protein 9
    • タンパク質・ペプチド: Dynein regulatory complex protein 10
    • タンパク質・ペプチド: AAA family ATPase CDC48 subfamily protein
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 91
    • タンパク質・ペプチド: Flagella associated protein
    • タンパク質・ペプチド: Coiled-coil protein, putativeコイルドコイル
    • タンパク質・ペプチド: DUF4201 domain-containing protein
    • タンパク質・ペプチド: Calmodulin 7-2
    • タンパク質・ペプチド: Coiled-coil domain-containing protein 153
    • タンパク質・ペプチド: Flagellar associated protein
    • タンパク質・ペプチド: L-shape (Unknown-protein)
    • タンパク質・ペプチド: WD40 domain protein
    • タンパク質・ペプチド: EF hand proteinEFハンド
    • タンパク質・ペプチド: CFAP20
    • タンパク質・ペプチド: WD40 domain protein

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超分子 #1: Combined linker domain of N-DRC and associated proteins Tetrahymena

超分子名称: Combined linker domain of N-DRC and associated proteins Tetrahymena
タイプ: cell / ID: 1 / 親要素: 0 / 含まれる分子: all
由来(天然)生物種: Tetrahymena thermophila (真核生物)

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分子 #1: Dynein regulatory complex protein 1/2 N-terminal domain-containin...

分子名称: Dynein regulatory complex protein 1/2 N-terminal domain-containing protein
タイプ: protein_or_peptide / ID: 1 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 98.840125 KDa
配列文字列: MNPSQTQKGK IQIQVSRGSI DLLVRTMYED INNIKLKNER FQKKKRAEDE RRRRERYAEI QQEAIASGKK NAALEMKWAE LKELDECEE LNREMQDQQQ TFQQIIEGKE NLRKEFEEEL KRKDDEYVKM LKEQSNDIKD MISKMRSQFY KIRDANMQEL E DIERHFEQ ...文字列:
MNPSQTQKGK IQIQVSRGSI DLLVRTMYED INNIKLKNER FQKKKRAEDE RRRRERYAEI QQEAIASGKK NAALEMKWAE LKELDECEE LNREMQDQQQ TFQQIIEGKE NLRKEFEEEL KRKDDEYVKM LKEQSNDIKD MISKMRSQFY KIRDANMQEL E DIERHFEQ ERSNLLNEFK AKIQATFKKH LDLEEQYVKE HAKTEEEQTK NIEDLRIKGA KHYAELKITM ETEIQDLEKC FE DMKALYQ LITEKLDYSL KVLQEKFHEN NSMCDELKRK ENNFKNRLKQ LTKDYKQYDK KFKLENKNLT QEYKRIIRQF KEL QKKFKH FEKADLDKYS EIQKMNEAEV KELKDKIIKC NITIHIQQLG MQWIPPQSEE EILAQQKLQL EQGGKAEEEE EREF EFCIS EIKIGEICNI ILEEADFLID DKLREELEGS AEPEQIFQRL DCIKKCLYID SEDEMNLFFR ELITKCRVKS AEEIE EEAR KQLLLLGLIK EAEENENPEG EEVQQQEGAQ QKKKEEGNKK DDPKGKEGAK DSKENANPQG QNKSNQDERK KKKDGQ DDH AGQGQGQYDS NQGGMGENQE EGENAEGQEN LEGEIEKEID LENTQINLNE VVKFLQNWQA NKDKRKEKLE KESSKKA VK QETEREKKER IAREGKKYWE KLTQVLPERT FRIWNVNFFK FSFEKQILLN QINKLRFWTD LCPNIMNFFW TDKNQSKK P VNCITKMKNQ RIFQINTYKL IMNLLSALQD SLIQIKDKDD FIQTKISTNL FTFHNFQILL QIFIVNQSFL FIRLCQSYS KKIILLIKNI NQKLFNLSNF KNQFSF

UniProtKB: Dynein regulatory complex protein 1/2 N-terminal domain-containing protein

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分子 #2: Coiled-coil protein, putative

分子名称: Coiled-coil protein, putative / タイプ: protein_or_peptide / ID: 2 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 60.596348 KDa
配列文字列: MALLGKTLKG RSTRPGGIPQ KRNIKWRQLA KNQEEFDQLK QLAKMKREGL KARIKDEQKV VTFNKKKLIT YWRKIMRIAK TEQLKNEID IYSQNNQREL DSKEAFIQML DKNLDEAEDQ FQIALRNHLI HIENLMQLQE ARMRGLAEEF NRDVNILETE F DLEREEMV ...文字列:
MALLGKTLKG RSTRPGGIPQ KRNIKWRQLA KNQEEFDQLK QLAKMKREGL KARIKDEQKV VTFNKKKLIT YWRKIMRIAK TEQLKNEID IYSQNNQREL DSKEAFIQML DKNLDEAEDQ FQIALRNHLI HIENLMQLQE ARMRGLAEEF NRDVNILETE F DLEREEMV KTHKTQLKEL EDMIETVKEE DKKKTEEAQN EFSQFKEETK NKNLEETNVM KIILETKQTK YYTELEQMNS KF QSDTSNK VKDHQFYHAH NKNRKQEIDR YLRTISSKKA KIDLMKLKIL QHCKEFNARN SALKKEKENI SRNYHELKLK MQK FREEES RRLKELSNNS RNAVLKLREY CALGEKILKT AELCRRLETE KEKVLPFYES SVDEDQIPEQ LKNEFEHLKK EDAE EYAYL NNFYKRYNKV LLDKLAIEKQ KENLQRDNQL LKSLLKQYLD GISLNDDVLK NENNPLLVVN HKFNLGKMPV EKIEN KTVI EGVFEVRNTS HQLQGQRAPP FQ

UniProtKB: Dynein regulatory complex subunit 2

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分子 #3: LRRC48 protein

分子名称: LRRC48 protein / タイプ: protein_or_peptide / ID: 3 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 68.009617 KDa
配列文字列: MSNYISNYVQ STIVTKTVQN KDKKTGKNSV DPRVINEQLI LDAVKQFNQE NNKITTENII LQQLRQLQLS FKNILKIQHL QGLERLEKL QLDNNIIEKI ENIDHLVNLK WLDLSFNCIK KIEGLDKLKE LTDLSLFNNY IEKIEGLHNN TKLNVFSIGN N RLKSYEEI ...文字列:
MSNYISNYVQ STIVTKTVQN KDKKTGKNSV DPRVINEQLI LDAVKQFNQE NNKITTENII LQQLRQLQLS FKNILKIQHL QGLERLEKL QLDNNIIEKI ENIDHLVNLK WLDLSFNCIK KIEGLDKLKE LTDLSLFNNY IEKIEGLHNN TKLNVFSIGN N RLKSYEEI TLYFGYKPRG EEGTNDRPEF KRLQVLNVSG NPFTKDKENE YKNHIICAIP NLKYLDYVFI DEGDRQLIRQ DE QISNSYN FTTTDYYQQM QAQEQKEEMD RQTLKKKKDA RMDILDNLKD EYLKIEDLQR VKIIKPNQIN EEIEKYCGKI NDH VVEMQA AVIQKHQLIL QEMSKTEVSY KEQEALHEKE TLQILKEFEH EKKVEFRNWE KEAANGDAKK EESRLKTLLQ KTTS LKNKL MDIEIQLVEE LEAIFTDYDT KKKETAWKDI EEIIVLGQKK IEEENVKFYS NLNVIKNKEE ANYNSTQQQQ LEEEN NEED DEKASLLENK EQLAQMIGNI KETLIDSHTK IILSAQMELQ KDLAEYAKQQ KNKMYERNRK NISQIIAQID AYQTEI NEK LKQGDDESDH EN

UniProtKB: Dynein regulatory complex subunit 3

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分子 #4: Growth-arrest-specific microtubule-binding protein

分子名称: Growth-arrest-specific microtubule-binding protein / タイプ: protein_or_peptide / ID: 4 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 56.190844 KDa
配列文字列: MSKAAKAKKN VPVVSKLEAD ARKAAEGVND NESEEFKKAM RKEARALVEQ FNEEKKLLAF YQQERQKINY NWIIAKKELE DKKSELINK EREIQDLQEN HFMTLNVYKQ KIKHLLFQNQ DQQSELKKDV EVTLKQLEDQ HRIKSRELKT DVRSLKVTKK E QEISQQDY ...文字列:
MSKAAKAKKN VPVVSKLEAD ARKAAEGVND NESEEFKKAM RKEARALVEQ FNEEKKLLAF YQQERQKINY NWIIAKKELE DKKSELINK EREIQDLQEN HFMTLNVYKQ KIKHLLFQNQ DQQSELKKDV EVTLKQLEDQ HRIKSRELKT DVRSLKVTKK E QEISQQDY LFALKSEHDK QMTLMRQDYE RQVNDIKRKY DLKMQNLTKE MEEARAAMIK QLEDNKNQKI AEIIKEHTQK YN DIKNYYS EITATNLDYR KTLKNEIKEL QTKDEEYKKT LQQTEKGYKE LNEPLQALGI EIIQLKKQDE EQEAIIKEKE ELK QKIDNQ ERLFRKLEYE YEVKLQQFQY LERERNALYA KFNQTVFEIH QKSGLENLIL EKKVTNLRED LEIKDLQIHQ VLTA ANIDP NSVGSINKSL EEVESLKNEL ISELQAQLKQ IRKAHSHMVK AYEGKLSEFV IPVEELGFDP LVPTNTD

UniProtKB: Growth-arrest-specific microtubule-binding protein

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分子 #5: Growth-arrest-specific microtubule-binding protein

分子名称: Growth-arrest-specific microtubule-binding protein / タイプ: protein_or_peptide / ID: 5 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 55.393203 KDa
配列文字列: MPPKKAKGKK KKEEEPDDEY KSMTGADLTQ TLEKLKERVN EMRTNRNYIQ MDRDMVENFY HNTLKEISEV KTKISNKETE AEEKESKHR IDVKVFLQKV KHLEYEQEKS NLNIEDDGKK AKEKEDAYFE DITKNMKQLK TQLKSEYLEK EKANIQQVQE E KKDHQSLL ...文字列:
MPPKKAKGKK KKEEEPDDEY KSMTGADLTQ TLEKLKERVN EMRTNRNYIQ MDRDMVENFY HNTLKEISEV KTKISNKETE AEEKESKHR IDVKVFLQKV KHLEYEQEKS NLNIEDDGKK AKEKEDAYFE DITKNMKQLK TQLKSEYLEK EKANIQQVQE E KKDHQSLL KIQQKKFDEL INNLIIKYEE RLAKLKEDLE LKLKVEIHEL EERKNLHINE LMNNHEKAFA ELKKYYNDIT AE NLNLIKA HKEKIAQIYA NIQLNTKNVA DNQAKNEQLK EPLAKHREIR NKLKEDLKQF AKHKMSLQNL KSKAITLKDK ITK LERDGK DLDEKYEKVV REKQELEKKF EDITQEVKKN ADLNNNVLSN RLQILLKEYN NKEEELRTII DNAGLDHNLH EQLK QRVQQ SIEAKNTLIK NLKYSIHHAT KAYNDAIRVY EAKLVEFGIP IEELGFQPLE TITSSMPAGL VSS

UniProtKB: Growth-arrest-specific microtubule-binding protein

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分子 #6: Flagellar associated protein

分子名称: Flagellar associated protein / タイプ: protein_or_peptide / ID: 6 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 52.938457 KDa
配列文字列: MLAKKLALAR SQGKPDPFKK DEFPLLQHIA VEVVSQNYIL YPDLKGVPEN VRDTIISKIT TDLDILTMAP NIDQESFWQR ACKNRWEKS QKSINIEEHG RSWKVAYLER YMEEFLTNIQ NADDPNKKQI LQAELKAAAS WIHTLNLQNI NQNIDIDFIC K YLPLLTSL ...文字列:
MLAKKLALAR SQGKPDPFKK DEFPLLQHIA VEVVSQNYIL YPDLKGVPEN VRDTIISKIT TDLDILTMAP NIDQESFWQR ACKNRWEKS QKSINIEEHG RSWKVAYLER YMEEFLTNIQ NADDPNKKQI LQAELKAAAS WIHTLNLQNI NQNIDIDFIC K YLPLLTSL TLTYGTKYSG MDYNKQSVGM KLSEAANLGE AIKNCYSLLS LNISANMIDD DLLRFIMAGV NMNISLIELN LS HNKIEDQ GARRIAKFLM RNEILLYLNL GNNLIGYEGS RYLAQALKVN KNLQSLNLKL NNLGDKAGKK LFQDLMLNKT LLE LDVSGN QFEFETALKL SDYVADSMCG LKVLNIANND FNDSCYENLK TGFTKNYSLA KLDLRGNKFS KTQEEKEQEL KDPF RMFNL SQTEKELTQI IIRHDLTAQK IQFFSESDLD KIKQLKELQG AKQEPEKVIQ QDQNKE

UniProtKB: Flagellar associated protein

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分子 #7: Kinase domain protein

分子名称: Kinase domain protein / タイプ: protein_or_peptide / ID: 7 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 39.706977 KDa
配列文字列: MGDKKGKKKG GGEEDESTLQ LSRQYKKKCE LNGINPSKLF KEKLDFAVEE DENIEKIHLW EELGPVGVRS IMDSLTEIPY LHTKSIRLW KVKAQDEGTR TICNYMEKSK TIEYLDLMDN QVGSLGCEFL GRVLHPQIEI PLLKLKLDHN EFGTEGLMQL A AGLCMNSV ...文字列:
MGDKKGKKKG GGEEDESTLQ LSRQYKKKCE LNGINPSKLF KEKLDFAVEE DENIEKIHLW EELGPVGVRS IMDSLTEIPY LHTKSIRLW KVKAQDEGTR TICNYMEKSK TIEYLDLMDN QVGSLGCEFL GRVLHPQIEI PLLKLKLDHN EFGTEGLMQL A AGLCMNSV LEKLSLNYCA ITAEGSKYIQ QILSFVNTNL KKLKMKGNLL KNEGVHQLFR AFKVNKTLEK VDLSDNQFDT TL GDDQDPE ANPNFFETNK DAIEHNKQII ENICEVLKAA DTLLYYDFRF NNISKTDAKA IIDCLEANKN IYYMELSEHI PKD LIERKK GLMKKRKPKK KKKKKAKKK

UniProtKB: Kinase domain protein

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分子 #8: Coiled-coil lobo-like protein, putative

分子名称: Coiled-coil lobo-like protein, putative / タイプ: protein_or_peptide / ID: 8 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 101.225328 KDa
配列文字列: MDHNEGGYSH HQIEGQEGQQ QQAPVGGGGE DIFQVLENIT QVQNEKLKRC QEFKEQENIP RQYIENSPKE ELVLEHVIQF KRQFQYQLY YEDKRDLFLY PKNECDVYKF ICTTIRPTKL GFLELYDYQQ CSKYLSEFVQ YEELDPPNEF PLVIPSPTNV A VWQKGDCF ...文字列:
MDHNEGGYSH HQIEGQEGQQ QQAPVGGGGE DIFQVLENIT QVQNEKLKRC QEFKEQENIP RQYIENSPKE ELVLEHVIQF KRQFQYQLY YEDKRDLFLY PKNECDVYKF ICTTIRPTKL GFLELYDYQQ CSKYLSEFVQ YEELDPPNEF PLVIPSPTNV A VWQKGDCF DMSILLCSLL IGVGYDAYCV YGKAPREITT RNESLMECLF LEKGKYIEEN DKKPKQTLEQ NENALLKKPI AH SKWDQTQ ETKAREAEEE KRRIALTIND DEPDELLEDP YQGQRVHCWV LLRSGKRDVQ QNIFIEPSTG RMYSPSTCPY ECV DAVFNN LNFWINMKPE CEVKNLNFEE MDSSLNWEYV MLDTLLFNKG NGNDEEGNEN IDDPLNKQAQ RDPEQEQLQD IAQL LDMPP PWPPKIYIDK EKFLMGTPLG EGTVYYNKVK VDNYAPYSQP DGLVQKITIF QDYKRLKVKE YRYFYKHRSD KLSIR RRYP FEFKTIEEYE PQKYENKTIP QALQQWRQVI QIDRHLRIIK YYHNRNHDGL IERVEQIGEK TMMFYQNRDD RVIYRS IRF DNKRAPSSQN NDKVFQDNHV GDVQITKMTQ KFEKNPHYPA NEQIQKMVID LIKDKVIVYY HMNDGEITPI VKIYPRD SM HGFAKLNEPG GDNKIDDPLV QLENTKMVNL EKDCLNQLKQ QEKIARDDEK TIREGEIRLE KTLYDKARDR FKESSKKN D DDLAKDAAAS DYLYPYLEKR KLLGVSEINA QVAMEIKNEV MQKLKERLLS RAEIIQRRLE EQRQVLEQKE AQVAKRQEI DPKQEEEIRD INFKIDILEQ RALRFESMAL QKYEEMDNRL NKDARLAALH RK

UniProtKB: Coiled-coil lobo-like protein, putative

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分子 #9: EF-hand calcium-binding domain protein

分子名称: EF-hand calcium-binding domain protein / タイプ: protein_or_peptide / ID: 9 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 22.062066 KDa
配列文字列:
MYDPNTSQTE KQKQEEFLKL KIQEAFNLFV KDKKGIVDKR EIPYIMRYLG QFPSEAQVRD AILPEIEEDE PSEFIKYSKF EPYMLKVLK EREYEPDDPE ALLAAFKLLD QEGKGYIEID MMKTFLEKQG IEFREQETKS FIEFATNKDP NATVIYYEDY I SRLQAFTD KHIESVMKGY NNFQVKK

UniProtKB: EF-hand calcium-binding domain protein

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分子 #10: Dynein regulatory complex protein 9

分子名称: Dynein regulatory complex protein 9 / タイプ: protein_or_peptide / ID: 10 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 44.990227 KDa
配列文字列: MNQIDAHKLT IILRDATERL TFLDTINRQD DLSSELAGYE ISKLLKKQKN LENQYADLVQ LRTSLTGIQN KKNLIETQTK IVDVAQNLK ESTKKLCRLF KENPDLESDA LKVKKDRIQF MAVIEQLIQM VQNNSLTKFQ SMTTLELEDQ DRLRKLIFRE K ELYQEIKK ...文字列:
MNQIDAHKLT IILRDATERL TFLDTINRQD DLSSELAGYE ISKLLKKQKN LENQYADLVQ LRTSLTGIQN KKNLIETQTK IVDVAQNLK ESTKKLCRLF KENPDLESDA LKVKKDRIQF MAVIEQLIQM VQNNSLTKFQ SMTTLELEDQ DRLRKLIFRE K ELYQEIKK LQFDRNQENK EYDNEQKDTN LKIQNLKERL LYKKARAQLK NQYKEKEARA EEGTQQRMYE FEQKQLKEKI NN LKQKTDT ENMVHEQLRN FLIEKEDQIK QKSDEWAKKV ETCREQLQEE IDRLTVEKEK KQEELRELRE RDQKEQEEKD RRE RQELEE ADRKQQEELD QIRLDNAIKL IQIEYQEWKD AGGGKKKRKK GKKKKK

UniProtKB: Dynein regulatory complex protein 9

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分子 #11: Dynein regulatory complex protein 10

分子名称: Dynein regulatory complex protein 10 / タイプ: protein_or_peptide / ID: 11 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 51.315023 KDa
配列文字列: MQNLSKMQSR LHPRPEGEGG GGGGRTKEKG KSLQETHKEM LKNIESTNIG KPTIVEAQRI LKIIDNLSTN LTIFIYLDSE LISKFLDVA KHSKLSKDLV SKLSQRCLDL LKSQAEIEAK FKPYASLLDQ SNKEAEDVEE EKMIDAERLR MQLENNFKDL V RHLRNSPE ...文字列:
MQNLSKMQSR LHPRPEGEGG GGGGRTKEKG KSLQETHKEM LKNIESTNIG KPTIVEAQRI LKIIDNLSTN LTIFIYLDSE LISKFLDVA KHSKLSKDLV SKLSQRCLDL LKSQAEIEAK FKPYASLLDQ SNKEAEDVEE EKMIDAERLR MQLENNFKDL V RHLRNSPE DFEIIKSMKT NVNPDLNDLV HCIHCQKVIM LKKLSTASEE DENHKAQLRD LEEKIEELEK KKNKIQEDLT KL KEHRQKF SKEKKEELEK LKNEIAEVKA EKEKKASQLK NELDNRLKQL ERDHLAKKDK LDKELQKLED DFAKLKQDHA NDE TKLKTN KRQQQNSLAD NIESYDALMK DQHQKKQEIE EELAKIIEEV DTLKQLFKEI DEEKQREREL EEEFRLKKEQ WEIQ ERRKK EAARCILHFL MARKEKSKKK KKKKGKKKK

UniProtKB: Dynein regulatory complex protein 10

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分子 #12: AAA family ATPase CDC48 subfamily protein

分子名称: AAA family ATPase CDC48 subfamily protein / タイプ: protein_or_peptide / ID: 12 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 101.144125 KDa
配列文字列: MSNMMYNMKW QEAINDLMEQ VTLEYLPLEQ NEQQLGMKYK RDSSEWFHFW ATLYIKYIDI YKKLEDCYDQ LVHPQKRVLL KEMLENVIV RLCETKSQVV KYNTQYDATY KSDYPNLDEL VMDLKLTPDC LDIPIPRYFR EEDKKRLDER NQILDALLLE Y TDTKEPQE ...文字列:
MSNMMYNMKW QEAINDLMEQ VTLEYLPLEQ NEQQLGMKYK RDSSEWFHFW ATLYIKYIDI YKKLEDCYDQ LVHPQKRVLL KEMLENVIV RLCETKSQVV KYNTQYDATY KSDYPNLDEL VMDLKLTPDC LDIPIPRYFR EEDKKRLDER NQILDALLLE Y TDTKEPQE EQYEDQNTLQ ADMDTAIRII QRYERGRQGI ERANLAKILK KEEEKKLERQ KKLAEGTEIG EETEKDDAAL VI KKYWRGY KSRKLVQDIR EEELLFLGMK KVVEDPTLPE SQYKQAQNKR QKMKYIQEEH EQEFNDEIEN LKRLVKGNEG PDI LDKMRA ERREWIMREL EKNEFKEAPQ DPSEFYNQQV MDPEQQAAEA AKAAEEAKKK GAAKKDDKKK KGKPSELDEF LENN KPTGP SPIVLKLQEQ IEKHSGEWSK RDETNNFEQK HETELAKMLI KPVVEEQIKQ QVDEMIAEEL DIVRLRYDIK KKKQK KPPR PRNKGKNKKK FPGDSSNKGR DPKDILAGLV EKRVAKKLIP ASLMDLKGEQ NVLGKIQEIQ ADENLKKTEA LTDAKL KKA QLEEPSTKMP DPSIAQIRQI IAEYIAFPLG SKYAKEKLDK MNYFFFMGPR GSGKTLAVRA LAHECNAIVL DISPSNI DG QYTDKKQIDG MINSAFKVAK EFQPAIIYCE DFEYIFGQAK KKKSQVNPLF AKMKKPLMDF KKGKFFEPED RVVFIGST N RPWDCSQKEI KSFFDKKIYF PFPNYGTRML LFKTFLEQKK VPLPDNFPIN TIAHITEGWS AGSFKMAIDR VFTERRLQK INEEQIKLSE FIGPLSNVPF TSKEEFKEFK KFNQVVTGLQ ANYEAKKAPA DDQKGDKNKK KK

UniProtKB: AAA family ATPase CDC48 subfamily protein

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分子 #13: Cilia- and flagella-associated protein 91

分子名称: Cilia- and flagella-associated protein 91 / タイプ: protein_or_peptide / ID: 13 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 76.154328 KDa
配列文字列: MATTTNILHD VVRDQSMVNY VSNRDRPLYF KRPLVPQMTD IPLHISRPPV DQQVDYQTMQ MQQNATIVEA PTKDAFVQTD YRESETQTD PYTPKCFVRD GDHPEVMELK DYKYGKGLPA SIEELEQIEL NREKVWFENS LPPISDEASF NLRRKLMEEQ E LREWSKKE ...文字列:
MATTTNILHD VVRDQSMVNY VSNRDRPLYF KRPLVPQMTD IPLHISRPPV DQQVDYQTMQ MQQNATIVEA PTKDAFVQTD YRESETQTD PYTPKCFVRD GDHPEVMELK DYKYGKGLPA SIEELEQIEL NREKVWFENS LPPISDEASF NLRRKLMEEQ E LREWSKKE NEIKKFQNEK LYLLQQALIE REKEVEDKSQ ERIEEIRQQK TEHKNRQIAK IQRKKIKIDR KMTKSRKMQG KE TLKRDII EDYANFASRV YAGITHEGLS LDKIANKYEV QPLALGNYEM LQALHEGIRP REFETRVNLK KEIKEIEKNY TRL ENYHRG ELKKAQDEIN GVHEQSKAQQ KQEGNNFSYR NFENKIRPAT PTWKYDTDFN ISPSLITEIQ EYRGPNGVQL MQAA DKREE AVLLLQRLLR GRTTQNIMYE GKKKRTALIE ELLTVAQIEN LEEDKAEEVL MQQHEEKVKN AVLESIQGEV IAETM DELS KELLRIKQER KIQQMVEIAE KDRRIREIEE AGKRQAEEIL RDREDVLHNQ LIRVHQGTVD TYLDWLMSNA LEQSSA RQA TIMTNLRKAK FNLPLEDFER KYNNNQTLIK DLVHSFLIPN VQRSKLKKQI QLEEKRFSEA AKRSLQQTIT RASNKHA NV QN

UniProtKB: Cilia- and flagella-associated protein 91

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分子 #14: Flagella associated protein

分子名称: Flagella associated protein / タイプ: protein_or_peptide / ID: 14 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 114.163266 KDa
配列文字列: MDQGEFIQDD NDQDYDQQEG DDENNDYMED PQQDNNYNQN GDNLDDQGQD DDGGQNNLQQ PSVPPEDDED DDDDFPEYAN EQNKRLNEI IKKKRKLIKD ISAKIEEKSD RTKVLQEHLK NVEQELLHTQ ALIDAKNKEI ETEDHMKQIA ERQSGRIQSE L KILEKRSI ...文字列:
MDQGEFIQDD NDQDYDQQEG DDENNDYMED PQQDNNYNQN GDNLDDQGQD DDGGQNNLQQ PSVPPEDDED DDDDFPEYAN EQNKRLNEI IKKKRKLIKD ISAKIEEKSD RTKVLQEHLK NVEQELLHTQ ALIDAKNKEI ETEDHMKQIA ERQSGRIQSE L KILEKRSI EQQEKLNDVQ NQIFRGNEKM DQYKLEMNWN QEELEQWALA ARQKEEDNLT LEKYKRADEV KIKELNLAIE KL TAEVGRK QNELEKEITE TQAAQIELDK TAEEFKRQHE ERHKLFLQWQ EVTEIISKRD LAIREEGENF ARIKIEIKSN KDA LEERKR ILKEAKEENK RIQMANELME RQNIQQISDN KHIEEQLAEK KADVEILKNQ VSAFASDLSS KKNRIAILSQ ELLA KKQRL NAAQKKYQAH QVKLKNEEIM AKQYENDRSY AEEKYRKNEK EKKELEKEIR TQKENLFKHT QELFKHRERE ANLYG EIQG NMAACRNLQS HITKLNQEFQ RQQELLYNAE YQIQLMERRV ARAKGERTLE EKKDLENEIM NAERELGGVT GQNKEL IES LKNLDDEIRT VKKKLAYVEE ENTKYSSLIE ELILENDMTY QDLNKIIKQK EEVLVQHDTM KLEIKKINES LNGATEK VF NLENQIYQLE MSMQEREKEI EVHKDVLMTE HKAAEEERHK IAVELAERKN KVKNLKIKYE SLVQKNKASN GEVESVHE H SQAYYVIKAA QEREELQRKG DELNAKILKN EKELKALDNT LNHLKNRNSN YRDKFLNKGV TTQHREEAEG LEEQCRAAS QNLFKKRDEL QKLQKEQEED TRRYTEIKNK LERLYEQHQS LDQEISKYQK DIDQQGDKLQ RAQNSLQRNY QLAVNKNQNF INPKNPHMI QVKLDNQNNL YKTLLQGLYS LQQDIPELSS VVDEILKEQR IQNNKAPSSI DINSKRSSQS GRSQRSQRSN I SNQ

UniProtKB: Flagella associated protein

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分子 #15: Coiled-coil protein, putative

分子名称: Coiled-coil protein, putative / タイプ: protein_or_peptide / ID: 15 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 105.196055 KDa
配列文字列: MSNQQGPEDN NLEDDMAYLP ADHPLLAKLQ IDLTKQLTDE HERVDQKLIE IDANLKKLEK TKEDIGVRLY SVQQQLAENQ MNFEQAHEN YNWVQKLRIE AEQKLKTESE VYDAKKKELE ELRKKYLKAQ DELSKLTRTL YQINEFNQQM KGQIINTKTN T YRAEENVV ...文字列:
MSNQQGPEDN NLEDDMAYLP ADHPLLAKLQ IDLTKQLTDE HERVDQKLIE IDANLKKLEK TKEDIGVRLY SVQQQLAENQ MNFEQAHEN YNWVQKLRIE AEQKLKTESE VYDAKKKELE ELRKKYLKAQ DELSKLTRTL YQINEFNQQM KGQIINTKTN T YRAEENVV NLEAQKKKQD LLIDTMNEEI KRQTEQKTIL TAQLISQKEE TEQAKQILKE AHLEMQKIIA SKKNLLERWQ KS LMTMQRM DNALQAIKEA LKGQQELNLQ IGTELNGVNA EIRKETEIQE SLEGKNKKFD YEKDYLQKKY NELQEEKSKL EAQ INLLTQ SLRQTETEAG RAEIDKRNIE DQMNLIETNI MKLHTETKKL WEDLVHQKSE HTTIEKTATN LNKQANQISI EIED KSVEL ENLLNEIARV KIDQLNTLSQ IEVLENKRRE VIKEREEKEI TVATYEVQIR QGHDLNEKKQ HEVGRLNREH DKLSS VQSD MSRGPLEAKR NNLIRKTQEL GKENDLMQRE WIKKQTLLVT QNNRLNKIEE DVSQLKTKQT ILEQKKLRLN NNYRIY EKD IREIQNALKN LRNEMNKLND AIYRNKEKQQ KLDNENFNIK SEFVEKLKEL EKESVKLEVE IDRLKEEKAD LLAEIVE SE RQILLWERKI QLEKEMQDAL DPTVGQTEIQ ELKREIHRME LRLDDLRKKQ EAIIAEMERA VYKRETIQLK YMNKDKTF S NSNSMSQKSS SISAASDNSA QITKKIAQLK TTLNQTTRNA EQMEKAIKNK KIELDDLNAQ IEGNNDNLQK LESDCYNKN IELTKHKLER STNILSISCM QNKAKKLEDL VAGKARLSVP EATLMTKYEE LRDKNQEIKE ALQKLCDDAP QYVEVLNYLI DLNVGDDDE DQEQ

UniProtKB: Coiled-coil protein, putative

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分子 #16: DUF4201 domain-containing protein

分子名称: DUF4201 domain-containing protein / タイプ: protein_or_peptide / ID: 16 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 94.540883 KDa
配列文字列: MASEDGEMPS QFEGIDPEQL TESQMQQYMM EMQRQGLLDS NMEGGQYEEG YEEGQEGEGY GEEYGDQDYD GNQNEYDSQQ DSQQQGHDQ VNEMHQDRYD RRVNSEISGN YEADDETLRK IRRDLLDNIN LERRHRDLQP VYIDLTTNNI SQYYSEYLVN N EHNQDFYE ...文字列:
MASEDGEMPS QFEGIDPEQL TESQMQQYMM EMQRQGLLDS NMEGGQYEEG YEEGQEGEGY GEEYGDQDYD GNQNEYDSQQ DSQQQGHDQ VNEMHQDRYD RRVNSEISGN YEADDETLRK IRRDLLDNIN LERRHRDLQP VYIDLTTNNI SQYYSEYLVN N EHNQDFYE NAKVRYNNLG ECELCHITAK FEPDADITKE YIYDYFMEIG YLFLESEEEK RIILNPANNH IGIGVFFDEI QI VVVLILS EKVLCIQKIS QPEQNKIEIR GKMLDENFGI YAIRIMNVDD QKKDIKGVGP EFIEYTRSTQ EWMASFELEL YNQ DRMAIE YYTRVSPDSI PYKKKQSKNE KLTYKHLQLR LRTPFQIYPD PKYAAEDEKE RIRKEQEILA HEEQERKERE ENDA KRLKQ SRKDYGDGQY DDDEHGQDDF NSQSDISDKD KHHDSMHAEQ EQNQQAAQQQ QDTISNKEIR QELEMAITEA QRQHD EFML QNHKLQEEIK LLKNKNDGFV DRSNETAMNE HKYLNTLAHV HQIRLDLKQT QTRYNQMSQE LQKKLEQKQK KCNEIK YAF LELKREVAKK AANSRTDKPI PEQQINEWEK AELQKSKELQ ELRLQILRLR NAYVKNQKIL KKKEELAEGL HLIDFEQ LK IENQTLNEKI EERNEELHKL KKKNTTTIQI LTHTREKLGF VQGENGELNS QNVRKDQELD DMRKQLTQQK KTKDKLRS V NLTLKQQTGI VNSEELGQDY RDLRTRVSKL EEEKKRLEQK LRSMHEAIKT ANQISTQNMQ SQNNSLKKPY QPY

UniProtKB: Cilia- and flagella-associated protein 184

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分子 #17: Calmodulin 7-2

分子名称: Calmodulin 7-2 / タイプ: protein_or_peptide / ID: 17 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 23.862807 KDa
配列文字列: MDNTGKLEKQ LVTLNDGLPK KPAKEIIEEL KHHLYQDFQK FFSEEKKQQY QNNFALFDRD NDKYINLSEL KELLTSVNIT FPDDELEEL YNEFCLTSPE ADGINEDAVF IIVSKKIRDN DKDEQLTQAF KLVEKAVNDE LAKTPNETKE QEGYIRVEQF K ELLMTLGN ...文字列:
MDNTGKLEKQ LVTLNDGLPK KPAKEIIEEL KHHLYQDFQK FFSEEKKQQY QNNFALFDRD NDKYINLSEL KELLTSVNIT FPDDELEEL YNEFCLTSPE ADGINEDAVF IIVSKKIRDN DKDEQLTQAF KLVEKAVNDE LAKTPNETKE QEGYIRVEQF K ELLMTLGN RWSEEQANEF LKDINPKSDE RINYLDVVKK LMKR

UniProtKB: Calmodulin 7-2

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分子 #18: Coiled-coil domain-containing protein 153

分子名称: Coiled-coil domain-containing protein 153 / タイプ: protein_or_peptide / ID: 18 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 22.170178 KDa
配列文字列:
MSKKSGKGKG KNDGDELGAE KEQVLRTKVE SLIQRLGHEQ ERADRAKAAE NELRARLFDL DKDFKNEKDR LFSITSDMTR QYKQMQDEL LNQVNDLNKT VIEKDEEIKK KDQQIQDMTK DYEYKLKKKD DEIQDLKRKI EEMSAEFAKM LKDTLDKMQE R IEMVQWDS DTDPQMMKRL KDMTGLSNN

UniProtKB: Coiled-coil domain-containing protein 153

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分子 #19: Flagellar associated protein

分子名称: Flagellar associated protein / タイプ: protein_or_peptide / ID: 19 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 42.931082 KDa
配列文字列: MNQDKHPEIT DEEQELITVE ELSQKLELLY KDMEQIRREN LLFEAYLARN RKEIAKEDEV SEDKKGKGKK KDKNVDKKSL LLTNEEKFE IAQQEQDALK KQIDDGRIKS DQILETLRAI LEETDMAITE IRKDAFDFQR EILVGGENSR TGKIEAEKII K FFEEKERQ ...文字列:
MNQDKHPEIT DEEQELITVE ELSQKLELLY KDMEQIRREN LLFEAYLARN RKEIAKEDEV SEDKKGKGKK KDKNVDKKSL LLTNEEKFE IAQQEQDALK KQIDDGRIKS DQILETLRAI LEETDMAITE IRKDAFDFQR EILVGGENSR TGKIEAEKII K FFEEKERQ KDALIAKYSS KRTNLERQIL KTNNQIQKKE EMGDDLKFID FYQLQIENKK YVKEIDDKNK KLLALKISTN RI SQTLKDE KQNLKQELDK GKEYASQMSE RKKKISKIDA QIKSVKKVTS KLEKDRKIYD KQKEIFVQDN QDDVPQIMKY VQY KSKEQQ LLYAIQNLER KIEIAELAYK KANRILQSSQ QFQQK

UniProtKB: Cilia- and flagella-associated protein 263

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分子 #20: L-shape (Unknown-protein)

分子名称: L-shape (Unknown-protein) / タイプ: protein_or_peptide / ID: 20 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 50.825766 KDa
配列文字列: (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) ...文字列:
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)

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分子 #21: WD40 domain protein

分子名称: WD40 domain protein / タイプ: protein_or_peptide / ID: 21 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 151.719828 KDa
配列文字列: MAGLAQHIQL KYIFGMNNEI RNSLQFHDED RIIYPAGYNV VLHDLNDKSQ HYYQGTNEYR GISCLALSPL KRYLALGVKG QRDPAIIIF DTFTQKRRKN LGLNLGNLDR YNIKQWVSIA FPSQNQETKY IFSLSGAGGD VVLCWWWHEK GKCLGSIDLG A QNDIYEIS ...文字列:
MAGLAQHIQL KYIFGMNNEI RNSLQFHDED RIIYPAGYNV VLHDLNDKSQ HYYQGTNEYR GISCLALSPL KRYLALGVKG QRDPAIIIF DTFTQKRRKN LGLNLGNLDR YNIKQWVSIA FPSQNQETKY IFSLSGAGGD VVLCWWWHEK GKCLGSIDLG A QNDIYEIS FNHSDANSIC VTGNNFFGIY AKIEGTYVRE DNQQKQKPSV QNGENSSAAQ LPQPTLNIQV SAGNNNQNPQ PE IKLENGN LISNLPADIV EKNFVAHLWM QCESYLVVFV ESGEIILCDS RGNFLQIMEQ SPRYFIVSRS GMIKIVAAVA YSK GFYVAC SESIVLQYHY TQDNDKNPFT CVNQFKLKQF VELKEIEIKS ICMNKAEDKL LIGLDNNQIY EIKIKPYHPE TVNN DSSED REVTLINHLN HTGPINSMDI CKRKPIIATC STDKTIKIWD YEKKQIKISW AFNEEAFCLS LHPQGFCVAV GFLDK LRLM NLCIHNSQNT TKNKAYKEIS PFKGCKEIKF SNGGQYFAAV NSTSSNHVIQ VFKFFTGENP SQLVFKGHTG RVKCIA WSS DDSFLLSCGL DGMILAWKLD QDFQHQQTIV PRIVDIHNKG VNFSGLTLTV DNKTIVAVGN DRHIHQAVIN EQQPVDK TD KKLLDINLSC LAFPSSNKLL FAGIQDDARS SGAIRCFIYP LTHGKFTDYQ AHDERGVEKM KITNDDRYII TAGKDGCI M VFEIKDKDAR GMKLKDGYAK YSEEELITRS DLDDLKSTRD GLIVQINEFS NQNAMIGLNS RDDRIRQLET QIENNSQKR KQMFEQLLKS KTMEEQKLIQ EINEIKEQFE QEIQVMDTKY QKEVMSLVEE YENQKRLHEI ENNKNNKKKT KLLQEHSQKL QIIDDQYQK LLEEQITQKE RVEKQINHLQ KEQQEVLMQI SEEKETEIKN LNQKNSKDEQ AITDQGLKAK SDISITKKKI M QQQQEAQD LKEQKQEYER QKEKLKIQNQ ELRDKIDGQK KIILERDRTI GEKEKIIYNL KKKAQDLEKF KFVLDHKIKE LK RDIVPRE DEITKMKQET NNMDQYLKEL NAYNNYLGTV VDELYTTQET MKEDIKQQRQ QISVQQVKIS RFKDDVYSLA QHI LDYDKL VDETERLFMK HVNDKEVKRQ SVEGDIMMEY RSQKKNLEKL VNMFKKSLQK DNQIHKDDKI RIMKDNVDLI REIN TLRKS IKDITKGQQS NIPDQKGQTQ HMPLQTPQLS RKSISQPVLP PISKSAMFEG VTQQNEIQKS HTQINPELVE EKQKV LNSL QTDILELQKV YEALNYEKHN LTQA

UniProtKB: WD40 domain protein

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分子 #22: EF hand protein

分子名称: EF hand protein / タイプ: protein_or_peptide / ID: 22 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 124.971133 KDa
配列文字列: MSSDVKDSSH LEKQNSQEYS NSKQNGEIDI MEMLPQKKMY IIEKQFDQSG KGLKIDEFVR VMLTHLDFDK SDVQKEDQIT LALIDLFKE IDVNGDGTME WEEFSDHIIS LGLLRNDRSF KNVIKNYFPS EHIKDNQKHE TPIEKIVYFD KLKYLVVLEK D STRFKVYN ...文字列:
MSSDVKDSSH LEKQNSQEYS NSKQNGEIDI MEMLPQKKMY IIEKQFDQSG KGLKIDEFVR VMLTHLDFDK SDVQKEDQIT LALIDLFKE IDVNGDGTME WEEFSDHIIS LGLLRNDRSF KNVIKNYFPS EHIKDNQKHE TPIEKIVYFD KLKYLVVLEK D STRFKVYN ANTAELYYEV NAHKCAVLDA EYIPDQNLIA TSSNDLTINF WDSSFFIPKQ IVSVPEIQLC MRYAKWSTQS QP TYLYTGG SDSIIHIYDT KTLKEKGTIG GWNPFFKRDS QQYGHASPIG DILPINIQTT LVTAGLDANI CLWDAATHLP KKE LRGHEK GVYSLDWSDF SPMNQCLLSA GLDHEAFVWN TYVKEKIFLL RGHNHPLIGV KCLPGTPQVI TADINGMVKV WDVR NFLCM QTINVPTDEL NSFVVTSNQK KRIIFGARRL YYYEYDEPKD QMLTDEKMCL RVLYNSVLLC LITLHPDCIK VWDIR TGKL QSVYRELSTA ELTVCVLDTR KRKLFVGDAD GNIFTVNIKN GAKMKKFEKH NNRMITDLTH WTSKKPATIE IGGDDD DED GTGDSRRVVS CSREETVFIH DEDSSDPSRS CRYKMKQHKS SVNSLSLKQD SELFASASDD GNIVITNLNS YRQETLP ST QYPFEKKKVI FLDPYNALVT SDSEGYVHFY CVNNGKARTR YLLTKKYETT SVVNNKVDKF PVTHLAFNSD NNMLLLSD E LGNVTIWDLT IFLKKLDEIK DDNIQQQKTK QAQTPLKQTP NRASNGFFPT ELDELKQINE KQISLSQMDN LEKYFQDKD IAFVHQLKGA HNDGITWIEV LKEYNMFATS SFDCCCHLWS FNDYKKMGSL ILGHDIMNNN WQLRVDEEKR KVDAQYYMEK LKKKLNKDD QSDDEEKNSQ KQDESMMSDK NFDQKNQKKP KKTEKGEKGE KAPEKPLPEK KKVLTAQEKM EQNKKLKNEL K LEFDPALL NLNKNKKQVL SEKEQIEKAS ELLEKVKKFN DVIANKNKDR RNPLEIDYDD FLRAYQMDEQ VDIYLDQNEE EE EDNNILY DLDDPKNQSI PAGAYTSKGA FKSKNIGRKN KI

UniProtKB: EF hand protein

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分子 #23: CFAP20

分子名称: CFAP20 / タイプ: protein_or_peptide / ID: 23 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 22.976535 KDa
配列文字列: MFKNTFQSGF LSILYSIGSK PLQIWDKSIR NGHIKRITDQ DILSSVLEIM GTNVSTNYIT APADPKETLG IKLPFLVMII KNLKKYYTF EVQVLDDKNV RRRFRASNYQ STTRVKPFIC TMPMRLDEGW NQIQFNLSDF TRRAYATNYI ETLRVQIHAN C RIRRIYFS ...文字列:
MFKNTFQSGF LSILYSIGSK PLQIWDKSIR NGHIKRITDQ DILSSVLEIM GTNVSTNYIT APADPKETLG IKLPFLVMII KNLKKYYTF EVQVLDDKNV RRRFRASNYQ STTRVKPFIC TMPMRLDEGW NQIQFNLSDF TRRAYATNYI ETLRVQIHAN C RIRRIYFS DRLYSEEELP PEFKLFLPIQ GQNKTNV

UniProtKB: Cilia- and flagella-associated protein 20

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分子 #24: WD40 domain protein

分子名称: WD40 domain protein / タイプ: protein_or_peptide / ID: 24 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Tetrahymena thermophila (真核生物)
分子量理論値: 152.700203 KDa
配列文字列: MAQQIVQSLQ DEGTQSLKLD FSMKYVLGYR SDFKNNIFQY TMNDQNRIIY PAGNTIVISN NENKQQFINC IPGTKGITCM TLSPSKRLL AWSEDCDSGI IVVFDLIKLD KLEKAKNQNY QEPSDKDKLD KQAEKDRRDR FEKEKREKID KLQKEVKRII T TLDCKSRH ...文字列:
MAQQIVQSLQ DEGTQSLKLD FSMKYVLGYR SDFKNNIFQY TMNDQNRIIY PAGNTIVISN NENKQQFINC IPGTKGITCM TLSPSKRLL AWSEDCDSGI IVVFDLIKLD KLEKAKNQNY QEPSDKDKLD KQAEKDRRDR FEKEKREKID KLQKEVKRII T TLDCKSRH YVALDFNKIN EKRIVALSCA PDWQLIYFQL DKQKTVIINQ VPLKVGDNMR YTHCFFHPKE EDFIVAIGTG AI KPYKLGA DGQFKQKDPP FVKKESKDQA HSPNYLSYCI LQDGYMVIGT DMGEILLFQP SCEFKTILAS SPKNEQFAIQ CIQ PYSKGF LVGGKECTIL FYEKDVDLKN PYKLCSKKIQ FRDMKAMITS LLLTPNEEKL IVGVDSGQLL QVPFTSDSMQ LNEE NSKCE PLFMPFHSDK ITGLDVCIRK SLVATCSVDK TVRIWNYSDN QLENSKEFEE EAYAVAFHPS GFHIIVAFTE KIRLM NIFE NDLISFKELS VKNCREIQFS NGGHFFAITN VSMVQVFQFY TGENPSNLVF RGSGKVRTIF WEEDDQGFYT GSTDGL VIY WRVDDNGPQK TQIAQFNNLI ITSITGLYNP DTTTQGLERI LFVSGVSSSQ ENEGEKCVYK LVISCRQDKE GREITDN TL KKIYYVSQPE QKIFTGTNVS QIAISHSKKL FFFATEDRPG AIRITKYPFT NEIMEIQSHF GPITRMRISF KDNYIFTA G EDGALIIYEN KEKEYQVKIE NESVEAAAEE FLIPRDQYND QKREIEKLKR QLNEERMKQE QQIKEKMKDR DDKINQLEN QQKDSDNRDL NKYQLLEREK NEMIESYEEK KRMMKLQHEN NKRTIENEYK KKIALEMSRN EELAREKEKE EKRFQSEIQQ YQEEHLRQM EEKRRHYEEQ LAIEKQLYND LHLKREELAY KFDQKRNKLE MEAEELIDQL KEENESKMQV LFKNLEKAEI K KMDRRNDY DTEAQKLEEQ KSKLKGTMED ITSIQETNKM LQKEKESHAK EIDEREKTIR DKGRRIYELK KKTQELEKFK FV LDYKIKE LKRDIGPKEE EIAKMKEQIA NMNSEILHFK RTNANLKLIV TDLRLRQEGM KKEIEDQSKV IQQNNQYIKA FEQ DMSDCH QHIADYKKLK QKVLNLYNQY VQGDDSKKKR LENNDQQKEI MKERAHLETS VNNLKIKHDK NQSVHKSDTT IIMK HNTFL IFEINHLKRE KKKILEDKAK MLMQATQKKK QDGTSRVDID SLEKEIQKNE DEKRKLKEDI EKLRQYNDQI KNQLR QQIQ NQQDDDEDN

UniProtKB: WD40 domain protein

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実験情報

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構造解析

手法クライオ電子顕微鏡法
解析単粒子再構成法
試料の集合状態cell

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試料調製

緩衝液pH: 7.4
凍結凍結剤: ETHANE

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電子顕微鏡法

顕微鏡FEI TITAN KRIOS
電子線加速電圧: 300 kV / 電子線源: FIELD EMISSION GUN
電子光学系照射モード: FLOOD BEAM / 撮影モード: BRIGHT FIELDBright-field microscopy / 最大 デフォーカス（公称値）: 3.0 µm / 最小 デフォーカス（公称値）: 1.0 µm
撮影フィルム・検出器のモデル: GATAN K3 (6k x 4k) / 平均電子線量: 45.0 e/Å2
実験機器
モデル: Titan Krios / 画像提供: FEI Company

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画像解析

初期モデルモデルのタイプ: EMDB MAP
EMDB ID:

8537

初期 角度割当タイプ: NOT APPLICABLE
最終 角度割当タイプ: NOT APPLICABLE
最終 再構成解像度のタイプ: BY AUTHOR / 解像度: 3.6 Å / 解像度の算出法: OTHER / 使用した粒子像数: 211502
FSC曲線 (解像度の算出)

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

他の情報も見る