登録情報 データベース : PDB / ID : 3ewu 構造の表示 ダウンロードとリンクタイトル D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-acetyl-UMP, covalent adduct 要素Orotidine-5'-phosphate decarboxylase 詳細 キーワード LYASE / decarboxylation / unusual catalysis / tim barrel / Decarboxylase / Disease mutation / Glycosyltransferase / Multifunctional enzyme / Pyrimidine biosynthesis / Transferase機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
UMP biosynthetic process / orotate phosphoribosyltransferase / orotate phosphoribosyltransferase activity / pyrimidine nucleobase biosynthetic process / Pyrimidine biosynthesis / orotidine-5'-phosphate decarboxylase / orotidine-5'-phosphate decarboxylase activity / UDP biosynthetic process / 'de novo' UMP biosynthetic process / 'de novo' pyrimidine nucleobase biosynthetic process ... UMP biosynthetic process / orotate phosphoribosyltransferase / orotate phosphoribosyltransferase activity / pyrimidine nucleobase biosynthetic process / Pyrimidine biosynthesis / orotidine-5'-phosphate decarboxylase / orotidine-5'-phosphate decarboxylase activity / UDP biosynthetic process / 'de novo' UMP biosynthetic process / 'de novo' pyrimidine nucleobase biosynthetic process / lactation / female pregnancy / cellular response to xenobiotic stimulus / identical protein binding / nucleus / cytoplasm / cytosol 類似検索 - 分子機能 Orotate phosphoribosyl transferase domain / Orotate phosphoribosyltransferase / Purine/pyrimidine phosphoribosyl transferases signature. / Orotidine 5'-phosphate decarboxylase / Orotidine 5'-phosphate decarboxylase, active site / Orotidine 5'-phosphate decarboxylase active site. / Orotidine 5'-phosphate decarboxylase domain / Orotidine 5'-phosphate decarboxylase / HUMPS family / Orotidine 5'-phosphate decarboxylase / HUMPS family / Phosphoribosyl transferase domain ... Orotate phosphoribosyl transferase domain / Orotate phosphoribosyltransferase / Purine/pyrimidine phosphoribosyl transferases signature. / Orotidine 5'-phosphate decarboxylase / Orotidine 5'-phosphate decarboxylase, active site / Orotidine 5'-phosphate decarboxylase active site. / Orotidine 5'-phosphate decarboxylase domain / Orotidine 5'-phosphate decarboxylase / HUMPS family / Orotidine 5'-phosphate decarboxylase / HUMPS family / Phosphoribosyl transferase domain / Phosphoribosyltransferase-like / Phosphoribosyltransferase domain / Ribulose-phosphate binding barrel / Aldolase class I / Aldolase-type TIM barrel / TIM Barrel / Alpha-Beta Barrel / Alpha Beta 類似検索 - ドメイン・相同性 6-ethyluridine 5'-phosphate / Uridine 5'-monophosphate synthase 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.6 Å 詳細データ登録者 Heinrich, D. / Wittmann, J. / Diederichsen, U. / Rudolph, M. 引用ジャーナル : Chemistry / 年 : 2009タイトル : Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase著者 : Heinrich, D. / Diederichsen, U. / Rudolph, M.G. 履歴 登録 2008年10月16日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2009年4月7日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Non-polymer description / Version format compliance改定 1.2 2017年10月25日 Group : Refinement description / カテゴリ : software改定 1.3 2021年10月20日 Group : Database references / Derived calculationsカテゴリ : database_2 / struct_conn ... database_2 / struct_conn / struct_ref_seq_dif / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id 改定 1.4 2023年12月27日 Group : Data collection / カテゴリ : chem_comp_atom / chem_comp_bond
すべて表示 表示を減らす