Entry Database : PDB / ID : 2wei Structure visualization Downloads & linksTitle Crystal structure of the kinase domain of Cryptosporidium parvum calcium dependent protein kinase in complex with 3-MB-PP1 ComponentsCALMODULIN-DOMAIN PROTEIN KINASE 1, PUTATIVE Details Keywords TRANSFERASE / NUCLEOTIDE-BINDING / SERINE/THREONINE-PROTEIN KINASE / KINASE / ATP-BINDINGFunction / homology Function and homology informationFunction Domain/homology Component
calcium-dependent protein serine/threonine kinase activity / calcium/calmodulin-dependent protein kinase activity / calmodulin binding / intracellular signal transduction / phosphorylation / calcium ion binding / ATP binding / membrane / nucleus / cytoplasm Similarity search - Function EF-hand domain pair / EF-hand, calcium binding motif / EF-Hand 1, calcium-binding site / EF-hand calcium-binding domain. / EF-hand calcium-binding domain profile. / EF-hand domain / EF-hand domain pair / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 ... EF-hand domain pair / EF-hand, calcium binding motif / EF-Hand 1, calcium-binding site / EF-hand calcium-binding domain. / EF-hand calcium-binding domain profile. / EF-hand domain / EF-hand domain pair / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta Similarity search - Domain/homologyBiological species CRYPTOSPORIDIUM PARVUM IOWA II (eukaryote)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.65 Å DetailsAuthors Roos, A.K. / King, O. / Chaikuad, A. / Zhang, C. / Shokat, K.M. / Wernimont, A.K. / Artz, J.D. / Lin, L. / MacKenzie, F.I. / Finerty, P.J. ...Roos, A.K. / King, O. / Chaikuad, A. / Zhang, C. / Shokat, K.M. / Wernimont, A.K. / Artz, J.D. / Lin, L. / MacKenzie, F.I. / Finerty, P.J. / Vedadi, M. / Schapira, M. / Indarte, M. / Kozieradzki, I. / Pike, A.C.W. / Fedorov, O. / Doyle, D. / Muniz, J. / Arrowsmith, C.H. / Weigelt, J. / Edwards, A. / Bountra, C. / von Delft, F. / Heightman, T. / Hui, R. CitationJournal : Bmc Genomics / Year : 2011Title : The Cryptosporidium Parvum Kinome.Authors: Artz, J.D. / Wernimont, A.K. / Allali-Hassani, A. / Zhao, Y. / Amani, M. / Lin, Y.H. / Senisterra, G. / Wasney, G.A. / Fedorov, O. / King, O. / Roos, A.K. / Lunin, V.V. / Qiu, W. / Finerty, ... Authors : Artz, J.D. / Wernimont, A.K. / Allali-Hassani, A. / Zhao, Y. / Amani, M. / Lin, Y.H. / Senisterra, G. / Wasney, G.A. / Fedorov, O. / King, O. / Roos, A.K. / Lunin, V.V. / Qiu, W. / Finerty, P.J. / Hutchinson, A. / Chau, I. / von Delft, F. / MacKenzie, F.I. / Lew, J. / Kozieradzki, I. / Vedadi, M. / Schapira, M. / Zhang, C. / Shokat, K.M. / Heightman, T. / Hui, R. History Deposition Mar 31, 2009 Deposition site : PDBE / Processing site : PDBERevision 1.0 Apr 28, 2009 Provider : repository / Type : Initial releaseRevision 1.1 Jul 13, 2011 Group : Advisory / Version format complianceRevision 1.2 Oct 12, 2011 Group : Database references / Derived calculations / Refinement descriptionRevision 1.3 Dec 5, 2012 Group : Database references / Structure summaryRevision 1.4 Jan 24, 2018 Group : Database references / Structure summary / Category : audit_author / citation_author / Item : _audit_author.name / _citation_author.nameRevision 1.5 Dec 13, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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