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-Structure paper
| タイトル | A sensory system for mating in octopus. |
|---|---|
| ジャーナル・号・ページ | Science, Vol. 392, Issue 6793, Page 96-9101, Year 2026 |
| 掲載日 | 2026年4月2日 |
著者 | Pablo S Villar / Hao Jiang / Tatiana Shugaeva / Emma L Berdan / Arpita Kulkarni / Makoto Hiroi / Giovanni Masucci / Sam Reiter / Erik Lindahl / Rebecca J Howard / Ryan E Hibbs / Nicholas W Bellono / ![]() |
| PubMed 要旨 | Sensory systems for mate recognition maintain species boundaries and influence diversification. Thus, uncovering how molecules and receptors evolve to mediate this critical function is essential to ...Sensory systems for mate recognition maintain species boundaries and influence diversification. Thus, uncovering how molecules and receptors evolve to mediate this critical function is essential to understanding biodiversity. Male octopuses use a specialized arm called the hectocotylus to identify females and navigate their internal organs to reach the oviduct and deliver sperm. Here, we discovered that the hectocotylus is a dual sensory and mating organ that uses contact-dependent chemosensation of progesterone, a conserved ovarian hormone. We identified chemotactile receptors for progesterone and resolved the structural basis for their evolution from ancestral neurotransmitter receptors and subsequent expansion and tuning across cephalopods. These findings reveal principles by which sensory innovations shape reproductive behavior and suggest mechanisms for how sensory evolution contributes to the diversification of life. |
リンク | Science / PubMed:42012846 |
| 手法 | EM (単粒子) |
| 解像度 | 2.8 Å |
| 構造データ | EMDB-72977, PDB-9yi4: |
| 化合物 | ![]() ChemComp-NAG: ![]() ChemComp-STR: |
| 由来 |
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キーワード | MEMBRANE PROTEIN / complex |
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octopus bimaculoides (無脊椎動物)
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