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TitleStructure of the human signal peptidase complex with a signal peptide
Journal, issue, pagesNat Commun, Year 2026
Publish dateJun 12, 2025 (structure data deposition date)
AuthorsLiaci AM / Vismpas D / Kjolbye LR / Skalidis I / Periera GP / Koh AF / Grollers-Mulderij M / Kotecha A / Souza PCT / Forster FG
External linksNat Commun / Search PubMed
MethodsEM (single particle)
Resolution2.6 - 4.2 Å
Structure data

54010

9rjb

EMDB-54010, PDB-9rjb:
Human Signal Peptidase in complex with artificial Signal Peptide L11
Method: EM (single particle) / Resolution: 2.6 Å

54011

9rjc

EMDB-54011, PDB-9rjc:
Apo Structure of the Human Signal Peptidase
Method: EM (single particle) / Resolution: 4.2 Å

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / Signal Peptidase Complex / Signal Peptide / protein biogenesis / secretory pathway / membrane thinning

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