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Titlea5b3 GABAAR bound to Etomidate, GABA, and Mb25 in a desensitized state in saposin nanodiscs
Journal, issue, pagesTo Be Published
Publish dateDec 11, 2024 (structure data deposition date)
AuthorsCowgill J / Fan C / Howard RJ / Lindahl E
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.32 Å
Structure data

52315

9hnt

EMDB-52315, PDB-9hnt:
a5b3 GABAAR bound to Etomidate, GABA, and Mb25 in a desensitized state in saposin nanodiscs
Method: EM (single particle) / Resolution: 3.32 Å

Chemicals

ChemComp-V8D:
Etomidate

ChemComp-ABU:
GAMMA-AMINO-BUTANOIC ACID / neurotransmitter, inhibitor*YM

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • escherichia coli (E. coli)
  • aequorea victoria (jellyfish)
KeywordsMEMBRANE PROTEIN / GABA receptor / pentameric ligand gated ion channel / cys-loop receptor

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