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Structure paper

TitleMolecular features defining the efficiency of bioPROTACs.
Journal, issue, pagesCommun Biol, Vol. 8, Page 946-946, Year 2025
Publish dateApr 22, 2024 (structure data deposition date)
AuthorsWinkelvoss, D. / Vukovic, D. / Hanny, A.C. / Riermeier, L. / Udovcic, A. / Kolibius, J. / Honegger, A. / Mittl, P.R.E. / Michel, E. / Hansen, S. / Pluckthun, A.
External linksCommun Biol / PubMed:40542219
MethodsX-ray diffraction
Resolution1.59 - 2.2 Å
Structure data

PDB-9f22:
DARPin eGFP complex DP1 (3G190.24)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-9f23:
DARPin eGFP complex DP2 (2G156)
Method: X-RAY DIFFRACTION / Resolution: 1.59 Å

PDB-9f24:
DARPin eGFP complex DP4 (2G71)
Method: X-RAY DIFFRACTION / Resolution: 2.06 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-BR:
BROMIDE ION

ChemComp-HOH:
WATER

PDB-1h87:
Gadolinium derivative of tetragonal Hen Egg-White Lysozyme at 1.7 A resolution

ChemComp-NA:
Unknown entry

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-PXN:
(2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol

Source
  • aequorea victoria (jellyfish)
  • synthetic construct (others)
KeywordsPROTEIN BINDING / DARPin / GFP

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