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Structure paper

TitleStructure of the Outer Membrane Transporter FemA and Its Role in the Uptake of Ferric Dihydro-Aeruginoic Acid and Ferric Aeruginoic Acid in Pseudomonas aeruginosa .
Journal, issue, pagesAcs Chem. Biol., Vol. 20, Page 690-706, Year 2025
Publish dateFeb 19, 2024 (structure data deposition date)
AuthorsWill, V. / Moynie, L. / Si Ahmed Charrier, E. / Le Bas, A. / Kuhn, L. / Volck, F. / Chicher, J. / Aksoy, H. / Madec, M. / Antheaume, C. ...Will, V. / Moynie, L. / Si Ahmed Charrier, E. / Le Bas, A. / Kuhn, L. / Volck, F. / Chicher, J. / Aksoy, H. / Madec, M. / Antheaume, C. / Mislin, G.L.A. / Schalk, I.J.
External linksAcs Chem. Biol. / PubMed:40035455
MethodsX-ray diffraction
Resolution1.86 - 2.2 Å
Structure data

PDB-8s34:
Ferric-mycobactin receptor (FemA) in complex with aeruginic acid
Method: X-RAY DIFFRACTION / Resolution: 1.86 Å

PDB-9ex3:
Ferric-mycobactin receptor (FemA) in complex with dihydroaeruginoic acid
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-9f2t:
Ferric-mycobactin receptor (FemA)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-9fvq:
Ferric-mycobactin receptor (FemA) in complex with pyochelin
Method: X-RAY DIFFRACTION / Resolution: 2.031 Å

Chemicals

ChemComp-C8E:
(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE / C8E, detergent*YM

PDB-1h49:
CRYSTAL STRUCTURE OF THE INACTIVE DOUBLE MUTANT OF THE MAIZE BETA-GLUCOSIDASE ZMGLU1-E191D-F198V IN COMPLEX WITH DIMBOA-GLUCOSIDE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-P2D:
pentane-2,4-dione

ChemComp-FE:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-J9F:
(4S)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid

ChemComp-ACT:
ACETATE ION

ChemComp-188:
PYOCHELIN FE(III)

PDB-1ig8:
Crystal Structure of Yeast Hexokinase PII with the correct amino acid sequence

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsMEMBRANE PROTEIN / TonB-dependent transporter / Pyochelin / TonB dependent transporter

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