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Structure paper

TitleStructural insights into the catalytic mechanism of the AP endonuclease AtARP.
Journal, issue, pagesStructure, Vol. 32, Page 780-794.e5, Year 2024
Publish dateAug 2, 2023 (structure data deposition date)
AuthorsGuo, W. / Wu, W. / Wen, Y. / Gao, Y. / Zhuang, S. / Meng, C. / Chen, H. / Zhao, Z. / Hu, K. / Wu, B.
External linksStructure / PubMed:38503293
MethodsX-ray diffraction
Resolution2.3 - 3 Å
Structure data

PDB-8ka3:
Arabidopsis AP endonuclease ARP complex with 22bp THF-containing DNA
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-8ka4:
Arabidopsis AP endonuclease ARP complex with 21bp THF-containing DNA
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-8ka5:
Arabidopsis AP endonuclease ARP complex with 20bp THF-containing DNA
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-3DR:
1',2'-DIDEOXYRIBOFURANOSE-5'-PHOSPHATE

ChemComp-HOH:
WATER

ChemComp-DGP:
2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE

ChemComp-PO4:
PHOSPHATE ION

Source
  • arabidopsis thaliana (thale cress)
  • synthetic construct (others)
KeywordsHYDROLASE/DNA / AP / abasic site / endonuclease / Arabidopsis / HYDROLASE-DNA complex / HYDROLASE

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